Protein Overview: CG9143-PA

General Information:
Name(s) found:	CG9143-PA / FBpp0085616 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7302399\|gb\|AAF57487.1\| CG9143 [Drosophila melanogaster] [NCBI NR] gi\|33636633\|gb\|AAQ23614.1\| LD11580p [Drosophila melanogaster] [NCBI NR] gi\|20130173\|ref\|NP_611467.1\| CG9143 [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\CG9143 (CG9143, FBgn0034496). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16163475..16166501. It has the cytological map location 56F14-56F15. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding; ATP-dependent RNA helicase activity. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG9143-PA translation from_gene[CG9143 CG9143 FBgn0034496] seq_release:3 mol_weight=91576 cds_boundaries:(2R:15,339,861..15,342,534[-]) aa_length:813 transcript_info:[CG9143-RA seq_release:3] gene_info:[gene symbol:CG9143 FBgn0034496 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] (Q9V915) CG9143 protein [DrosMelano7227.FASTAC.txt] (AE003792) CG9143 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG9143-PA [Drosophila melanogaster]gi\|33636633\|gb\|AAQ23614.1\| LD11580p [Drosophila melanogaster]gi\|20130173\|ref\|NP_611467.1\| CG9143-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:complement(16163651..16163909,16163972..16164155,16164214..16164666,16164724..16164843,16164902..16166327); ID=FBpp0085616; name=CG9143-PA; parent=FBgn0034496,FBtr0086304; dbxref=FlyBase:FBpp0085616,FlyBase_Annotation_IDs:CG9143-PA,GB [fly-100309-contam.fasta] CG9143-PA [Drosophila melanogaster] [nr-271106-contam.fasta] LD11580p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:complement(16163651..16163909,16163972..16164155,16164214..16164666,16164724..16164843,16164902..16166327); ID=FBpp0085616; name=CG9143-PA; parent=FBgn0034496,FBtr0086304; dbxref=FlyBase:FBpp0085616,FlyBase_Annotation_IDs:CG9143-PA,GB_protein:AAF57487.1,REFSEQ:NP_611467,GB_protein:AAF57487; MD5=95663e93fb1c0e5c122427f5ae8f9aa6; length=813; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:complement(16163651..16163909,16163972..16164155,16164214..16164666,16164724..16164843,16164902..16166327); ID=FBpp0085616; name=CG9143-PA; parent=FBgn0034496,FBtr0086304; dbxref=FlyBase:FBpp0085616,FlyBase_Annotation_IDs:CG9143-PA,GB_protein:AAF57487.1,REFSEQ:NP_611467,GB_protein:AAF57487; MD5=95663e93fb1c0e5c122427f5ae8f9aa6; length=813; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] CG9143 OS=Drosophila melanogaster GN=CG9143 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:complement(16163651..16163909,16163972..16164155,16164214..16164666,16164724..16164843,16164902..16166327); ID=FBpp0085616; name=CG9143-PA; parent=FBgn0034496,FBtr0086304; dbxref=FlyBase:FBpp0085616,FlyBase_Annotation_IDs:CG9143-PA,GB_protein:AAF57487.1,REFSEQ:NP_611467,GB_protein:AAF57487,FlyMine:FBpp0085616,modMine:FBpp0085616; MD5=95663e93fb1c0e5c122427f5ae8f9aa6; length=813; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] CG9143 OS=Drosophila melanogaster GN=CG9143 