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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rsp5. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ART10
  • cytoplasm
  • biological_process
  • molecular_function
  • BUL1
  • ubiquitin ligase complex
  • plasma membrane
  • mitochondrion inheritance
  • protein polyubiquitination
  • protein monoubiquitination
  • protein binding
  • ubiquitin binding
  • HXT6
  • mitochondrion
  • plasma membrane
  • hexose transport
  • fructose transmembrane transporter activity
  • glucose transmembrane transporter activity
  • mannose transmembrane transporter activity
  • LSB1
  • nucleus
  • cytoplasm
  • biological_process
  • molecular_function
  • PHO84
  • integral to plasma membrane
  • phosphate transport
  • manganese ion transport
  • inorganic phosphate transmembrane transporter activity
  • manganese ion transmembrane transporter activity
  • RNQ1
  • cytosol
  • biological_process
  • molecular_function
  • RPB3
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPB5
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPO21
  • mitochondrion
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPO26
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RSP5
  • ubiquitin ligase complex
  • cytoplasm
  • mitochondrion
  • Golgi apparatus
  • endosome membrane
  • plasma membrane
  • mRNA export from nucleus
  • farnesyl diphosphate biosynthetic process, mevalonate pathway
  • transcription
  • protein polyubiquitination
  • chromatin assembly or disassembly
  • endocytosis
  • protein monoubiquitination
  • ubiquitin-protein ligase activity
  • YKR018C
  • nucleus
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA-directed RNA polymerase II, core complex 3.7251E-9 12 12 4 6292
    DNA-directed RNA polymerase complex 2.3225E-7 12 31 4 6292
    RNA polymerase complex 2.3225E-7 12 31 4 6292
    nuclear DNA-directed RNA polymerase complex 2.3225E-7 12 31 4 6292
    DNA-directed RNA polymerase II, holoenzyme 2.6426E-6 12 56 4 6292
    DNA-directed RNA polymerase I complex 2.9963E-4 12 14 2 6292
    DNA-directed RNA polymerase III complex 4.4637E-4 12 17 2 6292
    nucleoplasm part 8.6718E-4 12 245 4 6292
    nucleoplasm 1.1483E-3 12 264 4 6292
    plasma membrane 1.2148E-3 12 268 4 6292
    ubiquitin ligase complex 2.8832E-3 12 43 2 6292
    nucleolar part 3.1543E-3 12 45 2 6292
    nuclear lumen 8.2402E-3 12 453 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein polyubiquitination 6.8633E-4 12 21 2 6292
    protein monoubiquitination 8.2512E-4 12 23 2 6292
    transcription from RNA polymerase I promoter 1.4082E-3 12 30 2 6292
    farnesyl diphosphate biosynthetic process, mevalonate pathway 1.9072E-3 12 1 1 6292
    transcription from RNA polymerase III promoter 2.2566E-3 12 38 2 6292
    transcription 2.3988E-3 12 552 5 6292
    transcription from RNA polymerase II promoter 2.7777E-3 12 335 4 6292
    terpenoid metabolic process 3.811E-3 12 2 1 6292
    terpenoid biosynthetic process 3.811E-3 12 2 1 6292
    farnesyl diphosphate biosynthetic process 3.811E-3 12 2 1 6292
    farnesyl diphosphate metabolic process 3.811E-3 12 2 1 6292
    prenol metabolic process 5.7116E-3 12 3 1 6292
    prenol biosynthetic process 5.7116E-3 12 3 1 6292
    polyprenol metabolic process 5.7116E-3 12 3 1 6292
    polyprenol biosynthetic process 5.7116E-3 12 3 1 6292
    protein ubiquitination 6.4883E-3 12 65 2 6292
    secondary metabolic process 9.5026E-3 12 5 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA polymerase activity 3.4126E-7 12 34 4 6292
    DNA-directed RNA polymerase activity 3.4126E-7 12 34 4 6292
    nucleotidyltransferase activity 2.0532E-4 12 168 4 6292
    transferase activity, transferring phosphorus-containing groups 6.2986E-3 12 420 4 6292
    inorganic phosphate transmembrane transporter activity 9.5026E-3 12 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle