YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Tpk1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BCY1
  • nucleus
  • cytoplasm
  • response to heat
  • signal transduction
  • pseudohyphal growth
  • response to stress
  • cAMP-dependent protein kinase inhibitor activity
  • FET4
  • integral to plasma membrane
  • plasma membrane
  • low-affinity iron ion transport
  • intracellular copper ion transport
  • copper ion import
  • iron ion transmembrane transporter activity
  • copper ion transmembrane transporter activity
  • RIM15
  • nucleus
  • cytoplasm
  • regulation of meiosis
  • protein amino acid phosphorylation
  • age-dependent response to oxidative stress involved in chronological cell aging
  • response to stress
  • protein kinase activity
  • TCP1
  • chaperonin-containing T-complex
  • cytoskeleton
  • cytoplasm
  • cytoskeleton organization
  • protein folding
  • unfolded protein binding
  • TPK1
  • cytoplasm
  • cAMP-dependent protein kinase complex
  • pseudohyphal growth
  • Ras protein signal transduction
  • protein amino acid phosphorylation
  • cAMP-dependent protein kinase activity
  • protein serine/threonine kinase activity
  • TPK2
  • cytoplasm
  • cAMP-dependent protein kinase complex
  • pseudohyphal growth
  • Ras protein signal transduction
  • protein amino acid phosphorylation
  • cAMP-dependent protein kinase activity
  • protein serine/threonine kinase activity
  • TPK3
  • cytoplasm
  • cAMP-dependent protein kinase complex
  • positive regulation of apoptosis
  • pseudohyphal growth
  • protein amino acid phosphorylation
  • cAMP-dependent protein kinase activity
  • protein serine/threonine kinase activity
  • VPS13
  • endosome
  • mitochondrion
  • extrinsic to membrane
  • ascospore formation
  • protein retention in Golgi apparatus
  • late endosome to vacuole transport
  • vacuolar protein catabolic process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cAMP-dependent protein kinase complex 1.3495E-9 8 3 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    pseudohyphal growth 8.4567E-7 8 68 4 6292
    cell growth 1.8936E-6 8 83 4 6292
    filamentous growth of a population of unicellular organisms 2.6235E-6 8 90 4 6292
    growth of unicellular organism as a thread of attached cells 2.6235E-6 8 90 4 6292
    protein amino acid phosphorylation 4.5093E-6 8 103 4 6292
    filamentous growth 5.0588E-6 8 106 4 6292
    regulation of cell size 6.0831E-6 8 111 4 6292
    regulation of anatomical structure size 6.7673E-6 8 114 4 6292
    regulation of cellular component size 6.7673E-6 8 114 4 6292
    growth 1.7632E-5 8 145 4 6292
    phosphorylation 4.0556E-5 8 179 4 6292
    phosphorus metabolic process 1.0663E-4 8 229 4 6292
    phosphate metabolic process 1.0663E-4 8 229 4 6292
    regulation of biological quality 2.2653E-4 8 551 5 6292
    cellular protein metabolic process 4.9998E-4 8 1074 6 6292
    post-translational protein modification 5.9444E-4 8 357 4 6292
    protein metabolic process 6.8696E-4 8 1136 6 6292
    biological regulation 9.9402E-4 8 1213 6 6292
    Ras protein signal transduction 1.1316E-3 8 41 2 6292
    low-affinity iron ion transport 1.2715E-3 8 1 1 6292
    regulation of cellular process 1.2889E-3 8 796 5 6292
    regulation of biological process 1.5139E-3 8 824 5 6292
    signal transduction 1.9142E-3 8 214 3 6292
    signal transmission 1.9926E-3 8 217 3 6292
    signaling process 1.9926E-3 8 217 3 6292
    protein modification process 2.1135E-3 8 499 4 6292
    small GTPase mediated signal transduction 2.7417E-3 8 64 2 6292
    signaling 3.0608E-3 8 252 3 6292
    macromolecule modification 3.4456E-3 8 569 4 6292
    positive regulation of programmed cell death 3.8101E-3 8 3 1 6292
    positive regulation of cell death 3.8101E-3 8 3 1 6292
    positive regulation of apoptosis 3.8101E-3 8 3 1 6292
    regulation of programmed cell death 5.0773E-3 8 4 1 6292
    regulation of cell death 5.0773E-3 8 4 1 6292
    regulation of apoptosis 5.0773E-3 8 4 1 6292
    intracellular copper ion transport 6.3431E-3 8 5 1 6292
    iron ion transmembrane transport 6.3431E-3 8 5 1 6292
    copper ion transmembrane transport 7.6075E-3 8 6 1 6292
    copper ion import 7.6075E-3 8 6 1 6292
    intracellular signal transduction 8.6291E-3 8 115 2 6292
    age-dependent response to oxidative stress 8.8705E-3 8 7 1 6292
    age-dependent response to oxidative stress involved in chronological cell aging 8.8705E-3 8 7 1 6292
    age-dependent general metabolic decline involved in chronological cell aging 8.8705E-3 8 7 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cyclic nucleotide-dependent protein kinase activity 1.3495E-9 8 3 3 6292
    cAMP-dependent protein kinase activity 1.3495E-9 8 3 3 6292
    protein kinase activity 2.3558E-5 8 156 4 6292
    phosphotransferase activity, alcohol group as acceptor 6.0315E-5 8 198 4 6292
    kinase activity 9.4447E-5 8 222 4 6292
    protein serine/threonine kinase activity 1.5553E-4 8 91 3 6292
    transferase activity, transferring phosphorus-containing groups 1.1041E-3 8 420 4 6292
    cAMP-dependent protein kinase inhibitor activity 1.2715E-3 8 1 1 6292
    protein serine/threonine kinase inhibitor activity 5.0773E-3 8 4 1 6292
    copper ion transmembrane transporter activity 6.3431E-3 8 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle