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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.21772123614]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
KAP122
  • cytoplasm
  • nuclear pore
    		•
  • protein import into nucleus
  • response to drug
  • regulation of cell size
    		•
  • protein transmembrane transporter activity
    		•
    KAP123
  • nucleus
  • cytoplasm
  • nuclear pore
    		•
  • protein import into nucleus
    		•
  • protein transmembrane transporter activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    pore complex 6.6999E-5 2 52 2 6292
    nuclear pore 6.6999E-5 2 52 2 6292
    nuclear envelope 9.9543E-4 2 199 2 6292
    integral to membrane 1.6363E-3 2 255 2 6292
    intrinsic to membrane 1.7276E-3 2 262 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear import 5.6994E-5 2 48 2 6292
    protein localization in nucleus 5.6994E-5 2 48 2 6292
    protein import into nucleus 5.6994E-5 2 48 2 6292
    protein import 2.9194E-4 2 108 2 6292
    nuclear transport 4.2367E-4 2 130 2 6292
    nucleocytoplasmic transport 4.2367E-4 2 130 2 6292
    protein localization in organelle 5.5711E-4 2 149 2 6292
    protein targeting 1.3892E-3 2 235 2 6292
    intracellular protein transport 1.6363E-3 2 255 2 6292
    protein transport 1.8213E-3 2 269 2 6292
    establishment of protein localization 1.8485E-3 2 271 2 6292
    cellular protein localization 1.8898E-3 2 274 2 6292
    cellular macromolecule localization 2.0305E-3 2 284 2 6292
    protein localization 2.3118E-3 2 303 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein transmembrane transporter activity 1.819E-6 2 9 2 6292
    macromolecule transmembrane transporter activity 1.819E-6 2 9 2 6292
    protein transporter activity 8.3521E-5 2 58 2 6292
    substrate-specific transmembrane transporter activity 1.7943E-3 2 267 2 6292
    transmembrane transporter activity 2.3578E-3 2 306 2 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    transporter activity 4.1132E-3 2 404 2 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle