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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.55745956268]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SDH3
  • mitochondrial respiratory chain complex II
  • mitochondrion
    		•
  • tricarboxylic acid cycle
  • mitochondrial electron transport, succinate to ubiquinone
    		•
  • succinate dehydrogenase (ubiquinone) activity
    		•
    SDH4
  • mitochondrial respiratory chain complex II
  • mitochondrion
    		•
  • tricarboxylic acid cycle
  • mitochondrial electron transport, succinate to ubiquinone
    		•
  • succinate dehydrogenase (ubiquinone) activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    respiratory chain complex II 3.0316E-7 2 4 2 6292
    mitochondrial respiratory chain complex II 3.0316E-7 2 4 2 6292
    succinate dehydrogenase complex (ubiquinone) 3.0316E-7 2 4 2 6292
    fumarate reductase complex 3.0316E-7 2 4 2 6292
    succinate dehydrogenase complex 3.0316E-7 2 4 2 6292
    mitochondrial respiratory chain 1.6421E-5 2 26 2 6292
    respiratory chain 1.6421E-5 2 26 2 6292
    mitochondrial membrane part 2.5011E-4 2 100 2 6292
    mitochondrial inner membrane 7.6048E-4 2 174 2 6292
    organelle inner membrane 8.5997E-4 2 185 2 6292
    mitochondrial membrane 1.7808E-3 2 266 2 6292
    mitochondrial envelope 2.4514E-3 2 312 2 6292
    mitochondrial part 5.6881E-3 2 475 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mitochondrial electron transport, succinate to ubiquinone 3.0316E-7 2 4 2 6292
    acetyl-CoA catabolic process 5.3053E-6 2 15 2 6292
    tricarboxylic acid cycle 5.3053E-6 2 15 2 6292
    acetyl-CoA metabolic process 9.6001E-6 2 20 2 6292
    coenzyme catabolic process 9.6001E-6 2 20 2 6292
    cofactor catabolic process 1.1672E-5 2 22 2 6292
    respiratory electron transport chain 1.5158E-5 2 25 2 6292
    electron transport chain 1.5158E-5 2 25 2 6292
    ATP synthesis coupled electron transport 1.5158E-5 2 25 2 6292
    mitochondrial ATP synthesis coupled electron transport 1.5158E-5 2 25 2 6292
    oxidation reduction 1.6421E-5 2 26 2 6292
    oxidative phosphorylation 5.2295E-5 2 46 2 6292
    aerobic respiration 1.7194E-4 2 83 2 6292
    cellular respiration 2.3525E-4 2 97 2 6292
    coenzyme metabolic process 3.6076E-4 2 120 2 6292
    energy derivation by oxidation of organic compounds 5.5711E-4 2 149 2 6292
    cofactor metabolic process 5.9526E-4 2 154 2 6292
    phosphorylation 8.0494E-4 2 179 2 6292
    generation of precursor metabolites and energy 9.5571E-4 2 195 2 6292
    phosphorus metabolic process 1.3191E-3 2 229 2 6292
    phosphate metabolic process 1.3191E-3 2 229 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    catabolic process 6.2027E-3 2 496 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor 5.0527E-7 2 5 2 6292
    succinate dehydrogenase (ubiquinone) activity 5.0527E-7 2 5 2 6292
    succinate dehydrogenase activity 5.0527E-7 2 5 2 6292
    oxidoreductase activity, acting on the CH-CH group of donors 1.3945E-5 2 24 2 6292
    oxidoreductase activity 1.9877E-3 2 281 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle