| From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
| Notes: | Classifier used Gene Ontology annotations. [FDR: 0.084] [SVM Score: 0.474872212616] |
| Complex Size: | 2 proteins |
| Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
| HEK2 |
|
|
|
| RIF1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| nuclear chromosome, telomeric region | 1.2783E-5 | 2 | 23 | 2 | 6292 |
| chromosome, telomeric region | 1.7735E-5 | 2 | 27 | 2 | 6292 |
| nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
| nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
| chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
| chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
| telomere cap complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
| nuclear telomere cap complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| telomere maintenance via telomere lengthening | 3.9411E-6 | 2 | 13 | 2 | 6292 |
| telomere maintenance via telomerase | 3.9411E-6 | 2 | 13 | 2 | 6292 |
| RNA-dependent DNA replication | 3.9411E-6 | 2 | 13 | 2 | 6292 |
| DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
| anatomical structure homeostasis | 2.0592E-3 | 2 | 286 | 2 | 6292 |
| telomere organization | 2.0592E-3 | 2 | 286 | 2 | 6292 |
| telomere maintenance | 2.0592E-3 | 2 | 286 | 2 | 6292 |
| intracellular mRNA localization | 3.1764E-3 | 2 | 10 | 1 | 6292 |
| homeostatic process | 4.1951E-3 | 2 | 408 | 2 | 6292 |
| regulation of biological quality | 7.6561E-3 | 2 | 551 | 2 | 6292 |
| chromosome organization | 7.7677E-3 | 2 | 555 | 2 | 6292 |
| DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| telomeric DNA binding | 3.811E-3 | 2 | 12 | 1 | 6292 |