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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 8 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

Arp2/3 protein complex 2.2792E-18 8 7 6 6292
actin cytoskeleton 1.3939E-10 8 85 6 6292
cytoskeletal part 2.3858E-10 8 201 7 6292
cytoskeleton 3.9693E-10 8 216 7 6292
non-membrane-bounded organelle 1.3016E-5 8 959 7 6292
intracellular non-membrane-bounded organelle 1.3016E-5 8 959 7 6292
protein complex 4.178E-5 8 1137 7 6292
macromolecular complex 4.9027E-4 8 1635 7 6292
organelle part 4.4856E-3 8 2282 7 6292
intracellular organelle part 4.4856E-3 8 2282 7 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitochondrion inheritance 1.5374E-13 8 29 6 6292
mitochondrion distribution 1.5374E-13 8 29 6 6292
mitochondrion localization 1.9212E-13 8 30 6 6292
organelle localization 5.0591E-13 8 85 7 6292
organelle inheritance 2.2752E-12 8 44 6 6292
actin cytoskeleton organization 7.9902E-10 8 113 6 6292
actin filament-based process 9.88E-10 8 117 6 6292
mitochondrion organization 5.6755E-9 8 156 6 6292
cytoskeleton organization 6.0485E-8 8 231 6 6292
cellular localization 8.2414E-7 8 643 7 6292
actin filament organization 8.4567E-7 8 68 4 6292
localization 2.5864E-5 8 1060 7 6292
organelle organization 6.5677E-4 8 1127 6 6292
actin nucleation 3.8101E-3 8 3 1 6292
cellular component organization 4.336E-3 8 1582 6 6292
microtubule-based process 8.0573E-3 8 111 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

structural constituent of cytoskeleton 3.0642E-7 8 53 4 6292
structural molecule activity 5.984E-7 8 339 6 6292
actin binding 2.9353E-4 8 21 2 6292
ATP binding 3.8504E-4 8 24 2 6292
adenyl ribonucleotide binding 4.1826E-4 8 25 2 6292
adenyl nucleotide binding 6.0455E-4 8 30 2 6292
purine nucleoside binding 6.4583E-4 8 31 2 6292
nucleoside binding 6.8844E-4 8 32 2 6292
ribonucleotide binding 1.1316E-3 8 41 2 6292
purine ribonucleotide binding 1.1316E-3 8 41 2 6292
purine nucleotide binding 1.8172E-3 8 52 2 6292
nucleotide binding 2.3343E-3 8 59 2 6292
cytoskeletal protein binding 2.3343E-3 8 59 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle