From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.085] [SVM Score: 0.433855997175] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
RIF1 |
|
|
|
SMC2 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
nuclear condensin complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
condensin complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
telomere cap complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
nuclear telomere cap complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
nuclear chromosome, telomeric region | 7.2981E-3 | 2 | 23 | 1 | 6292 |
chromosome, telomeric region | 8.5646E-3 | 2 | 27 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitotic chromosome condensation | 3.4937E-3 | 2 | 11 | 1 | 6292 |
chromosome condensation | 4.1283E-3 | 2 | 13 | 1 | 6292 |
telomere maintenance via telomere lengthening | 4.1283E-3 | 2 | 13 | 1 | 6292 |
telomere maintenance via telomerase | 4.1283E-3 | 2 | 13 | 1 | 6292 |
RNA-dependent DNA replication | 4.1283E-3 | 2 | 13 | 1 | 6292 |
chromosome organization | 7.7677E-3 | 2 | 555 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
sequence-specific DNA binding | 6.1895E-5 | 2 | 50 | 2 | 6292 |
AT DNA binding | 9.5344E-4 | 2 | 3 | 1 | 6292 |
DNA binding | 1.6492E-3 | 2 | 256 | 2 | 6292 |
DNA secondary structure binding | 2.859E-3 | 2 | 9 | 1 | 6292 |
telomeric DNA binding | 3.811E-3 | 2 | 12 | 1 | 6292 |
double-stranded DNA binding | 7.2981E-3 | 2 | 23 | 1 | 6292 |