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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.971585292489]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
CCC1
  • membrane fraction
  • fungal-type vacuole membrane
  • Golgi apparatus
    		•
  • cellular iron ion homeostasis
  • cellular manganese ion homeostasis
  • cellular calcium ion homeostasis
    		•
  • manganese ion transmembrane transporter activity
  • ferrous iron transmembrane transporter activity
    		•
    PMC1
  • fungal-type vacuole membrane
    		•
  • calcium ion transport
  • cellular calcium ion homeostasis
    		•
  • calcium-transporting ATPase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    fungal-type vacuole membrane 1.3647E-4 2 74 2 6292
    vacuolar membrane 3.1973E-4 2 113 2 6292
    vacuolar part 3.6682E-4 2 121 2 6292
    fungal-type vacuole 6.2668E-4 2 158 2 6292
    lytic vacuole 6.2668E-4 2 158 2 6292
    storage vacuole 6.2668E-4 2 158 2 6292
    vacuole 1.0983E-3 2 209 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    calcium ion homeostasis 1.819E-6 2 9 2 6292
    cellular calcium ion homeostasis 1.819E-6 2 9 2 6292
    metal ion homeostasis 9.6001E-6 2 20 2 6292
    cellular metal ion homeostasis 9.6001E-6 2 20 2 6292
    cellular di-, tri-valent inorganic cation homeostasis 1.0838E-4 2 66 2 6292
    di-, tri-valent inorganic cation homeostasis 1.0838E-4 2 66 2 6292
    cellular cation homeostasis 2.7588E-4 2 105 2 6292
    cation homeostasis 2.974E-4 2 109 2 6292
    cellular chemical homeostasis 3.5475E-4 2 119 2 6292
    cellular ion homeostasis 3.5475E-4 2 119 2 6292
    cellular homeostasis 3.6076E-4 2 120 2 6292
    chemical homeostasis 3.791E-4 2 123 2 6292
    ion homeostasis 3.791E-4 2 123 2 6292
    manganese ion homeostasis 1.5888E-3 2 5 1 6292
    calcium ion transport 1.5888E-3 2 5 1 6292
    cellular manganese ion homeostasis 1.5888E-3 2 5 1 6292
    divalent metal ion transport 3.1764E-3 2 10 1 6292
    homeostatic process 4.1951E-3 2 408 2 6292
    regulation of biological quality 7.6561E-3 2 551 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    di-, tri-valent inorganic cation transmembrane transporter activity 3.0063E-5 2 35 2 6292
    metal ion transmembrane transporter activity 5.2295E-5 2 46 2 6292
    inorganic cation transmembrane transporter activity 2.5516E-4 2 101 2 6292
    ferrous iron transmembrane transporter activity 3.1786E-4 2 1 1 6292
    cation transmembrane transporter activity 3.4879E-4 2 118 2 6292
    ion transmembrane transporter activity 5.3483E-4 2 146 2 6292
    calcium-transporting ATPase activity 6.3568E-4 2 2 1 6292
    calcium ion transmembrane transporter activity 9.5344E-4 2 3 1 6292
    substrate-specific transmembrane transporter activity 1.7943E-3 2 267 2 6292
    manganese ion transmembrane transporter activity 1.9064E-3 2 6 1 6292
    transmembrane transporter activity 2.3578E-3 2 306 2 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    iron ion transmembrane transporter activity 3.811E-3 2 12 1 6292
    transporter activity 4.1132E-3 2 404 2 6292
    ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 4.4455E-3 2 14 1 6292
    cation-transporting ATPase activity 5.0798E-3 2 16 1 6292
    transition metal ion transmembrane transporter activity 8.8811E-3 2 28 1 6292
    ATPase activity, coupled to transmembrane movement of ions 9.1975E-3 2 29 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle