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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.18922048855]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
VMA13
  • vacuolar proton-transporting V-type ATPase, V1 domain
  • fungal-type vacuole membrane
    		•
  • vacuolar acidification
    		•
  • proton-transporting ATPase activity, rotational mechanism
    		•
    VMA7
  • vacuolar proton-transporting V-type ATPase, V1 domain
  • fungal-type vacuole membrane
    		•
  • vacuolar acidification
    		•
  • proton-transporting ATPase activity, rotational mechanism
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    proton-transporting V-type ATPase, V1 domain 1.4147E-6 2 8 2 6292
    vacuolar proton-transporting V-type ATPase, V1 domain 1.4147E-6 2 8 2 6292
    proton-transporting two-sector ATPase complex, catalytic domain 3.9411E-6 2 13 2 6292
    vacuolar proton-transporting V-type ATPase complex 5.3053E-6 2 15 2 6292
    proton-transporting V-type ATPase complex 5.3053E-6 2 15 2 6292
    proton-transporting two-sector ATPase complex 3.0063E-5 2 35 2 6292
    fungal-type vacuole membrane 1.3647E-4 2 74 2 6292
    vacuolar membrane 3.1973E-4 2 113 2 6292
    vacuolar part 3.6682E-4 2 121 2 6292
    fungal-type vacuole 6.2668E-4 2 158 2 6292
    lytic vacuole 6.2668E-4 2 158 2 6292
    storage vacuole 6.2668E-4 2 158 2 6292
    vacuole 1.0983E-3 2 209 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    vacuolar acidification 1.3945E-5 2 24 2 6292
    pH reduction 1.3945E-5 2 24 2 6292
    intracellular pH reduction 1.3945E-5 2 24 2 6292
    regulation of intracellular pH 1.5158E-5 2 25 2 6292
    regulation of cellular pH 1.5158E-5 2 25 2 6292
    regulation of pH 2.0514E-5 2 29 2 6292
    cellular monovalent inorganic cation homeostasis 2.8346E-5 2 34 2 6292
    monovalent inorganic cation homeostasis 3.552E-5 2 38 2 6292
    cellular cation homeostasis 2.7588E-4 2 105 2 6292
    cation homeostasis 2.974E-4 2 109 2 6292
    cellular chemical homeostasis 3.5475E-4 2 119 2 6292
    cellular ion homeostasis 3.5475E-4 2 119 2 6292
    cellular homeostasis 3.6076E-4 2 120 2 6292
    chemical homeostasis 3.791E-4 2 123 2 6292
    ion homeostasis 3.791E-4 2 123 2 6292
    homeostatic process 4.1951E-3 2 408 2 6292
    regulation of biological quality 7.6561E-3 2 551 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    proton-transporting ATPase activity, rotational mechanism 3.9411E-6 2 13 2 6292
    cation-transporting ATPase activity 6.0632E-6 2 16 2 6292
    ATPase activity, coupled to transmembrane movement of ions 2.0514E-5 2 29 2 6292
    hydrogen ion transmembrane transporter activity 7.2304E-5 2 54 2 6292
    primary active transmembrane transporter activity 7.5032E-5 2 55 2 6292
    P-P-bond-hydrolysis-driven transmembrane transporter activity 7.5032E-5 2 55 2 6292
    ATPase activity, coupled to transmembrane movement of substances 7.5032E-5 2 55 2 6292
    hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 7.5032E-5 2 55 2 6292
    monovalent inorganic cation transmembrane transporter activity 8.6451E-5 2 59 2 6292
    ATPase activity, coupled to movement of substances 8.6451E-5 2 59 2 6292
    inorganic cation transmembrane transporter activity 2.5516E-4 2 101 2 6292
    cation transmembrane transporter activity 3.4879E-4 2 118 2 6292
    active transmembrane transporter activity 3.6682E-4 2 121 2 6292
    ion transmembrane transporter activity 5.3483E-4 2 146 2 6292
    ATPase activity, coupled 5.5711E-4 2 149 2 6292
    ATPase activity 1.1194E-3 2 211 2 6292
    substrate-specific transmembrane transporter activity 1.7943E-3 2 267 2 6292
    transmembrane transporter activity 2.3578E-3 2 306 2 6292
    nucleoside-triphosphatase activity 2.7262E-3 2 329 2 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    hydrolase activity, acting on acid anhydrides 3.1391E-3 2 353 2 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.1391E-3 2 353 2 6292
    pyrophosphatase activity 3.1391E-3 2 353 2 6292
    transporter activity 4.1132E-3 2 404 2 6292
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