From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.632933669151] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
SCF ubiquitin ligase complex | 2.779E-6 | 2 | 11 | 2 | 6292 |
cullin-RING ubiquitin ligase complex | 4.5979E-6 | 2 | 14 | 2 | 6292 |
ubiquitin ligase complex | 4.5626E-5 | 2 | 43 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
protein ubiquitination | 1.051E-4 | 2 | 65 | 2 | 6292 |
protein modification by small protein conjugation | 1.8468E-4 | 2 | 86 | 2 | 6292 |
protein modification by small protein conjugation or removal | 3.2544E-4 | 2 | 114 | 2 | 6292 |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.224E-3 | 2 | 7 | 1 | 6292 |
post-translational protein modification | 3.2108E-3 | 2 | 357 | 2 | 6292 |
protein ubiquitination during ubiquitin-dependent protein catabolic process | 3.4937E-3 | 2 | 11 | 1 | 6292 |
protein modification process | 6.278E-3 | 2 | 499 | 2 | 6292 |
macromolecule modification | 8.1649E-3 | 2 | 569 | 2 | 6292 |
G2/M transition of mitotic cell cycle | 9.1975E-3 | 2 | 29 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA replication origin binding | 3.9411E-6 | 2 | 13 | 2 | 6292 |
sequence-specific DNA binding | 6.1895E-5 | 2 | 50 | 2 | 6292 |
DNA binding | 1.6492E-3 | 2 | 256 | 2 | 6292 |
protein binding, bridging | 6.3477E-3 | 2 | 20 | 1 | 6292 |