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Protein Overview: UBX5

General Information:
Name(s) found: UBX5 / YDR330W [SGD]
Description(s) found:
Found 32 descriptions.
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  • UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 500 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: ubiquitin-dependent protein catabolic process [IEPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEGKVDEFM AITGADDAAI ATQFIEMADG NLNTAISLFF ENGGAALLSS NNTPTPSNST  60
   61 PMAPTSVDSD ADAQLAERLQ REAYQQQQPD QDYVRPPDEA RHEVLTETSG FPISYGGIGG 120
  121 RFEPLHRVND MFDEGRPESI FNQRLDDTNT NTYINDNSSD SLDSEEENDD DEYEYVEEPV 180
  181 IELDEDGNIK EYTKLVRKPK TISKEQKLAL LFRPPFSIMS KLDLDAAKQK ARAKQKWIMI 240
  241 NIQDSGIFQC QALNRDLWSS RPVKTIIKEN FVFLQYQYES RNAQPYLQFY HLNNKDDLPH 300
  301 IAILDPITGE RVKQWNRVVP IPEQFISEIN EFLASFSLDP KVPNPTVNEP LPKVDPTTLT 360
  361 EEQQMELAIK ESLNNNSSKS NQEEVPSTGE EQKRVQEPDP FSTIEARVHP EPPNKPGITT 420
  421 RIQIRTGDGS RLVRRFNALE DTVRTIYEVI KTEMDGFADS RFTLNDHQRE DLIDKLNMTI 480
  481 ADAGLKNSSL LLEKLDPEIE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BFA1 CDC48 DOA1 FBP1 MRM1 NDT80 NPL4 OTU1 RDS2 SHP1 TEM1 TUP1 UBX4 UBX5 UBX7 UFD1 UFD2 YDR049W YGL108C YJR098C YNL155W YOR342C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data UBX5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] deduced N/A No confident structure predictions are available.
    2 View Details [203..354] MSA 1.046973 View MSA. No confident structure predictions are available.
    3 View Details [355..500] PSI-BLAST 19.221849 p47
    4 View Details [383..500] PSI-BLAST 20.39794 Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • binding
    		•  0.665189138843282 bayes_pls_golite062009
  • hydrolase activity
    		•  0.150237022038507 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.13699526678272 bayes_pls_golite062009
    4
    Term Confidence Notes
  • binding
    		•  2.19381585790185 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.83465130904364 bayes_pls_golite062009
  • protein binding
    		•  1.17197911794381 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.16468510691469 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.919595189902044 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.383121378043805 bayes_pls_golite062009
  • hydrolase activity
    		•  0.247201449341942 bayes_pls_golite062009
  • DNA binding
    		•  0.0840213088061073 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0485636215870291 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle