YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Tem1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 18 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC15
  • cellular bud neck
  • spindle pole body
  • regulation of exit from mitosis
  • cytokinesis
  • protein amino acid phosphorylation
  • protein kinase activity
  • CDC33
  • nucleus
  • eukaryotic translation initiation factor 4F complex
  • cytoplasm
  • ribosome
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • translational initiation
  • translation initiation factor activity
  • COF1
  • actin cortical patch
  • actin filament severing
  • actin filament depolymerization
  • actin filament organization
  • protein binding
  • COR1
  • mitochondrion
  • mitochondrial respiratory chain complex III
  • aerobic respiration
  • ubiquinol-cytochrome-c reductase activity
  • CPR1
  • nucleus
  • mitochondrion
  • histone deacetylase complex
  • ascospore formation
  • protein metabolic process
  • peptidyl-prolyl cis-trans isomerase activity
  • CPR3
  • mitochondrion
  • protein folding
  • peptidyl-prolyl cis-trans isomerase activity
  • CYS4
  • cytoplasm
  • mitochondrion
  • response to drug
  • cysteine biosynthetic process
  • cystathionine beta-synthase activity
  • DUG2
  • nucleus
  • cytoplasm
  • glutathione catabolic process
  • X-His dipeptidase activity
  • DUT1
  • nucleus
  • cytoplasm
  • pyrimidine deoxyribonucleoside triphosphate catabolic process
  • dUTP diphosphatase activity
  • GUS1
  • cytoplasm
  • methionyl glutamyl tRNA synthetase complex
  • glutamyl-tRNA aminoacylation
  • glutamate-tRNA ligase activity
  • KGD1
  • mitochondrial matrix
  • mitochondrial oxoglutarate dehydrogenase complex
  • mitochondrion
  • mitochondrial nucleoid
  • tricarboxylic acid cycle
  • 2-oxoglutarate metabolic process
  • oxoglutarate dehydrogenase (succinyl-transferring) activity
  • PFK1
  • 6-phosphofructokinase complex
  • cytoplasm
  • mitochondrion
  • glycolysis
  • 6-phosphofructokinase activity
  • SEC53
  • cytosol
  • protein targeting to ER
  • phosphomannomutase activity
  • TEF4
  • mitochondrion
  • ribosome
  • eukaryotic translation elongation factor 1 complex
  • translational elongation
  • translation elongation factor activity
  • TEM1
  • spindle pole body
  • regulation of exit from mitosis
  • protein binding
  • GTPase activity
  • TIF1, TIF2
  • plasma membrane enriched fraction
  • eukaryotic translation initiation factor 4F complex
  • cytoplasm
  • ribosome
  • regulation of translation
  • translational initiation
  • regulation of translational initiation
  • translation
  • nucleotide binding
  • nucleic acid binding
  • translation initiation factor activity
  • ATP binding
  • RNA binding
  • ATP-dependent helicase activity
  • helicase activity
  • ATP-dependent RNA helicase activity
  • hydrolase activity
  • TMA29
  • nucleus
  • cytoplasm
  • ribosome
  • metabolic process
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
  • YGR066C
  • cellular_component
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    eukaryotic translation initiation factor 4F complex 4.6226E-5 18 4 2 6292
    cytoplasmic part 1.7523E-4 18 2482 15 6292
    cytoplasm 4.9756E-4 18 3552 17 6292
    plasma membrane enriched fraction 2.8608E-3 18 1 1 6292
    non-membrane-bounded organelle 2.9714E-3 18 959 8 6292
    intracellular non-membrane-bounded organelle 2.9714E-3 18 959 8 6292
    6-phosphofructokinase complex 5.7138E-3 18 2 1 6292
    ribosome 8.0989E-3 18 290 4 6292
    mitochondrial oxoglutarate dehydrogenase complex 8.5592E-3 18 3 1 6292
    oxoglutarate dehydrogenase complex 8.5592E-3 18 3 1 6292
    protein complex 8.7384E-3 18 1137 8 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    coenzyme catabolic process 1.4247E-3 18 20 2 6292
    cofactor catabolic process 1.7262E-3 18 22 2 6292
    exit from mitosis 2.2305E-3 18 25 2 6292
    regulation of exit from mitosis 2.2305E-3 18 25 2 6292
    pyrimidine deoxyribonucleoside triphosphate catabolic process 2.8608E-3 18 1 1 6292
    pyrimidine deoxyribonucleotide catabolic process 2.8608E-3 18 1 1 6292
    actin filament severing 2.8608E-3 18 1 1 6292
    pyrimidine nucleoside triphosphate catabolic process 2.8608E-3 18 1 1 6292
    pyrimidine nucleotide catabolic process 2.8608E-3 18 1 1 6292
    small molecule catabolic process 5.022E-3 18 125 3 6292
    deoxyribonucleoside triphosphate catabolic process 5.7138E-3 18 2 1 6292
    cysteine biosynthetic process 5.7138E-3 18 2 1 6292
    pyrimidine deoxyribonucleoside triphosphate metabolic process 5.7138E-3 18 2 1 6292
    deoxyribonucleotide catabolic process 5.7138E-3 18 2 1 6292
    2-oxoglutarate metabolic process 5.7138E-3 18 2 1 6292
    translational initiation 6.2199E-3 18 42 2 6292
    deoxyribonucleoside metabolic process 8.5592E-3 18 3 1 6292
    glutamyl-tRNA aminoacylation 8.5592E-3 18 3 1 6292
    pyrimidine deoxyribonucleoside metabolic process 8.5592E-3 18 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation factor activity, nucleic acid binding 2.42E-4 18 44 3 6292
    isomerase activity 6.3791E-4 18 61 3 6292
    cis-trans isomerase activity 6.8931E-4 18 14 2 6292
    peptidyl-prolyl cis-trans isomerase activity 6.8931E-4 18 14 2 6292
    catalytic activity 1.096E-3 18 2150 13 6292
    oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.2305E-3 18 25 2 6292
    translation initiation factor activity 2.6008E-3 18 27 2 6292
    phosphomannomutase activity 2.8608E-3 18 1 1 6292
    cystathionine beta-synthase activity 2.8608E-3 18 1 1 6292
    dUTP diphosphatase activity 2.8608E-3 18 1 1 6292
    oxoglutarate dehydrogenase (succinyl-transferring) activity 5.7138E-3 18 2 1 6292
    6-phosphofructokinase activity 5.7138E-3 18 2 1 6292
    X-His dipeptidase activity 5.7138E-3 18 2 1 6292
    glutamate-tRNA ligase activity 8.5592E-3 18 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle