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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 6 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC55
  • nucleus
  • cellular bud tip
  • cellular bud neck
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • negative regulation of exit from mitosis
  • protein amino acid dephosphorylation
  • pseudohyphal growth
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • PPH21
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • PPH22
  • condensed nuclear chromosome, centromeric region
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • TPD3
  • nucleus
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • mating projection tip
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • ZDS1
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • nuclear pore
  • mRNA export from nucleus
  • chromatin silencing
  • cell aging
  • protein binding
  • ZDS2
  • nucleus
  • chromatin silencing at rDNA
  • cell aging
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 2A complex 3.4469E-12 6 6 4 6292
    protein serine/threonine phosphatase complex 5.4538E-10 6 17 4 6292
    cellular bud tip 1.3832E-5 6 57 3 6292
    cellular bud neck 1.6098E-4 6 129 3 6292
    cellular bud 3.4022E-4 6 166 3 6292
    site of polarized growth 3.5249E-4 6 168 3 6292
    protein complex 9.756E-4 6 1137 5 6292
    macromolecular complex 5.5477E-3 6 1635 5 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mitotic cell cycle spindle assembly checkpoint 1.3701E-9 6 21 4 6292
    negative regulation of nuclear division 1.3701E-9 6 21 4 6292
    negative regulation of mitosis 1.3701E-9 6 21 4 6292
    negative regulation of mitotic metaphase/anaphase transition 1.3701E-9 6 21 4 6292
    spindle assembly checkpoint 1.3701E-9 6 21 4 6292
    negative regulation of cell cycle 1.6741E-9 6 22 4 6292
    spindle checkpoint 2.8929E-9 6 25 4 6292
    regulation of mitotic metaphase/anaphase transition 2.8929E-9 6 25 4 6292
    mitotic cell cycle spindle checkpoint 2.8929E-9 6 25 4 6292
    negative regulation of cellular process 3.7127E-9 6 250 6 6292
    negative regulation of biological process 3.9911E-9 6 253 6 6292
    mitotic cell cycle checkpoint 4.6787E-9 6 28 4 6292
    protein amino acid dephosphorylation 4.6787E-9 6 28 4 6292
    negative regulation of cellular component organization 5.426E-9 6 29 4 6292
    regulation of nuclear division 5.426E-9 6 29 4 6292
    negative regulation of organelle organization 5.426E-9 6 29 4 6292
    regulation of mitosis 5.426E-9 6 29 4 6292
    negative regulation of cell cycle process 8.2088E-9 6 32 4 6292
    budding cell bud growth 1.0581E-8 6 34 4 6292
    mitotic metaphase/anaphase transition 1.5057E-8 6 37 4 6292
    dephosphorylation 2.082E-8 6 40 4 6292
    regulation of organelle organization 6.1485E-8 6 52 4 6292
    cell cycle checkpoint 9.6209E-8 6 58 4 6292
    actin filament organization 1.842E-7 6 68 4 6292
    regulation of mitotic cell cycle 2.196E-7 6 71 4 6292
    regulation of cellular component organization 2.7442E-7 6 75 4 6292
    regulation of cell cycle process 3.7506E-7 6 81 4 6292
    cell budding 5.7469E-7 6 90 4 6292
    asexual reproduction 5.7469E-7 6 90 4 6292
    mitosis 1.0304E-6 6 104 4 6292
    nuclear division 1.1127E-6 6 106 4 6292
    organelle fission 1.4396E-6 6 113 4 6292
    actin cytoskeleton organization 1.4396E-6 6 113 4 6292
    actin filament-based process 1.6559E-6 6 117 4 6292
    M phase of mitotic cell cycle 2.3759E-6 6 128 4 6292
    regulation of cell cycle 2.6075E-6 6 131 4 6292
    growth 3.9173E-6 6 145 4 6292
    cell division 3.9173E-6 6 145 4 6292
    regulation of cellular process 4.0325E-6 6 796 6 6292
    regulation of biological process 4.9653E-6 6 824 6 6292
    signal transduction 1.8503E-5 6 214 4 6292
    signal transmission 1.9555E-5 6 217 4 6292
    signaling process 1.9555E-5 6 217 4 6292
    reproduction of a single-celled organism 1.9555E-5 6 217 4 6292
    phosphorus metabolic process 2.4213E-5 6 229 4 6292
    phosphate metabolic process 2.4213E-5 6 229 4 6292
    cytoskeleton organization 2.5062E-5 6 231 4 6292
    signaling 3.5378E-5 6 252 4 6292
    mitotic cell cycle 3.7074E-5 6 255 4 6292
    cellular macromolecule biosynthetic process 4.4618E-5 6 1187 6 6292
    macromolecule biosynthetic process 4.5072E-5 6 1189 6 6292
    biological regulation 5.0826E-5 6 1213 6 6292
    M phase 6.5045E-5 6 294 4 6292
    gene expression 7.1216E-5 6 1283 6 6292
    reproduction 1.0008E-4 6 328 4 6292
    post-translational protein modification 1.3958E-4 6 357 4 6292
    cell cycle phase 1.7103E-4 6 376 4 6292
    translation 1.7103E-4 6 376 4 6292
    cellular biosynthetic process 2.3689E-4 6 1567 6 6292
    biosynthetic process 2.7052E-4 6 1602 6 6292
    cell cycle process 4.8022E-4 6 490 4 6292
    protein modification process 5.1534E-4 6 499 4 6292
    cell cycle 6.2738E-4 6 525 4 6292
    macromolecule modification 8.5609E-4 6 569 4 6292
    cell aging 8.7368E-4 6 49 2 6292
    G1/S transition of mitotic cell cycle 9.0969E-4 6 50 2 6292
    aging 9.4642E-4 6 51 2 6292
    cellular macromolecule metabolic process 2.2844E-3 6 2285 6 6292
    macromolecule metabolic process 2.6967E-3 6 2349 6 6292
    interphase of mitotic cell cycle 3.389E-3 6 97 2 6292
    interphase 3.389E-3 6 97 2 6292
    negative regulation of gene expression, epigenetic 3.5984E-3 6 100 2 6292
    gene silencing 3.5984E-3 6 100 2 6292
    regulation of gene expression, epigenetic 3.5984E-3 6 100 2 6292
    chromatin silencing 3.5984E-3 6 100 2 6292
    negative regulation of exit from mitosis 3.8098E-3 6 4 1 6292
    negative regulation of transcription, DNA-dependent 8.688E-3 6 157 2 6292
    negative regulation of RNA metabolic process 8.7956E-3 6 158 2 6292
    negative regulation of transcription 9.4541E-3 6 164 2 6292
    negative regulation of gene expression 9.4541E-3 6 164 2 6292
    cellular protein metabolic process 9.4683E-3 6 1074 4 6292
    primary metabolic process 9.4808E-3 6 2896 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein serine/threonine phosphatase activity 1.2428E-6 6 26 3 6292
    phosphoprotein phosphatase activity 5.8633E-6 6 43 3 6292
    phosphatase activity 4.9568E-5 6 87 3 6292
    phosphoric ester hydrolase activity 7.986E-5 6 102 3 6292
    metal ion binding 1.1004E-3 6 55 2 6292
    ion binding 1.1407E-3 6 56 2 6292
    cation binding 1.1407E-3 6 56 2 6292
    hydrolase activity, acting on ester bonds 2.7916E-3 6 341 3 6292
    protein phosphatase type 2A regulator activity 3.8098E-3 6 4 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle