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Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells. Catalysis of the transfer of a specific substance or related group of substances from the outside of a cell to the inside across a membrane. Catalysis of the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane. Enables the directed movement of vitamins into, out of, within or between cells. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Enables the transfer of a substance from one side of a membrane to the other. Enables the directed movement of a neurotransmitter into, out of, within or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics. Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient. Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. Catalysis of the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis. Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other. Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane. Enables the directed movement of a drug from one side of a membrane to the other. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: transmembrane transporter activity
Acc: GO:0022857
Aspect: Molecular Function
Desc: Enables the transfer of a substance from one side of a membrane to the other.
Synonyms:
  • GO:0005386
  • GO:0015646
Proteins in PDR annotated with:
   This term: 183 [Search]
   Term or descendants: 8700 [Refine Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0022857 - transmembrane transporter activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle