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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 23 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
EHD3
  • mitochondrion
  • fatty acid beta-oxidation
  • endocytosis
  • 3-hydroxyisobutyryl-CoA hydrolase activity
  • MRP1
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP13
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP17
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP21
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translational initiation
  • translation
  • structural constituent of ribosome
  • MRP4
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • tRNA binding
  • MRP51
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translational initiation
  • translation
  • structural constituent of ribosome
  • MRPS16
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPS17
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPS18
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPS28
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • MRPS5
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPS8
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPS9
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • NAM9
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • PET123
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM10
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM19
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM22
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM23
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • response to drug
  • translation
  • structural constituent of ribosome
  • RSM25
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM27
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM7
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    organellar small ribosomal subunit 1.0554E-52 23 35 22 6292
    mitochondrial small ribosomal subunit 1.0554E-52 23 35 22 6292
    small ribosomal subunit 1.8223E-43 23 73 22 6292
    organellar ribosome 3.7782E-41 23 90 22 6292
    mitochondrial ribosome 3.7782E-41 23 90 22 6292
    mitochondrial matrix 3.986E-34 23 176 22 6292
    mitochondrial lumen 3.986E-34 23 176 22 6292
    ribosomal subunit 9.9181E-34 23 183 22 6292
    ribosome 4.0193E-29 23 290 22 6292
    mitochondrial part 2.7928E-24 23 475 22 6292
    ribonucleoprotein complex 1.6356E-23 23 514 22 6292
    organelle lumen 4.3267E-21 23 660 22 6292
    intracellular organelle lumen 4.3267E-21 23 660 22 6292
    membrane-enclosed lumen 1.6006E-20 23 700 22 6292
    mitochondrion 5.2909E-18 23 1125 23 6292
    non-membrane-bounded organelle 1.7059E-17 23 959 22 6292
    intracellular non-membrane-bounded organelle 1.7059E-17 23 959 22 6292
    macromolecular complex 2.077E-12 23 1635 22 6292
    cytoplasmic part 4.8015E-10 23 2482 23 6292
    organelle part 2.8812E-9 23 2282 22 6292
    intracellular organelle part 2.8812E-9 23 2282 22 6292
    cytoplasm 1.8846E-6 23 3552 23 6292
    membrane-bounded organelle 7.4929E-6 23 3771 23 6292
    intracellular membrane-bounded organelle 7.4929E-6 23 3771 23 6292
    intracellular organelle 4.3548E-5 23 4070 23 6292
    organelle 4.3795E-5 23 4071 23 6292
    intracellular part 3.7561E-3 23 4938 23 6292
    intracellular 4.4613E-3 23 4975 23 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.4531E-26 23 376 22 6292
    cellular protein metabolic process 2.0721E-16 23 1074 22 6292
    protein metabolic process 7.1268E-16 23 1136 22 6292
    cellular macromolecule biosynthetic process 1.8717E-15 23 1187 22 6292
    macromolecule biosynthetic process 1.9423E-15 23 1189 22 6292
    gene expression 1.0325E-14 23 1283 22 6292
    cellular biosynthetic process 8.2187E-13 23 1567 22 6292
    biosynthetic process 1.3312E-12 23 1602 22 6292
    cellular macromolecule metabolic process 2.964E-9 23 2285 22 6292
    macromolecule metabolic process 5.3764E-9 23 2349 22 6292
    primary metabolic process 1.6931E-8 23 2896 23 6292
    cellular metabolic process 4.9214E-8 23 3033 23 6292
    metabolic process 1.241E-7 23 3157 23 6292
    cellular process 3.0112E-4 23 4426 23 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 3.026E-32 23 212 22 6292
    structural molecule activity 1.3957E-27 23 339 22 6292
    3-hydroxyisobutyryl-CoA hydrolase activity 3.6554E-3 23 1 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle