| From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
| Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.974689580623] |
| Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| pre-replicative complex | 6.0632E-6 | 2 | 16 | 2 | 6292 |
| protein-DNA complex | 8.0641E-5 | 2 | 57 | 2 | 6292 |
| nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
| nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
| chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
| nucleoplasm part | 1.5102E-3 | 2 | 245 | 2 | 6292 |
| nucleoplasm | 1.7541E-3 | 2 | 264 | 2 | 6292 |
| chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
| origin recognition complex | 1.9064E-3 | 2 | 6 | 1 | 6292 |
| nuclear origin of replication recognition complex | 1.9064E-3 | 2 | 6 | 1 | 6292 |
| MCM complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
| nuclear lumen | 5.1728E-3 | 2 | 453 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| pre-replicative complex assembly | 3.9411E-6 | 2 | 13 | 2 | 6292 |
| DNA replication initiation | 2.6678E-5 | 2 | 33 | 2 | 6292 |
| protein-DNA complex assembly | 3.744E-5 | 2 | 39 | 2 | 6292 |
| DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
| DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
| cellular macromolecular complex assembly | 8.3223E-4 | 2 | 182 | 2 | 6292 |
| cellular macromolecular complex subunit organization | 1.6882E-3 | 2 | 259 | 2 | 6292 |
| macromolecular complex assembly | 1.9877E-3 | 2 | 281 | 2 | 6292 |
| macromolecular complex subunit organization | 3.2108E-3 | 2 | 357 | 2 | 6292 |
| cellular component assembly | 3.7349E-3 | 2 | 385 | 2 | 6292 |
| DNA unwinding involved in replication | 4.4455E-3 | 2 | 14 | 1 | 6292 |
| DNA geometric change | 6.3477E-3 | 2 | 20 | 1 | 6292 |
| DNA duplex unwinding | 6.3477E-3 | 2 | 20 | 1 | 6292 |
| DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| ATPase activity | 1.1194E-3 | 2 | 211 | 2 | 6292 |
| nucleoside-triphosphatase activity | 2.7262E-3 | 2 | 329 | 2 | 6292 |
| hydrolase activity, acting on acid anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
| pyrophosphatase activity | 3.1391E-3 | 2 | 353 | 2 | 6292 |
| DNA replication origin binding | 4.1283E-3 | 2 | 13 | 1 | 6292 |
| ATP-dependent DNA helicase activity | 5.7138E-3 | 2 | 18 | 1 | 6292 |