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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 480.10
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BBP1
  • spindle pole body
  • microtubule nucleation
  • spindle pole body duplication in nuclear envelope
  • structural constituent of cytoskeleton
  • CDC31
  • half bridge of spindle pole body
  • nuclear pore
  • microtubule nucleation
  • spindle pole body duplication in nuclear envelope
  • structural constituent of cytoskeleton
  • CMD1
  • incipient cellular bud site
  • cellular bud tip
  • central plaque of spindle pole body
  • cytoplasm
  • cellular bud neck
  • mating projection tip
  • cytoskeleton organization
  • cell budding
  • vacuole fusion, non-autophagic
  • mitosis
  • endocytosis
  • protein binding
  • calcium ion binding
  • calcium-dependent protein binding
  • CNM67
  • outer plaque of spindle pole body
  • spindle pole body
  • mitotic spindle organization
  • microtubule nucleation
  • structural constituent of cytoskeleton
  • KAR1
  • half bridge of spindle pole body
  • spindle pole body duplication in nuclear envelope
  • karyogamy involved in conjugation with cellular fusion
  • protein binding
  • NUD1
  • spindle pole body
  • microtubule nucleation
  • structural constituent of cytoskeleton
  • SPC105
  • mitochondrion
  • spindle pole body
  • microtubule nucleation
  • structural constituent of cytoskeleton
  • SPC110
  • inner plaque of spindle pole body
  • central plaque of spindle pole body
  • microtubule nucleation
  • structural constituent of cytoskeleton
  • SPC24
  • condensed nuclear chromosome, centromeric region
  • Ndc80 complex
  • condensed nuclear chromosome kinetochore
  • microtubule nucleation
  • chromosome segregation
  • structural constituent of cytoskeleton
  • SPC25
  • condensed nuclear chromosome, centromeric region
  • Ndc80 complex
  • condensed nuclear chromosome kinetochore
  • microtubule nucleation
  • chromosome segregation
  • structural constituent of cytoskeleton
  • SPC29
  • central plaque of spindle pole body
  • microtubule nucleation
  • spindle pole body duplication in nuclear envelope
  • structural constituent of cytoskeleton
  • SPC42
  • intermediate layer of spindle pole body
  • central plaque of spindle pole body
  • microtubule nucleation
  • spindle pole body duplication in nuclear envelope
  • structural constituent of cytoskeleton
  • SPC72
  • outer plaque of spindle pole body
  • mitotic spindle elongation
  • microtubule nucleation
  • mitotic sister chromatid segregation
  • nuclear migration along microtubule
  • structural constituent of cytoskeleton
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    microtubule organizing center 3.1131E-21 13 63 11 6292
    spindle pole body 3.1131E-21 13 63 11 6292
    spindle pole 7.7388E-21 13 68 11 6292
    spindle 1.8321E-19 13 89 11 6292
    microtubule organizing center part 2.7155E-19 13 16 8 6292
    microtubule cytoskeleton 1.3877E-18 13 106 11 6292
    cytoskeletal part 1.9906E-15 13 201 11 6292
    cytoskeleton 4.4607E-15 13 216 11 6292
    non-membrane-bounded organelle 2.2351E-11 13 959 13 6292
    intracellular non-membrane-bounded organelle 2.2351E-11 13 959 13 6292
    central plaque of spindle pole body 5.4733E-11 13 5 4 6292
    intracellular organelle part 1.8381E-6 13 2282 13 6292
    organelle part 1.8381E-6 13 2282 13 6292
    Ndc80 complex 2.3591E-5 13 4 2 6292
    half bridge of spindle pole body 3.9273E-5 13 5 2 6292
    outer plaque of spindle pole body 5.8841E-5 13 6 2 6292
    cytoplasmic part 1.1346E-3 13 2482 11 6292
    intermediate layer of spindle pole body 2.0661E-3 13 1 1 6292
    intracellular organelle 3.4477E-3 13 4070 13 6292
    organelle 3.4587E-3 13 4071 13 6292
    condensed nuclear chromosome kinetochore 4.3876E-3 13 49 2 6292
    condensed chromosome kinetochore 4.3876E-3 13 49 2 6292
    condensed chromosome, centromeric region 5.5019E-3 13 55 2 6292
    condensed nuclear chromosome, centromeric region 5.5019E-3 13 55 2 6292
    kinetochore 6.5197E-3 13 60 2 6292
    chromosome, centromeric region 8.078E-3 13 67 2 6292
    inner plaque of spindle pole body 8.2408E-3 13 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    microtubule nucleation 6.916E-27 13 23 11 6292
    microtubule cytoskeleton organization 1.1506E-21 13 97 12 6292
    microtubule-based process 6.352E-21 13 111 12 6292
    cytoskeleton organization 1.5803E-19 13 231 13 6292
    spindle pole body duplication in nuclear envelope 3.1104E-11 13 14 5 6292
    spindle pole body duplication 4.6607E-11 13 15 5 6292
    microtubule organizing center organization 9.5835E-11 13 17 5 6292
    spindle pole body organization 9.5835E-11 13 17 5 6292
    organelle organization 1.8449E-10 13 1127 13 6292
    cellular component organization 1.5465E-8 13 1582 13 6292
    cell cycle process 1.1607E-6 13 490 8 6292
    cell cycle 1.9706E-6 13 525 8 6292
    cellular component assembly 7.1393E-4 13 385 5 6292
    chromosome segregation 2.0259E-3 13 128 3 6292
    mitotic spindle organization 4.2134E-3 13 48 2 6292
    spindle organization 4.3876E-3 13 49 2 6292
    cellular component biogenesis 9.7186E-3 13 694 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of cytoskeleton 3.8648E-22 13 53 11 6292
    structural molecule activity 6.7238E-13 13 339 11 6292
    calcium-dependent protein binding 2.0661E-3 13 1 1 6292

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