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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.543915673023]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
POL30
  • replication fork
  • PCNA complex
  • nucleus
    		•
  • mutagenesis
  • lagging strand elongation
  • base-excision repair
  • leading strand elongation
  • nucleotide-excision repair
  • mismatch repair
  • chromatin silencing at silent mating-type cassette
  • chromatin silencing at telomere
  • postreplication repair
    		•
  • DNA polymerase processivity factor activity
    		•
    RFC4
  • DNA replication factor C complex
    		•
  • sister chromatid cohesion
  • leading strand elongation
  • mismatch repair
    		•
  • DNA clamp loader activity
  • purine nucleotide binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    replication fork 4.3504E-5 2 42 2 6292
    PCNA complex 3.1786E-4 2 1 1 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292
    DNA replication factor C complex 3.4937E-3 2 11 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    leading strand elongation 5.3053E-6 2 15 2 6292
    mismatch repair 1.7735E-5 2 27 2 6292
    DNA strand elongation 2.3495E-5 2 31 2 6292
    DNA strand elongation involved in DNA replication 2.3495E-5 2 31 2 6292
    DNA-dependent DNA replication 1.678E-4 2 82 2 6292
    DNA replication 3.791E-4 2 123 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    mutagenesis 2.859E-3 2 9 1 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    base-excision repair 3.811E-3 2 12 1 6292
    postreplication repair 5.7138E-3 2 18 1 6292
    lagging strand elongation 5.7138E-3 2 18 1 6292
    response to stress 6.2277E-3 2 497 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA polymerase processivity factor activity 3.1786E-4 2 1 1 6292
    protein-DNA loading ATPase activity 2.224E-3 2 7 1 6292
    DNA clamp loader activity 2.224E-3 2 7 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle