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Protein Overview: akt-1

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

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[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..452] PSI-BLAST 55.522879 CHICKEN SRC TYROSINE KINASE
2 View Details [453..541] PSI-BLAST 102.0 No description for 2jdoA was found.

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
  • 5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
  • 5.4586557943719 bayes_pls_golite062009
  • kinase activity
  • 5.3287080791198 bayes_pls_golite062009
  • cyclic nucleotide-dependent protein kinase activity
  • 4.97855712164511 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 4.96052051118534 bayes_pls_golite062009
  • cAMP-dependent protein kinase activity
  • 4.66277812893755 bayes_pls_golite062009
  • protein serine/threonine kinase activity
  • 4.46381887831481 bayes_pls_golite062009
  • transferase activity
  • 3.97138602499442 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
  • 3.41480681854114 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
  • 3.40140621607334 bayes_pls_golite062009
  • protein tyrosine kinase activity
  • 2.8153155526437 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
  • 2.79505438761262 bayes_pls_golite062009
  • binding
  • 2.74863538127007 bayes_pls_golite062009
  • transmembrane receptor activity
  • 2.59526003830791 bayes_pls_golite062009
  • ion transmembrane transporter activity
  • 2.52531786618214 bayes_pls_golite062009
  • cation transmembrane transporter activity
  • 2.46424348876434 bayes_pls_golite062009
  • signal transducer activity
  • 2.40586892801446 bayes_pls_golite062009
  • molecular transducer activity
  • 2.40586892801446 bayes_pls_golite062009
  • receptor activity
  • 2.39311927684508 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
  • 2.37122853419919 bayes_pls_golite062009
  • protein binding
  • 2.276111749106 bayes_pls_golite062009
  • cytoskeletal protein binding
  • 2.12615078788254 bayes_pls_golite062009
  • receptor signaling protein activity
  • 2.10379226653669 bayes_pls_golite062009
  • ATP binding
  • 1.97600611746091 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
  • 1.94085498993561 bayes_pls_golite062009
  • adenyl ribonucleotide binding
  • 1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
  • 1.90928021591891 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
  • 1.9016235206634 bayes_pls_golite062009
  • actin binding
  • 1.87817875565699 bayes_pls_golite062009
  • acetylcholine receptor activator activity
  • 1.83545227594542 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
  • 1.81249386965144 bayes_pls_golite062009
  • molecular adaptor activity
  • 1.81145713371725 bayes_pls_golite062009
  • small conjugating protein ligase activity
  • 1.74206248731815 bayes_pls_golite062009
  • purine ribonucleotide binding
  • 1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
  • 1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
  • 1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
  • 1.63195828048121 bayes_pls_golite062009
  • insulin receptor substrate binding
  • 1.62657794525303 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
  • 1.59474164216385 bayes_pls_golite062009
  • JUN kinase kinase kinase kinase activity
  • 1.55257528159541 bayes_pls_golite062009
  • growth factor binding
  • 1.53863828216563 bayes_pls_golite062009
  • phosphoinositide 3-kinase activity
  • 1.5013287968167 bayes_pls_golite062009
  • 1-phosphatidylinositol-3-kinase activity
  • 1.43713739644553 bayes_pls_golite062009
  • MAP kinase kinase activity
  • 1.42275431028856 bayes_pls_golite062009
  • PTB domain binding
  • 1.33588583294761 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
  • 1.32254739984688 bayes_pls_golite062009
  • kinase binding
  • 1.26086833316556 bayes_pls_golite062009
  • ErbB-3 class receptor binding
  • 1.25765701903393 bayes_pls_golite062009
  • epidermal growth factor receptor binding
  • 1.24312972088703 bayes_pls_golite062009
  • acid-amino acid ligase activity
  • 1.2266791546014 bayes_pls_golite062009
  • catalytic activity
  • 1.21655087018101 bayes_pls_golite062009
