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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.984447079102]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
GPA1
  • endosome
  • heterotrimeric G-protein complex
  • plasma membrane
    		•
  • response to drug
  • heterotrimeric G-protein complex cycle
  • inositol lipid-mediated signaling
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
    		•
  • GTPase activity
    		•
    STE18
  • heterotrimeric G-protein complex
  • cytoplasm
  • plasma membrane
    		•
  • heterotrimeric G-protein complex cycle
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
    		•
  • signal transducer activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    heterotrimeric G-protein complex 1.5158E-7 2 3 2 6292
    extrinsic to plasma membrane 6.8716E-6 2 17 2 6292
    extrinsic to membrane 6.4422E-5 2 51 2 6292
    plasma membrane part 8.0641E-5 2 57 2 6292
    plasma membrane 1.8077E-3 2 268 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    heterotrimeric G-protein complex cycle 1.5158E-7 2 3 2 6292
    purine ribonucleotide catabolic process 5.0527E-7 2 5 2 6292
    ribonucleoside triphosphate catabolic process 5.0527E-7 2 5 2 6292
    purine ribonucleoside triphosphate catabolic process 5.0527E-7 2 5 2 6292
    regulation of nucleotide catabolic process 5.0527E-7 2 5 2 6292
    regulation of GTPase activity 5.0527E-7 2 5 2 6292
    regulation of GTP catabolic process 5.0527E-7 2 5 2 6292
    regulation of purine nucleotide catabolic process 5.0527E-7 2 5 2 6292
    GTP catabolic process 5.0527E-7 2 5 2 6292
    ribonucleotide catabolic process 5.0527E-7 2 5 2 6292
    purine nucleotide catabolic process 5.0527E-7 2 5 2 6292
    purine nucleoside triphosphate catabolic process 5.0527E-7 2 5 2 6292
    regulation of nucleotide metabolic process 1.0611E-6 2 7 2 6292
    GTP metabolic process 1.0611E-6 2 7 2 6292
    nucleoside triphosphate catabolic process 1.0611E-6 2 7 2 6292
    nucleotide catabolic process 1.4147E-6 2 8 2 6292
    regulation of hydrolase activity 1.819E-6 2 9 2 6292
    nucleobase, nucleoside, nucleotide and nucleic acid catabolic process 5.3053E-6 2 15 2 6292
    nucleobase, nucleoside and nucleotide catabolic process 5.3053E-6 2 15 2 6292
    regulation of cellular catabolic process 9.6001E-6 2 20 2 6292
    regulation of catabolic process 1.3945E-5 2 24 2 6292
    cellular nitrogen compound catabolic process 1.3945E-5 2 24 2 6292
    heterocycle catabolic process 1.6421E-5 2 26 2 6292
    regulation of conjugation with cellular fusion by signal transduction 1.7735E-5 2 27 2 6292
    purine ribonucleoside triphosphate metabolic process 1.7735E-5 2 27 2 6292
    pheromone-dependent signal transduction involved in conjugation with cellular fusion 1.7735E-5 2 27 2 6292
    purine nucleoside triphosphate metabolic process 1.7735E-5 2 27 2 6292
    ribonucleoside triphosphate metabolic process 2.0514E-5 2 29 2 6292
    G-protein coupled receptor protein signaling pathway 2.3495E-5 2 31 2 6292
    regulation of multi-organism process 2.5061E-5 2 32 2 6292
    regulation of conjugation 2.5061E-5 2 32 2 6292
    regulation of conjugation with cellular fusion 2.5061E-5 2 32 2 6292
    cell surface receptor linked signaling pathway 2.5061E-5 2 32 2 6292
    nucleoside triphosphate metabolic process 2.8346E-5 2 34 2 6292
    regulation of catalytic activity 4.7798E-5 2 44 2 6292
    regulation of molecular function 4.7798E-5 2 44 2 6292
    purine ribonucleotide metabolic process 6.6999E-5 2 52 2 6292
    ribonucleotide metabolic process 7.5032E-5 2 55 2 6292
    purine nucleotide metabolic process 8.3521E-5 2 58 2 6292
    response to pheromone involved in conjugation with cellular fusion 1.44E-4 2 76 2 6292
    response to pheromone 2.3525E-4 2 97 2 6292
    cellular response to chemical stimulus 2.8654E-4 2 107 2 6292
    small molecule catabolic process 3.9158E-4 2 125 2 6292
    conjugation with cellular fusion 3.9158E-4 2 125 2 6292
    conjugation 3.979E-4 2 126 2 6292
    nucleotide metabolic process 4.1068E-4 2 128 2 6292
    nucleoside phosphate metabolic process 4.1068E-4 2 128 2 6292
    response to organic substance 4.7071E-4 2 137 2 6292
    multi-organism process 5.13E-4 2 143 2 6292
    nucleobase, nucleoside and nucleotide metabolic process 6.1875E-4 2 157 2 6292
    heterocycle metabolic process 7.3441E-4 2 171 2 6292
    signaling pathway 8.5067E-4 2 184 2 6292
    reproductive cellular process 1.1194E-3 2 211 2 6292
    reproductive process 1.1301E-3 2 212 2 6292
    signal transduction 1.1516E-3 2 214 2 6292
    signal transmission 1.1841E-3 2 217 2 6292
    signaling process 1.1841E-3 2 217 2 6292
    sexual reproduction 1.3656E-3 2 233 2 6292
    signaling 1.598E-3 2 252 2 6292
    reproduction 2.7096E-3 2 328 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    response to chemical stimulus 3.6769E-3 2 382 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
    regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
    phosphoinositide-mediated signaling 5.0798E-3 2 16 1 6292
    inositol lipid-mediated signaling 5.0798E-3 2 16 1 6292
    catabolic process 6.2027E-3 2 496 2 6292
    regulation of primary metabolic process 6.6615E-3 2 514 2 6292
    regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
    regulation of metabolic process 7.5452E-3 2 547 2 6292
    second-messenger-mediated signaling 9.5139E-3 2 30 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle