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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CCT4
  • chaperonin-containing T-complex
  • cytoskeleton
  • cytoplasm
  • cytoskeleton organization
  • protein folding
  • unfolded protein binding
  • CHC1
  • clathrin vesicle coat
  • vesicle-mediated transport
  • endocytosis
  • structural molecule activity
  • COG8
  • Golgi transport complex
  • intra-Golgi vesicle-mediated transport
  • molecular_function
  • GCD1
  • guanyl-nucleotide exchange factor complex
  • eukaryotic translation initiation factor 2B complex
  • regulation of translational initiation
  • translation initiation factor activity
  • guanyl-nucleotide exchange factor activity
  • GCD11
  • multi-eIF complex
  • ribosome
  • eukaryotic translation initiation factor 2 complex
  • translational initiation
  • translation initiation factor activity
  • GCD2
  • guanyl-nucleotide exchange factor complex
  • eukaryotic translation initiation factor 2B complex
  • regulation of translational initiation
  • translation initiation factor activity
  • guanyl-nucleotide exchange factor activity
  • enzyme regulator activity
  • GCD6
  • guanyl-nucleotide exchange factor complex
  • eukaryotic translation initiation factor 2B complex
  • regulation of translational initiation
  • translation initiation factor activity
  • guanyl-nucleotide exchange factor activity
  • GCD7
  • mitochondrion
  • guanyl-nucleotide exchange factor complex
  • eukaryotic translation initiation factor 2B complex
  • regulation of translational initiation
  • translation initiation factor activity
  • guanyl-nucleotide exchange factor activity
  • enzyme regulator activity
  • GCN3
  • guanyl-nucleotide exchange factor complex
  • eukaryotic translation initiation factor 2B complex
  • regulation of translational initiation
  • translation initiation factor activity
  • guanyl-nucleotide exchange factor activity
  • enzyme regulator activity
  • GUT1
  • cytoplasm
  • glycerol metabolic process
  • glycerol kinase activity
  • IST1
  • endosome
  • translation
  • molecular_function
  • PDC1
  • nucleus
  • cytoplasm
  • cytosol
  • pyruvate metabolic process
  • glucose catabolic process to ethanol
  • pyruvate decarboxylase activity
  • PRO1
  • cytoplasm
  • telomere maintenance
  • ribosome biogenesis
  • proline biosynthetic process
  • glutamate 5-kinase activity
  • RRP40
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • ribosome assembly
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RNA binding
  • RRP46
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • SUI2
  • multi-eIF complex
  • cytoplasm
  • ribosome
  • eukaryotic translation initiation factor 2 complex
  • translational initiation
  • translation initiation factor activity
  • SUI3
  • multi-eIF complex
  • ribosome
  • eukaryotic translation initiation factor 2 complex
  • translational initiation
  • translation initiation factor activity
  • XKS1
  • cytoplasm
  • xylulose catabolic process
  • xylulokinase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    eukaryotic translation initiation factor 2B complex 1.0443E-13 18 5 5 6292
    guanyl-nucleotide exchange factor complex 2.1854E-12 18 7 5 6292
    eukaryotic translation initiation factor 2 complex 1.9664E-8 18 3 3 6292
    protein complex 7.1619E-7 18 1137 13 6292
    multi-eIF complex 1.0914E-6 18 8 3 6292
    cytoplasm 3.3277E-5 18 3552 18 6292
    macromolecular complex 5.1941E-5 18 1635 13 6292
    cytoplasmic part 1.7523E-4 18 2482 15 6292
    cytoplasmic exosome (RNase complex) 5.0164E-4 18 12 2 6292
    nuclear exosome (RNase complex) 7.9401E-4 18 15 2 6292
    exosome (RNase complex) 9.059E-4 18 16 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translational initiation 8.1143E-14 18 42 8 6292
    regulation of translational initiation 4.7748E-11 18 11 5 6292
    translation 2.6564E-7 18 376 9 6292
    regulation of translation 3.9966E-7 18 57 5 6292
    posttranscriptional regulation of gene expression 5.6392E-7 18 61 5 6292
    regulation of cellular protein metabolic process 9.7619E-7 18 68 5 6292
    regulation of protein metabolic process 1.4929E-6 18 74 5 6292
    primary metabolic process 1.9624E-4 18 2896 16 6292
    cellular protein metabolic process 2.3461E-4 18 1074 10 6292
    protein metabolic process 3.7892E-4 18 1136 10 6292
    cellular metabolic process 3.8278E-4 18 3033 16 6292
    metabolic process 6.7953E-4 18 3157 16 6292
    cellular process 1.7601E-3 18 4426 18 6292
    cellular macromolecule metabolic process 2.0953E-3 18 2285 13 6292
    cellular macromolecule biosynthetic process 2.7619E-3 18 1187 9 6292
    macromolecule biosynthetic process 2.7957E-3 18 1189 9 6292
    macromolecule metabolic process 2.7988E-3 18 2349 13 6292
    xylulose catabolic process 2.8608E-3 18 1 1 6292
    xylulose metabolic process 2.8608E-3 18 1 1 6292
    gene expression 4.8135E-3 18 1283 9 6292
    cellular biosynthetic process 5.2027E-3 18 1567 10 6292
    biosynthetic process 6.1689E-3 18 1602 10 6292
    regulation of gene expression 6.8545E-3 18 445 5 6292
    regulation of macromolecule biosynthetic process 7.598E-3 18 456 5 6292
    proline biosynthetic process 8.5592E-3 18 3 1 6292
    regulation of cellular biosynthetic process 8.7795E-3 18 472 5 6292
    regulation of biosynthetic process 8.8575E-3 18 473 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation initiation factor activity 1.5591E-15 18 27 8 6292
    translation factor activity, nucleic acid binding 1.215E-13 18 44 8 6292
    guanyl-nucleotide exchange factor activity 4.9512E-8 18 38 5 6292
    GTPase regulator activity 2.8119E-6 18 84 5 6292
    nucleoside-triphosphatase regulator activity 5.1775E-6 18 95 5 6292
    nucleic acid binding 3.185E-5 18 666 9 6292
    enzyme regulator activity 2.2169E-4 18 207 5 6292
    binding 1.1259E-3 18 1294 10 6292
    3'-5'-exoribonuclease activity 1.8874E-3 18 23 2 6292
    exoribonuclease activity, producing 5'-phosphomonoesters 2.4123E-3 18 26 2 6292
    exoribonuclease activity 2.4123E-3 18 26 2 6292
    xylulokinase activity 2.8608E-3 18 1 1 6292
    glycerol kinase activity 2.8608E-3 18 1 1 6292
    glutamate 5-kinase activity 2.8608E-3 18 1 1 6292
    exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4.1079E-3 18 34 2 6292
    3'-5' exonuclease activity 4.3495E-3 18 35 2 6292
    exonuclease activity 7.4266E-3 18 46 2 6292
    amino acid kinase activity 8.5592E-3 18 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle