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Protein Overview: UBX4

General Information:
Name(s) found: UBX4 / YMR067C [SGD]
Description(s) found:
Found 23 descriptions.
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  • UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 416 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: sporulation resulting in formation of a cellular spore [IMPLink to PubMed article]
    ubiquitin-dependent protein catabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPMVTVKYNF QLFKCKVSLN STLNDVLHQS IQFFQLHTSS NDWSLIHLDK PVPLDLPWRL  60
   61 LNLPTGVNLE LSKSSNFPVA NKTNREDIPF NTIKIRFQIP GRDSVVKEMP SDQPIAPILR 120
  121 QMSGAAGDDF KIQVFSKIIE FKTIKDENLT LENLGIQEPS SVRLIFNNTS HSEGISANSA 180
  181 IHPKQTPPTM TNPETVASLP PHELHKPSVF LPSDEPLAVI KDQIEDEEDY ELTVEQAKKY 240
  241 QKMLSSKAGT LGGPILTKRL REQSANNLPK KNKAISECLL RVKFPDRSHI QIAFKPNEDM 300
  301 RTVYNVVSQF LIDENMPFTL NQSHPFKPLA KDDKKLLDDL EFGSKTMLLF ETNSNSNGPL 360
  361 IKAHLLEDAQ KITHETRTTP SVNTINKSNP QGPSDNATSI KKTLNRVPKW MKLSKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BFA1 CDC48 DOA1 FBP1 MRM1 NDT80 NPL4 OTU1 RDS2 SHP1 TEM1 TUP1 UBX4 UBX5 UBX7 UFD1 UFD2 YDR049W YGL108C YJR098C YNL155W YOR342C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data UBX4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] deduced N/A No confident structure predictions are available.
    2 View Details [127..225] MSA 3.117997 View MSA. No confident structure predictions are available.
    3 View Details [226..416] PSI-BLAST 17.522879 p47

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.11588141989606 bayes_pls_golite062009
  • protein binding
    		•  1.75262085947538 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.64626529520014 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.03640529353043 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.778769490362734 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.406724367405638 bayes_pls_golite062009
  • hydrolase activity
    		•  0.266557627363523 bayes_pls_golite062009
  • DNA binding
    		•  0.102021710653816 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0672274772804511 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.19381585790185 bayes_pls_golite062009
  • protein binding
    		•  1.89134588490127 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.83465130904364 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.16468510691469 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.919595189902044 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.383121378043805 bayes_pls_golite062009
  • hydrolase activity
    		•  0.247201449341942 bayes_pls_golite062009
  • DNA binding
    		•  0.0840213088061073 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0485636215870291 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle