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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CTF18
  • mitochondrion
  • DNA replication factor C complex
  • mitotic sister chromatid cohesion
  • molecular_function
  • CTF8
  • DNA replication factor C complex
  • mitotic sister chromatid cohesion
  • telomere maintenance
  • response to DNA damage stimulus
  • molecular_function
  • DPB2
  • replication fork
  • nucleus
  • cytoplasm
  • epsilon DNA polymerase complex
  • lagging strand elongation
  • leading strand elongation
  • nucleotide-excision repair
  • mismatch repair
  • DNA binding
  • nucleotidyltransferase activity
  • DNA-directed DNA polymerase activity
  • double-stranded DNA binding
  • transferase activity
  • ELG1
  • nucleus
  • cytoplasm
  • mitochondrion
  • DNA replication factor C complex
  • DNA replication
  • double-strand break repair via homologous recombination
  • telomere maintenance
  • negative regulation of transposition, DNA-mediated
  • negative regulation of DNA recombination
  • molecular_function
  • OLA1
  • cytoplasm
  • biological_process
  • molecular_function
  • POL2
  • replication fork
  • epsilon DNA polymerase complex
  • lagging strand elongation
  • leading strand elongation
  • nucleotide-excision repair
  • mismatch repair
  • DNA synthesis involved in DNA repair
  • chromatin silencing at telomere
  • nucleotide binding
  • nucleic acid binding
  • DNA binding
  • zinc ion binding
  • DNA-directed DNA polymerase activity
  • nucleotidyltransferase activity
  • metal ion binding
  • double-stranded DNA binding
  • transferase activity
  • RFC1
  • DNA replication factor C complex
  • DNA repair
  • leading strand elongation
  • mismatch repair
  • DNA clamp loader activity
  • RFC2
  • DNA replication factor C complex
  • sister chromatid cohesion
  • cell cycle checkpoint
  • leading strand elongation
  • mismatch repair
  • DNA clamp loader activity
  • purine nucleotide binding
  • RFC3
  • nucleus
  • DNA replication factor C complex
  • sister chromatid cohesion
  • leading strand elongation
  • mismatch repair
  • ATPase activity
  • DNA clamp loader activity
  • RFC4
  • DNA replication factor C complex
  • sister chromatid cohesion
  • leading strand elongation
  • mismatch repair
  • DNA clamp loader activity
  • purine nucleotide binding
  • RFC5
  • DNA replication factor C complex
  • sister chromatid cohesion
  • leading strand elongation
  • mismatch repair
  • DNA clamp loader activity
  • TOP2
  • nucleus
  • mitochondrion
  • synaptonemal complex
  • reciprocal meiotic recombination
  • DNA strand elongation involved in DNA replication
  • regulation of mitotic recombination
  • chromatin assembly or disassembly
  • DNA topological change
  • DNA topoisomerase (ATP-hydrolyzing) activity
  • VPS13
  • endosome
  • mitochondrion
  • extrinsic to membrane
  • ascospore formation
  • protein retention in Golgi apparatus
  • late endosome to vacuole transport
  • vacuolar protein catabolic process
  • molecular_function
  • YMR181C
  • cellular_component
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA replication factor C complex 8.1485E-21 14 11 8 6292
    replication fork 5.4337E-20 14 42 10 6292
    chromosomal part 5.6814E-14 14 237 11 6292
    chromosome 2.8457E-13 14 274 11 6292
    non-membrane-bounded organelle 2.2878E-7 14 959 11 6292
    intracellular non-membrane-bounded organelle 2.2878E-7 14 959 11 6292
    protein complex 1.7681E-5 14 1137 10 6292
    epsilon DNA polymerase complex 4.5804E-5 14 5 2 6292
    DNA polymerase complex 2.0481E-4 14 10 2 6292
    macromolecular complex 4.733E-4 14 1635 10 6292
    nuclear replisome 6.8931E-4 14 18 2 6292
    replisome 6.8931E-4 14 18 2 6292
    nuclear replication fork 8.5383E-4 14 20 2 6292
    nucleotide-excision repair complex 9.4251E-4 14 21 2 6292
    organelle part 1.5376E-3 14 2282 11 6292
    intracellular organelle part 1.5376E-3 14 2282 11 6292
    protein-DNA complex 6.8428E-3 14 57 2 6292
    nuclear chromosome part 7.7152E-3 14 190 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    leading strand elongation 2.8384E-16 14 15 7 6292
    DNA strand elongation 3.8301E-16 14 31 8 6292
    DNA strand elongation involved in DNA replication 3.8301E-16 14 31 8 6292
    mismatch repair 3.8713E-14 14 27 7 6292
    DNA replication 5.7293E-13 14 123 9 6292
    DNA-dependent DNA replication 1.6567E-12 14 82 8 6292
    sister chromatid cohesion 3.0766E-11 14 32 6 6292
    response to DNA damage stimulus 2.1491E-10 14 236 9 6292
    cellular response to stress 1.3578E-9 14 290 9 6292
    DNA repair 1.67E-9 14 192 8 6292
    cellular response to stimulus 1.4551E-8 14 379 9 6292
    DNA metabolic process 3.1831E-8 14 585 10 6292
    response to stress 1.5605E-7 14 497 9 6292
    chromosome segregation 1.6567E-7 14 128 6 6292
    response to stimulus 6.3646E-6 14 766 9 6292
    chromosome organization 6.4889E-6 14 555 8 6292
    cell cycle process 3.5254E-5 14 490 7 6292
    cell cycle 5.5258E-5 14 525 7 6292
    nucleic acid metabolic process 1.3057E-4 14 1415 10 6292
    cellular macromolecule biosynthetic process 2.3557E-4 14 1187 9 6292
    macromolecule biosynthetic process 2.3877E-4 14 1189 9 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.2334E-4 14 1566 10 6292
    regulation of DNA recombination 4.7486E-4 14 15 2 6292
    lagging strand elongation 6.8931E-4 14 18 2 6292
    cellular nitrogen compound metabolic process 9.4656E-4 14 1770 10 6292
    nitrogen compound metabolic process 1.0483E-3 14 1791 10 6292
    organelle organization 1.1158E-3 14 1127 8 6292
    mitotic sister chromatid cohesion 1.1326E-3 14 23 2 6292
    cellular macromolecule metabolic process 1.557E-3 14 2285 11 6292
    macromolecule metabolic process 2.0248E-3 14 2349 11 6292
    regulation of DNA metabolic process 2.0606E-3 14 31 2 6292
    cellular biosynthetic process 2.0687E-3 14 1567 9 6292
    biosynthetic process 2.4458E-3 14 1602 9 6292
    nucleotide-excision repair 3.0877E-3 14 38 2 6292
    DNA synthesis involved in DNA repair 8.8726E-3 14 4 1 6292
    mitotic sister chromatid segregation 9.0921E-3 14 66 2 6292
    sister chromatid segregation 9.9063E-3 14 69 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA clamp loader activity 5.1118E-13 14 7 5 6292
    protein-DNA loading ATPase activity 5.1118E-13 14 7 5 6292
    DNA binding 1.6374E-8 14 256 8 6292
    DNA-dependent ATPase activity 7.9952E-8 14 55 5 6292
    ATPase activity, coupled 1.1735E-5 14 149 5 6292
    nucleic acid binding 2.5401E-5 14 666 8 6292
    ATPase activity 6.3238E-5 14 211 5 6292
    nucleotide binding 2.6493E-4 14 59 3 6292
    nucleoside-triphosphatase activity 5.1308E-4 14 329 5 6292
    hydrolase activity, acting on acid anhydrides 7.0976E-4 14 353 5 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 7.0976E-4 14 353 5 6292
    pyrophosphatase activity 7.0976E-4 14 353 5 6292
    double-stranded DNA binding 1.1326E-3 14 23 2 6292
    DNA topoisomerase (ATP-hydrolyzing) activity 2.225E-3 14 1 1 6292
    binding 2.858E-3 14 1294 8 6292
    structure-specific DNA binding 4.1234E-3 14 44 2 6292
    purine nucleotide binding 5.7214E-3 14 52 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle