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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 2.08161601854]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
PAN2
  • PAN complex
  • cytoplasm
    		•
  • mRNA 3'-end processing
  • mRNA processing
  • postreplication repair
    		•
  • poly(A)-specific ribonuclease activity
    		•
    PAN3
  • PAN complex
  • cytoplasm
    		•
  • DNA repair
  • mRNA 3'-end processing
  • postreplication repair
    		•
  • poly(A)-specific ribonuclease activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    PAN complex 5.0527E-8 2 2 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    postreplication repair 7.7306E-6 2 18 2 6292
    mRNA 3'-end processing 2.3495E-5 2 31 2 6292
    RNA 3'-end processing 4.3504E-5 2 42 2 6292
    mRNA processing 6.1087E-4 2 156 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    mRNA metabolic process 1.1408E-3 2 213 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    RNA processing 3.6384E-3 2 380 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    poly(A)-specific ribonuclease activity 5.0527E-8 2 2 2 6292
    3'-5'-exoribonuclease activity 1.2783E-5 2 23 2 6292
    exoribonuclease activity 1.6421E-5 2 26 2 6292
    exoribonuclease activity, producing 5'-phosphomonoesters 1.6421E-5 2 26 2 6292
    exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2.8346E-5 2 34 2 6292
    3'-5' exonuclease activity 3.0063E-5 2 35 2 6292
    exonuclease activity 5.2295E-5 2 46 2 6292
    ribonuclease activity 5.5711E-4 2 149 2 6292
    nuclease activity 9.9543E-4 2 199 2 6292
    hydrolase activity, acting on ester bonds 2.929E-3 2 341 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle