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Protein Overview: HUB1

General Information:
Name(s) found: HUB1 / YNR032C-A [SGD]
Description(s) found:
Found 24 descriptions.
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  • Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 73 amino acids

    Gene Ontology:
    Cellular Component: mating projection [IPILink to PubMed article]
    Biological Process: protein modification process [IDALink to PubMed article]
    cell morphogenesis involved in conjugation with cellular fusion [IMPLink to PubMed article]
    nuclear mRNA splicing, via spliceosome [IPILink to PubMed article][ISSLink to PubMed article]
    Molecular Function: protein tag [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIEVVVNDRL GKKVRVKCLA EDSVGDFKKV LSLQIGTQPN KIVLQKGGSV LKDHISLEDY  60
   61 EVHDQTNLEL YYL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen HUB1 SNU66 2 Unpublished Fields Lab Data
    View Screen HUB1 SNU66 2 Unpublished Fields Lab Data
    View Screen HUB1 SNU66 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] PSI-BLAST 2.045757 Ubiquitin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  3.47895265760328 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  2.99122127270119 bayes_pls_golite062009
  • binding
    		•  2.5881743465274 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.56275248067993 bayes_pls_golite062009
  • protein tag
    		•  2.15059229834935 bayes_pls_golite062009
  • protein binding
    		•  1.76858817153382 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  1.25223828115784 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.11533445164506 bayes_pls_golite062009
  • RNA binding
    		•  1.00651240292915 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.896431097217265 bayes_pls_golite062009
  • DNA binding
    		•  0.859811565165317 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.80391127659342 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.536856055841234 bayes_pls_golite062009
  • kinase activity
    		•  0.506057697290914 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.410719674374641 bayes_pls_golite062009
  • protein kinase activity
    		•  0.325253662829604 bayes_pls_golite062009
  • transferase activity
    		•  0.236208643697075 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle