| From Publication: | Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22. |
| Notes: | From the published set of protein complexes (core proteins only) |
| Complex Size: | 4 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| mitochondrial pyruvate dehydrogenase complex | 2.2991E-13 | 4 | 6 | 4 | 6292 |
| pyruvate dehydrogenase complex | 2.2991E-13 | 4 | 6 | 4 | 6292 |
| mitochondrial matrix | 5.9211E-7 | 4 | 176 | 4 | 6292 |
| mitochondrial lumen | 5.9211E-7 | 4 | 176 | 4 | 6292 |
| mitochondrial part | 3.2102E-5 | 4 | 475 | 4 | 6292 |
| nucleoid | 9.8027E-5 | 4 | 26 | 2 | 6292 |
| mitochondrial nucleoid | 9.8027E-5 | 4 | 26 | 2 | 6292 |
| organelle lumen | 1.2008E-4 | 4 | 660 | 4 | 6292 |
| intracellular organelle lumen | 1.2008E-4 | 4 | 660 | 4 | 6292 |
| membrane-enclosed lumen | 1.5203E-4 | 4 | 700 | 4 | 6292 |
| mitochondrion | 1.0175E-3 | 4 | 1125 | 4 | 6292 |
| protein complex | 1.0617E-3 | 4 | 1137 | 4 | 6292 |
| macromolecular complex | 4.5471E-3 | 4 | 1635 | 4 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| pyruvate metabolic process | 2.0807E-9 | 4 | 44 | 4 | 6292 |
| monocarboxylic acid metabolic process | 1.9682E-7 | 4 | 134 | 4 | 6292 |
| organic acid metabolic process | 7.7123E-6 | 4 | 333 | 4 | 6292 |
| oxoacid metabolic process | 7.7123E-6 | 4 | 333 | 4 | 6292 |
| carboxylic acid metabolic process | 7.7123E-6 | 4 | 333 | 4 | 6292 |
| cellular ketone metabolic process | 8.9951E-6 | 4 | 346 | 4 | 6292 |
| small molecule metabolic process | 2.1139E-4 | 4 | 760 | 4 | 6292 |
| acetyl-CoA biosynthetic process from pyruvate | 1.2712E-3 | 4 | 2 | 1 | 6292 |
| acetyl-CoA biosynthetic process | 2.5411E-3 | 4 | 4 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| pyruvate dehydrogenase (acetyl-transferring) activity | 1.8182E-6 | 4 | 4 | 2 | 6292 |
| pyruvate dehydrogenase activity | 1.8182E-6 | 4 | 4 | 2 | 6292 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 3.0297E-6 | 4 | 5 | 2 | 6292 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors | 9.0505E-5 | 4 | 25 | 2 | 6292 |
| dihydrolipoyllysine-residue acetyltransferase activity | 6.3573E-4 | 4 | 1 | 1 | 6292 |
| dihydrolipoamide S-acyltransferase activity | 6.3573E-4 | 4 | 1 | 1 | 6292 |
| S-acetyltransferase activity | 1.2712E-3 | 4 | 2 | 1 | 6292 |
| S-acyltransferase activity | 8.2408E-3 | 4 | 13 | 1 | 6292 |