  • transcription regulator activity
  • 1.16307073947901 bayes_pls_golite062009
  • type II transforming growth factor beta receptor binding
  • 1.15601343883601 bayes_pls_golite062009
  • tubulin binding
  • 1.13686658158825 bayes_pls_golite062009
  • transporter activity
  • 1.11833481501707 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
  • 1.10045286406485 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
  • 1.10045286406485 bayes_pls_golite062009
  • nucleic acid binding
  • 1.06086848160606 bayes_pls_golite062009
  • protein kinase binding
  • 1.06030596516506 bayes_pls_golite062009
  • cation channel activity
  • 1.04999722123563 bayes_pls_golite062009
  • phosphoinositide 3-kinase regulator activity
  • 1.03150090191995 bayes_pls_golite062009
  • DNA binding
  • 1.02122968429273 bayes_pls_golite062009
  • transmembrane transporter activity
  • 0.97575992765505 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
  • 0.959360414036299 bayes_pls_golite062009
  • telethonin binding
  • 0.953133636042811 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
  • 0.872782211382796 bayes_pls_golite062009
  • protein binding, bridging
  • 0.83823250804321 bayes_pls_golite062009
  • transcription factor activity
  • 0.825932471558326 bayes_pls_golite062009
  • MAP kinase activity
  • 0.81943579965027 bayes_pls_golite062009
  • actin filament binding
  • 0.794152600084 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
  • 0.770658204347392 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
  • 0.75189004129952 bayes_pls_golite062009
  • transcription activator activity
  • 0.746097961522136 bayes_pls_golite062009
  • microtubule binding
  • 0.734274677384472 bayes_pls_golite062009
  • fibroblast growth factor binding
  • 0.728507215600658 bayes_pls_golite062009
  • sequence-specific DNA binding
  • 0.716038067837188 bayes_pls_golite062009
  • substrate-specific transporter activity
  • 0.705905455086486 bayes_pls_golite062009
  • vinculin binding
  • 0.666656406096231 bayes_pls_golite062009
  • structural constituent of cytoskeleton
  • 0.612883428421652 bayes_pls_golite062009
  • insulin receptor activity
  • 0.585036697436369 bayes_pls_golite062009
  • transcription repressor activity
  • 0.568332175782799 bayes_pls_golite062009
  • ErbB-2 class receptor binding
  • 0.547121592096699 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
  • 0.537170519944039 bayes_pls_golite062009
  • activin binding
  • 0.510364757301021 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
  • 0.48345772948903 bayes_pls_golite062009
  • enzyme binding
  • 0.46284745266176 bayes_pls_golite062009
  • protein kinase C activity
  • 0.41587987561486 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
  • 0.406297251827056 bayes_pls_golite062009
  • magnesium ion binding
  • 0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
  • 0.37115026509016 bayes_pls_golite062009
  • phosphotyrosine binding
  • 0.311079584914389 bayes_pls_golite062009
  • channel activity
  • 0.287189255116606 bayes_pls_golite062009
  • passive transmembrane transporter activity
  • 0.287189255116606 bayes_pls_golite062009
  • insulin receptor binding
  • 0.266450215230107 bayes_pls_golite062009
  • substrate-specific channel activity
  • 0.261869836686301 bayes_pls_golite062009
  • ion channel activity
  • 0.241519346930618 bayes_pls_golite062009
  • protein complex binding
  • 0.239339759110451 bayes_pls_golite062009
  • SH2 domain binding
  • 0.226760162354251 bayes_pls_golite062009
  • insulin binding
  • 0.147382876071569 bayes_pls_golite062009
  • peptide binding
  • 0.118578378753757 bayes_pls_golite062009
  • alpha-actinin binding
  • 0.0923798087054641 bayes_pls_golite062009
  • JUN kinase kinase kinase activity
  • 0.0613131034808199 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
  • 0.0506751594607393 bayes_pls_golite062009
  • MAP kinase kinase kinase kinase activity
  • 0.01826424351081 bayes_pls_golite062009
  • nitric-oxide synthase regulator activity
  • 0.00407218246327123 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
  • 0.0040394359628233 bayes_pls_golite062009
    2 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle