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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.995577963561]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
DRS2
  • trans-Golgi network
    		•
  • phospholipid translocation
  • post-Golgi vesicle-mediated transport
  • intracellular protein transport
  • endocytosis
    		•
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
  • phospholipid-translocating ATPase activity
    		•
    NEO1
  • endosome
  • Golgi membrane
  • Golgi apparatus
  • COPI-coated vesicle
    		•
  • retrograde vesicle-mediated transport, Golgi to ER
  • vacuole organization
  • endocytosis
    		•
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
  • phospholipid-translocating ATPase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Golgi apparatus part 3.5475E-4 2 119 2 6292
    Golgi apparatus 7.3441E-4 2 171 2 6292
    trans-Golgi network 4.1283E-3 2 13 1 6292
    COPI-coated vesicle 6.6645E-3 2 21 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    endocytosis 1.9342E-4 2 88 2 6292
    membrane invagination 2.2085E-4 2 94 2 6292
    Golgi vesicle transport 7.0879E-4 2 168 2 6292
    membrane organization 9.8542E-4 2 198 2 6292
    cellular membrane organization 9.8542E-4 2 198 2 6292
    phospholipid translocation 2.224E-3 2 7 1 6292
    lipid translocation 2.224E-3 2 7 1 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    phospholipid transport 3.811E-3 2 12 1 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    retrograde vesicle-mediated transport, Golgi to ER 8.248E-3 2 26 1 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    phospholipid-translocating ATPase activity 1.819E-6 2 9 2 6292
    phospholipid transporter activity 4.5979E-6 2 14 2 6292
    ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 4.5979E-6 2 14 2 6292
    lipid transporter activity 8.6401E-6 2 19 2 6292
    ATPase activity, coupled to transmembrane movement of ions 2.0514E-5 2 29 2 6292
    primary active transmembrane transporter activity 7.5032E-5 2 55 2 6292
    P-P-bond-hydrolysis-driven transmembrane transporter activity 7.5032E-5 2 55 2 6292
    ATPase activity, coupled to transmembrane movement of substances 7.5032E-5 2 55 2 6292
    hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 7.5032E-5 2 55 2 6292
    ATPase activity, coupled to movement of substances 8.6451E-5 2 59 2 6292
    active transmembrane transporter activity 3.6682E-4 2 121 2 6292
    ion transmembrane transporter activity 5.3483E-4 2 146 2 6292
    ATPase activity, coupled 5.5711E-4 2 149 2 6292
    ATPase activity 1.1194E-3 2 211 2 6292
    substrate-specific transmembrane transporter activity 1.7943E-3 2 267 2 6292
    transmembrane transporter activity 2.3578E-3 2 306 2 6292
    nucleoside-triphosphatase activity 2.7262E-3 2 329 2 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    hydrolase activity, acting on acid anhydrides 3.1391E-3 2 353 2 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.1391E-3 2 353 2 6292
    pyrophosphatase activity 3.1391E-3 2 353 2 6292
    transporter activity 4.1132E-3 2 404 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle