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Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. The binding activity of a molecule that brings together two or more molecules, permitting those molecules to function in a coordinated way. Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68). The molecular function that accepts an input of one form and creates an output of a different form. Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell. Interacting selectively and non-covalently with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: SH3/SH2 adaptor activity
Acc: GO:0005070
Aspect: Molecular Function
Desc: Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).
Synonyms:
  • SH3/SH2 adaptor protein activity
Proteins in PDR annotated with:
   This term: 45 [Search]
   Term or descendants: 45 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005070 - SH3/SH2 adaptor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle