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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 9 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

eukaryotic translation initiation factor 4F complex 1.9313E-12 9 4 4 6292
mRNA cap binding complex 5.4528E-6 9 3 2 6292
RNA cap binding complex 2.7204E-5 9 6 2 6292
ribonucleoprotein complex 3.4079E-4 9 514 5 6292
ribosome 4.634E-4 9 290 4 6292
plasma membrane enriched fraction 1.4304E-3 9 1 1 6292
macromolecular complex 1.7084E-3 9 1635 7 6292
protein complex 1.7541E-3 9 1137 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

translation 8.3629E-8 9 376 7 6292
translational initiation 2.1099E-7 9 42 4 6292
regulation of translation 7.375E-7 9 57 4 6292
posttranscriptional regulation of gene expression 9.7183E-7 9 61 4 6292
regulation of cellular protein metabolic process 1.5098E-6 9 68 4 6292
regulation of protein metabolic process 2.125E-6 9 74 4 6292
gene expression 2.1668E-5 9 1283 8 6292
negative regulation of translation 3.8057E-5 9 7 2 6292
cellular protein metabolic process 1.0846E-4 9 1074 7 6292
protein metabolic process 1.5759E-4 9 1136 7 6292
negative regulation of cellular protein metabolic process 1.8916E-4 9 15 2 6292
cellular macromolecule biosynthetic process 2.1089E-4 9 1187 7 6292
macromolecule biosynthetic process 2.1326E-4 9 1189 7 6292
negative regulation of protein metabolic process 2.1602E-4 9 16 2 6292
cellular biosynthetic process 1.2993E-3 9 1567 7 6292
biosynthetic process 1.4983E-3 9 1602 7 6292
cellular macromolecule metabolic process 1.8315E-3 9 2285 8 6292
macromolecule metabolic process 2.2547E-3 9 2349 8 6292
regulation of gene expression 2.3358E-3 9 445 4 6292
regulation of macromolecule biosynthetic process 2.5574E-3 9 456 4 6292
regulation of cellular biosynthetic process 2.9058E-3 9 472 4 6292
regulation of biosynthetic process 2.9286E-3 9 473 4 6292
regulation of macromolecule metabolic process 3.2863E-3 9 488 4 6292
regulation of primary metabolic process 3.9771E-3 9 514 4 6292
regulation of cellular metabolic process 4.6362E-3 9 536 4 6292
regulation of metabolic process 4.9926E-3 9 547 4 6292
cellular copper ion homeostasis 9.9746E-3 9 7 1 6292
copper ion homeostasis 9.9746E-3 9 7 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

translation initiation factor activity 3.3401E-8 9 27 4 6292
translation factor activity, nucleic acid binding 2.5557E-7 9 44 4 6292
nucleic acid binding 1.1464E-3 9 666 5 6292
translation initiation factor binding 1.4304E-3 9 1 1 6292
eukaryotic initiation factor 4E binding 1.4304E-3 9 1 1 6292
binding 3.5377E-3 9 1294 6 6292

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