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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.084] [SVM Score: 0.490222402146]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

endoplasmic reticulum membrane 4.4352E-4 2 133 2 6292
endoplasmic reticulum part 5.6464E-4 2 150 2 6292
subsynaptic reticulum 5.6464E-4 2 150 2 6292
nuclear membrane-endoplasmic reticulum network 1.3539E-3 2 232 2 6292
translocon complex 1.5888E-3 2 5 1 6292
Sec61 translocon complex 1.5888E-3 2 5 1 6292
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex 2.5415E-3 2 8 1 6292
endoplasmic reticulum 3.3381E-3 2 364 2 6292
rough endoplasmic reticulum 3.811E-3 2 12 1 6292
rough endoplasmic reticulum membrane 3.811E-3 2 12 1 6292
endomembrane system 3.9918E-3 2 398 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

posttranslational protein targeting to membrane, translocation 1.2712E-3 2 4 1 6292
posttranslational protein targeting to membrane 2.859E-3 2 9 1 6292
SRP-dependent cotranslational protein targeting to membrane, translocation 3.4937E-3 2 11 1 6292
SRP-dependent cotranslational protein targeting to membrane 6.6645E-3 2 21 1 6292
cotranslational protein targeting to membrane 7.6148E-3 2 24 1 6292
GPI anchor biosynthetic process 8.8811E-3 2 28 1 6292
phosphoinositide biosynthetic process 9.1975E-3 2 29 1 6292
GPI anchor metabolic process 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

GTPase regulator activity 1.7614E-4 2 84 2 6292
nucleoside-triphosphatase regulator activity 2.256E-4 2 95 2 6292
GTPase inhibitor activity 9.5344E-4 2 3 1 6292
enzyme regulator activity 1.0773E-3 2 207 2 6292
ARF guanyl-nucleotide exchange factor activity 1.9064E-3 2 6 1 6292
enzyme inhibitor activity 8.5646E-3 2 27 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle