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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rpc40. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA-directed RNA polymerase I complex 5.3495E-10 7 14 4 6292
RNA polymerase complex 1.6706E-8 7 31 4 6292
nuclear DNA-directed RNA polymerase complex 1.6706E-8 7 31 4 6292
DNA-directed RNA polymerase complex 1.6706E-8 7 31 4 6292
nucleolar part 7.8686E-8 7 45 4 6292
nucleolus 8.0465E-7 7 211 5 6292
nuclear lumen 3.5214E-5 7 453 5 6292
DNA-directed RNA polymerase III complex 1.4316E-4 7 17 2 6292
organelle lumen 2.1944E-4 7 660 5 6292
intracellular organelle lumen 2.1944E-4 7 660 5 6292
membrane-enclosed lumen 2.9135E-4 7 700 5 6292
Golgi-associated vesicle 8.1111E-4 7 40 2 6292
organelle part 8.2061E-4 7 2282 7 6292
intracellular organelle part 8.2061E-4 7 2282 7 6292
non-membrane-bounded organelle 1.3072E-3 7 959 5 6292
intracellular non-membrane-bounded organelle 1.3072E-3 7 959 5 6292
nuclear part 2.5214E-3 7 1103 5 6292
cytoplasmic vesicle 5.6907E-3 7 107 2 6292
membrane-bounded vesicle 5.6907E-3 7 107 2 6292
cytoplasmic membrane-bounded vesicle 5.6907E-3 7 107 2 6292
vesicle 6.0062E-3 7 110 2 6292
Golgi apparatus part 7.0004E-3 7 119 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription from RNA polymerase I promoter 1.4556E-8 7 30 4 6292
intra-Golgi vesicle-mediated transport 2.4252E-4 7 22 2 6292
ribosome biogenesis 2.7556E-4 7 346 4 6292
ribonucleoprotein complex biogenesis 3.725E-4 7 374 4 6292
transcription from RNA polymerase III promoter 7.3181E-4 7 38 2 6292
transcription, DNA-dependent 1.162E-3 7 503 4 6292
RNA biosynthetic process 1.2065E-3 7 508 4 6292
transcription 1.6538E-3 7 552 4 6292
ER to Golgi vesicle-mediated transport 3.4587E-3 7 83 2 6292
cellular component biogenesis 3.9065E-3 7 694 4 6292
nucleic acid metabolic process 7.9545E-3 7 1415 5 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA polymerase activity 2.4595E-8 7 34 4 6292
DNA-directed RNA polymerase activity 2.4595E-8 7 34 4 6292
nucleotidyltransferase activity 1.6125E-5 7 168 4 6292
transferase activity, transferring phosphorus-containing groups 5.8266E-4 7 420 4 6292
GTPase activity 1.8819E-3 7 61 2 6292
transferase activity 6.5162E-3 7 797 4 6292
catalytic activity 7.8491E-3 7 2150 6 6292

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