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=2R:complement(join(20277397..20278822,20277219..20277338,20276709..20277161,20276467..20276650,20276146..20276404)); ID=FBpp0085616; name=CG9143-PA; parent=FBgn0034496,FBtr0086304; dbxref=FlyBase:FBpp0085616,FlyBase_Annotation_IDs:CG9143-PA,GB_protein:AAF57487.1,REFSEQ:NP_611467,GB_protein:AAF57487,FlyMine:FBpp0085616,modMine:FBpp0085616; MD5=95663e93fb1c0e5c122427f5ae8f9aa6; length=813; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:complement(join(20277397..20278822,20277219..20277338,20276709..20277161,20276467..20276650,20276146..20276404)); ID=FBpp0085616; name=CG9143-PA; parent=FBgn0034496,FBtr0086304; dbxref=FlyBase:FBpp0085616,FlyBase_Annotation_IDs:CG9143-PA,GB_protein:AAF57487.1,REFSEQ:NP_611467,GB_protein:AAF57487,FlyMine:FBpp0085616,modMine:FBpp0085616; MD5=95663e93fb1c0e5c122427f5ae8f9aa6; length=813; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0085616 type=protein; loc=2R:complement(join(20277397..20278822,20277219..20277338,20276709..20277161,20276467..20276650,20276146..20276404)); ID=FBpp0085616; name=CG9143-PA; parent=FBgn0034496,FBtr0086304; dbxref=FlyBase:FBpp0085616,FlyBase_Annotation_IDs:CG9143-PA,GB_protein:AAF57487.1,REFSEQ:NP_611467,GB_protein:AAF57487,FlyMine:FBpp0085616,modMine:FBpp0085616; MD5=95663e93fb1c0e5c122427f5ae8f9aa6; length=813; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:complement(join(20277397..20278822,20277219..20277338,20276709..20277161,20276467..20276650,20276146..20276404)); ID=FBpp0085616; name=CG9143-PA; parent=FBgn0034496,FBtr0086304; dbxref=FlyBase:FBpp0085616,FlyBase_Annotation_IDs:CG9143-PA,GB_protein:AAF57487.1,REFSEQ:NP_611467,GB_protein:AAF57487,UniProt/TrEMBL:Q6NQY9,FlyMine:FBpp0085616,modMine:FBpp0085616; MD5=95663e93fb1c0e5c122427f5ae8f9aa6; length=813; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	813 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	ATP binding [IEA] mRNA binding [ISS] ATP-dependent RNA helicase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQNKQKTAK PPKLLKGAAK EPALSKAENW QKVKIKGHVI SDDGGGFEGL IGLEVLKDYD  60
   61 ASLVKSSQKR TTSRNPDRER KLKKKKRKVS KGDEEESSES SSESESEDEV AVAARTSKKA 120
  121 RLAERHAQKM QKLREKREKR KELRKQKKSK GKENDNSEES SDEHAADRFA LLRPPPSDDE 180
  181 EEVVKAEDSA DQQESTDEEA PELVPISTGE AEDMSAWNGL GVPASILRAL GEQGFKTPTQ 240
  241 IQALTLPAAI HGKKDILGAA ETGSGKTLAF GIPMLAGIME LKQRNIRSGI RKAPKVKGQQ 300
  301 PEPAADEHEL TPPPEELDHV SGASDEESDA EEQAQRVQTP LYGLVLTPTR ELAVQVKNHL 360
  361 VAAAKYTGIR VAAIFGGLAV AKQERVLRQC PDIVVATPGR LWELYAQGNR HLGKIEDVSF 420
  421 LVIDETDRMV EKGHFEELRS LLKVLNSDEQ KKHQRQNFVY SATLTLVHDL PDHMQKRNVG 480
  481 KRPKFVKQTV DQKIESLIEE LGISQPKIVD ITSSQQTAQT LTESRLLCPI DHKDYHLYYF 540
  541 IQRHPGRTIV FCNSIDCVKR LATLFGLLDC NPLPLHANMI QKQRLKNLER FRDSPTGLLI 600
  601 ATDVAARGLD IPNVEHVIHY QVPRTSENYV HRSGRTARAN KHGITVMFME PGEVKSYVKL 660
  661 YKTLERTEDL PLFPILERFM GAVRERVNLA RDLDKEELKL KRVQSERGWM KKHAEEMDMI 720
  721 IDGYNDESGS DQDEDPFVIE RRRNRLRVET VRAQLNALLA QPIFPRGFSF KYPNSEAAQL 780
  781 ATSHTQSAVE TMKAAIEDQK QAKKDRNKRK RNA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..101]	deduced	N/A	No confident structure predictions are available.
2	View Details	[102..268]	PSI-BLAST	93.0	No description for 2db3A was found.
3	View Details	[269..411]	PSI-BLAST	35.522879	No description for 2gxqA was found.
4	View Details	[412..813]	PSI-BLAST	22.522879	Nucleotide excision repair enzyme UvrB

Functions predicted (by domain):

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
hydrogen ion transmembrane transporter activity	9.07129841752891	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	8.58358908736821	bayes_pls_golite062009
translation initiation factor activity	7.79457008386475	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	7.35625288284796	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	6.62734320850541	bayes_pls_golite062009
translation factor activity, nucleic acid binding	4.98637553020315	bayes_pls_golite062009
translation regulator activity	4.94658029227343	bayes_pls_golite062009
	4.704140727858	bayes_pls_golite062009
structural constituent of ribosome	4.56509805974548	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	4.03326929098701	bayes_pls_golite062009
hydrolase activity	3.63069754092699	bayes_pls_golite062009
structural molecule activity	3.58406348799895	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.4837867129694	bayes_pls_golite062009
ion transmembrane transporter activity	3.35436118751376	bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism	3.28373827150339	bayes_pls_golite062009
DNA clamp loader activity	3.22518920754305	bayes_pls_golite062009
protein-DNA loading ATPase activity	3.19273435123154	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
cation transmembrane transporter activity	3.08390071341252	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
motor activity	2.79327761685782	bayes_pls_golite062009
microtubule motor activity	2.74365461017633	bayes_pls_golite062009
DNA-dependent ATPase activity	2.72462789867829	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
nucleic acid binding	2.51683451033161	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
cation-transporting ATPase activity	2.31476707827367	bayes_pls_golite062009
RNA binding	2.29590582680214	bayes_pls_golite062009
DNA helicase activity	2.2817164193758	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.18118655708491	bayes_pls_golite062009
RNA cap binding	2.17871969124431	bayes_pls_golite062009
DNA binding	2.12258000781149	bayes_pls_golite062009
transcription regulator activity	2.09345198747025	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
ATP-dependent DNA helicase activity	1.88455339138556	bayes_pls_golite062009
helicase activity	1.70242731830224	bayes_pls_golite062009
RNA helicase activity	1.42791449104435	bayes_pls_golite062009
cytoskeletal protein binding	1.40488517180956	bayes_pls_golite062009
RNA-dependent ATPase activity	1.39335733374328	bayes_pls_golite062009
ATP-dependent RNA helicase activity	1.36724390116598	bayes_pls_golite062009
voltage-gated cation channel activity	1.3493704216639	bayes_pls_golite062009
DNA strand annealing activity	1.30936388901516	bayes_pls_golite062009
telomeric DNA binding	1.28350783207533	bayes_pls_golite062009
structure-specific DNA binding	1.2539059700735	bayes_pls_golite062009
protein transporter activity	1.25342367751911	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.23799860254751	bayes_pls_golite062009
voltage-gated ion channel activity	1.23468617030519	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
voltage-gated channel activity	1.216998547662	bayes_pls_golite062009
potassium channel activity	1.20877745413881	bayes_pls_golite062009
ATP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
purine NTP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
double-stranded DNA binding	1.117585097627	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
tubulin binding	0.979946830272106	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.971476020912368	bayes_pls_golite062009
signal transducer activity	0.952448314982579	bayes_pls_golite062009
molecular transducer activity	0.952448314982579	bayes_pls_golite062009
cation channel activity	0.940476916156422	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
DNA polymerase activity	0.928091843881235	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
microtubule binding	0.907162506177187	bayes_pls_golite062009
transcription factor activity	0.887108427603557	bayes_pls_golite062009
actin binding	0.883285269827407	bayes_pls_golite062009
transcription repressor activity	0.862685397469217	bayes_pls_golite062009
ion channel activity	0.848261056209476	bayes_pls_golite062009
channel activity	0.806331380134838	bayes_pls_golite062009
passive transmembrane transporter activity	0.806331380134838	bayes_pls_golite062009
substrate-specific channel activity	0.799997700906738	bayes_pls_golite062009
mRNA binding	0.76699944561918	bayes_pls_golite062009
transcription elongation regulator activity	0.752795599437554	bayes_pls_golite062009
ribonuclease activity	0.712344060953362	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	0.69784475011795	bayes_pls_golite062009
peptidase activity	0.654073677905812	bayes_pls_golite062009
gated channel activity	0.650050847753837	bayes_pls_golite062009
single-stranded DNA binding	0.568457189190858	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	0.563503770238611	bayes_pls_golite062009
GTPase activity	0.437665353870877	bayes_pls_golite062009
anion transmembrane transporter activity	0.43332053110728	bayes_pls_golite062009
snRNA binding	0.418985924846052	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.347363231484033	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.328170855722634	bayes_pls_golite062009
mismatched DNA binding	0.31144582840038	bayes_pls_golite062009
receptor activity	0.277332279568238	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.243902356228423	bayes_pls_golite062009
transmembrane receptor activity	0.243026482777117	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.226231702119567	bayes_pls_golite062009
microfilament motor activity	0.10236059675512	bayes_pls_golite062009
protein transmembrane transporter activity	0.0378638259240902	bayes_pls_golite062009
signal sequence binding	6.53725193420218E-4	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: CG9143-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: