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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 2.75715279304]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
COX1
  • mitochondrion
  • mitochondrial respiratory chain complex IV
    		•
  • mitochondrial electron transport, cytochrome c to oxygen
  • aerobic respiration
    		•
  • cytochrome-c oxidase activity
    		•
    COX2
  • mitochondrion
  • mitochondrial respiratory chain complex IV
    		•
  • mitochondrial electron transport, cytochrome c to oxygen
  • aerobic respiration
    		•
  • cytochrome-c oxidase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mitochondrial respiratory chain complex IV 3.3348E-6 2 12 2 6292
    respiratory chain complex IV 3.3348E-6 2 12 2 6292
    mitochondrial respiratory chain 1.6421E-5 2 26 2 6292
    respiratory chain 1.6421E-5 2 26 2 6292
    mitochondrial membrane part 2.5011E-4 2 100 2 6292
    mitochondrial inner membrane 7.6048E-4 2 174 2 6292
    organelle inner membrane 8.5997E-4 2 185 2 6292
    mitochondrial membrane 1.7808E-3 2 266 2 6292
    mitochondrial envelope 2.4514E-3 2 312 2 6292
    mitochondrial part 5.6881E-3 2 475 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mitochondrial electron transport, cytochrome c to oxygen 2.2737E-6 2 10 2 6292
    respiratory electron transport chain 1.5158E-5 2 25 2 6292
    electron transport chain 1.5158E-5 2 25 2 6292
    ATP synthesis coupled electron transport 1.5158E-5 2 25 2 6292
    mitochondrial ATP synthesis coupled electron transport 1.5158E-5 2 25 2 6292
    oxidation reduction 1.6421E-5 2 26 2 6292
    oxidative phosphorylation 5.2295E-5 2 46 2 6292
    aerobic respiration 1.7194E-4 2 83 2 6292
    cellular respiration 2.3525E-4 2 97 2 6292
    energy derivation by oxidation of organic compounds 5.5711E-4 2 149 2 6292
    phosphorylation 8.0494E-4 2 179 2 6292
    generation of precursor metabolites and energy 9.5571E-4 2 195 2 6292
    phosphorus metabolic process 1.3191E-3 2 229 2 6292
    phosphate metabolic process 1.3191E-3 2 229 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    heme-copper terminal oxidase activity 3.3348E-6 2 12 2 6292
    cytochrome-c oxidase activity 3.3348E-6 2 12 2 6292
    oxidoreductase activity, acting on heme group of donors 3.3348E-6 2 12 2 6292
    oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 3.3348E-6 2 12 2 6292
    hydrogen ion transmembrane transporter activity 7.2304E-5 2 54 2 6292
    monovalent inorganic cation transmembrane transporter activity 8.6451E-5 2 59 2 6292
    inorganic cation transmembrane transporter activity 2.5516E-4 2 101 2 6292
    cation transmembrane transporter activity 3.4879E-4 2 118 2 6292
    ion transmembrane transporter activity 5.3483E-4 2 146 2 6292
    substrate-specific transmembrane transporter activity 1.7943E-3 2 267 2 6292
    oxidoreductase activity 1.9877E-3 2 281 2 6292
    transmembrane transporter activity 2.3578E-3 2 306 2 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    transporter activity 4.1132E-3 2 404 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle