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Protein Overview: RAD2

Protein Complex Data

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
View Run BOI1 Sample boi1 with gst from october 2005 McCusker D, et al (2007)
View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data RAD2 Huh WK, et al. (2003)

Protein Structure Data


[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..195] ORFEUS 12.55 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
2 View Details [196..647] MSA 32.249997 View MSA. No confident structure predictions are available.
3 View Details [648..1031] PSI-BLAST 166.9897 Flap endonuclease-1 (Fen-1 nuclease)
4 View Details [671..1031] PSI-BLAST 72.522879 Crystal structure of the human FEN1-PCNA complex

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • single-stranded DNA specific endodeoxyribonuclease activity
  • 8.219187336366 bayes_pls_golite062009
  • endodeoxyribonuclease activity
  • 7.26787266873051 bayes_pls_golite062009
  • deoxyribonuclease activity
  • 6.75316483671775 bayes_pls_golite062009
  • endonuclease activity
  • 6.39053146471031 bayes_pls_golite062009
  • exonuclease activity
  • 3.46607201774246 bayes_pls_golite062009
  • flap endonuclease activity
  • 3.35117165021395 bayes_pls_golite062009
  • DNA binding
  • 2.74395891269151 bayes_pls_golite062009
  • hydrolase activity
  • 2.60874360745066 bayes_pls_golite062009
  • binding
  • 2.58539672241253 bayes_pls_golite062009
  • nucleic acid binding
  • 2.54722210455433 bayes_pls_golite062009
  • 5'-3' exonuclease activity
  • 2.50129811584994 bayes_pls_golite062009
  • nuclease activity
  • 2.49612885073648 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  • 2.20867470281829 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
  • 2.11221521670814 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
  • 2.01491211227289 bayes_pls_golite062009
  • exodeoxyribonuclease activity
  • 2.00804590500192 bayes_pls_golite062009
  • damaged DNA binding
  • 1.82833131243547 bayes_pls_golite062009
  • 5'-3' exodeoxyribonuclease activity
  • 1.59902329953921 bayes_pls_golite062009
  • structure-specific DNA binding
  • 1.57088273902548 bayes_pls_golite062009
  • double-stranded DNA specific exodeoxyribonuclease activity
  • 1.46817649825808 bayes_pls_golite062009
  • catalytic activity
  • 1.27951740231695 bayes_pls_golite062009
  • 5'-flap endonuclease activity
  • 1.13738790511505 bayes_pls_golite062009
  • single-stranded DNA specific exodeoxyribonuclease activity
  • 1.06918533266108 bayes_pls_golite062009
  • double-stranded DNA binding
  • 0.550147498650064 bayes_pls_golite062009
  • single-stranded DNA specific 5'-3' exodeoxyribonuclease activity
  • 0.496731274592508 bayes_pls_golite062009
  • endodeoxyribonuclease activity, producing 5'-phosphomonoesters
  • 0.330551387282259 bayes_pls_golite062009
  • protein binding
  • 0.235717056815183 bayes_pls_golite062009
  • 3'-5' exonuclease activity
  • 0.175191448555725 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  • 0.0756835782024594 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
  • 0.00167240601151697 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • single-stranded DNA specific endodeoxyribonuclease activity
  • 8.51020676030278 bayes_pls_golite062009
  • endodeoxyribonuclease activity
  • 7.84678654948641 bayes_pls_golite062009
  • deoxyribonuclease activity
  • 7.26876236760767 bayes_pls_golite062009
  • endonuclease activity
  • 6.8680936339396 bayes_pls_golite062009
  • flap endonuclease activity
  • 4.10438637013244 bayes_pls_golite062009
  • exonuclease activity
  • 3.99717729574528 bayes_pls_golite062009
  • 5'-3' exonuclease activity
  • 3.19536858640519 bayes_pls_golite062009
  • nuclease activity
  • 2.9643999717473 bayes_pls_golite062009
  • DNA binding
  • 2.84879111682833 bayes_pls_golite062009
  • hydrolase activity
  • 2.80884894948531 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  • 2.66071760609476 bayes_pls_golite062009
  • nucleic acid binding
  • 2.62833003756567 bayes_pls_golite062009
  • binding
  • 2.59149897255998 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
  • 2.50398903419616 bayes_pls_golite062009
  • exodeoxyribonuclease activity
  • 2.49591627688404 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
  • 2.45364009363271 bayes_pls_golite062009
  • 5'-3' exodeoxyribonuclease activity
  • 2.26658239783943 bayes_pls_golite062009
  • damaged DNA binding
  • 2.10834170214137 bayes_pls_golite062009
  • double-stranded DNA specific exodeoxyribonuclease activity
  • 2.09057967200253 bayes_pls_golite062009
  • 5'-flap endonuclease activity
  • 1.81850767854435 bayes_pls_golite062009
  • structure-specific DNA binding
  • 1.70042864382698 bayes_pls_golite062009
  • single-stranded DNA specific exodeoxyribonuclease activity
  • 1.61167902830399 bayes_pls_golite062009
  • catalytic activity
  • 1.37534898662234 bayes_pls_golite062009
  • single-stranded DNA specific 5'-3' exodeoxyribonuclease activity
  • 1.15948049342759 bayes_pls_golite062009
  • endodeoxyribonuclease activity, producing 5'-phosphomonoesters
  • 0.901965019685213 bayes_pls_golite062009
  • double-stranded DNA binding
  • 0.626785110524684 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  • 0.512509234493511 bayes_pls_golite062009
  • 3'-5' exonuclease activity
  • 0.50487165366129 bayes_pls_golite062009
  • protein binding
  • 0.236485289446406 bayes_pls_golite062009
  • single-stranded DNA specific 3'-5' exodeoxyribonuclease activity
  • 0.14861832363159 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
  • 0.0941467407417242 bayes_pls_golite062009
  • DNA polymerase activity
  • 0.0691107435153178 bayes_pls_golite062009
  • 3'-5'-exodeoxyribonuclease activity
  • 0.0205129272358 bayes_pls_golite062009




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle