YRC Public Data Repository - Protein Structure Prediction

Protein:	HUB1
Organism:	Saccharomyces cerevisiae
Length:	73 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HUB1.

Description	E-value	Query Range	Subject Range
gi\|109123317, gi... - gi\|109123319\|ref\|XP_001098907.1\| PREDICTED: similar to ubiquitin-like 5 isoform 2 [Macaca mulatta], ... gi\|149020555, gi... - gi\|163916622\|gb\|AAI57819.1\| Ubiquitin-like 5 [Rattus norvegicus], gi\|149020555\|gb\|EDL78360.1\| Ubiqui... tr\|M3WBB7\|M3WBB7... - Uncharacterized protein OS=Felis catus GN=UBL5 PE=4 SV=1 ENSOCUP000000261... - pep:novel scaffold:oryCun2:GL018833:401410:402367:-1 gene:ENSOCUG00000029004 transcript:ENSOCUT00000... UBL5_MOUSE - Ubiquitin-like protein 5 OS=Mus musculus GN=Ubl5 PE=1 SV=1 gi\|61361418, gi\|... - gi\|61361418\|gb\|AAX42045.1\| ubiquitin-like 5 [synthetic construct], gi\|61361411\|gb\|AAX42044.1\| ubiqui... gi\|55727544 - gi\|55727544\|emb\|CAH90527.1\| hypothetical protein [Pongo abelii] CCDS12219.1_1 - null gi\|149755469 - gi\|149755469\|ref\|XP_001493726.1\| PREDICTED: similar to ubiquitin-like 5 [Equus caballus] ENSCJAT00000011834 - null gi\|73987008 - gi\|73987008\|ref\|XP_854056.1\| PREDICTED: similar to ubiquitin-like 5 [Canis familiaris] UBL5_MESAU - Ubiquitin-like protein 5 OS=Mesocricetus auratus GN=UBL5 PE=3 SV=1 UBL5_PSAOB - Ubiquitin-like protein 5 OS=Psammomys obesus GN=UBL5 PE=3 SV=1 UBL5_BOVIN - Ubiquitin-like protein 5 OS=Bos taurus GN=UBL5 PE=3 SV=1 gi\|67970579, gi\|... - gi\|67970579\|dbj\|BAE01632.1\| unnamed protein product [Macaca fascicularis], gi\|67969364\|dbj\|BAE01034.... gi\|114675265 - gi\|114675265\|ref\|XP_512356.2\| PREDICTED: similar to beacon [Pan troglodytes] UBL5 - ubiquitin-like 5 gi\|126322901 - gi\|126322901\|ref\|XP_001363867.1\| PREDICTED: similar to beacon [Monodelphis domestica] gi\|197102826 - gi\|197102826\|ref\|NP_001125281.1\| ubiquitin-like 5 [Pongo abelii] gi\|195182331 - gi\|195182331\|emb\|CAQ34910.1\| ubiquitin-like protein 5 [Sus scrofa]	6.0E-32	[1..72]	[1..72]
hub1 - ubiquitin-like protein modifier Hub1 HUB1_SCHPO - Ubiquitin-like modifier hub1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=hub1 PE=1 SV=...	2.0E-31	[1..72]	[1..72]
ubl-5 - status:Confirmed UniProt:P91302 protein_id:AAK21382.1 gi\|157745431 - gi\|157745431\|ref\|XP_001667812.1\| Hypothetical protein CBG14905 [Caenorhabditis briggsae AF16] gi\|39598234, gi\|... - gi\|39598234\|emb\|CAE68926.1\| Hypothetical protein CBG14905 [Caenorhabditis briggsae], gi\|187027540\|em... CRE03637 - RP07575 WBGene00060372 locus:Cre-ubl-5 status:Predicted	3.0E-31	[1..72]	[1..72]
gi\|220951280 - gi\|220951280\|gb\|ACL88183.1\| ubl-PA [synthetic construct] gi\|195331931, gi... - gi\|195331931\|ref\|XP_002032652.1\| GM20845 [Drosophila sechellia], gi\|194124622\|gb\|EDW46665.1\| GM20845... gi\|195581030, gi... - gi\|195581030\|ref\|XP_002080337.1\| GD10297 [Drosophila simulans], gi\|194192346\|gb\|EDX05922.1\| GD10297 ... ubl-PA - The gene ubiquitin like is referred to in FlyBase by the symbol Dmel\ubl (CG3450, FBgn0022224). It i...	5.0E-31	[1..72]	[1..72]
gi\|15230632, gi\|... - gi\|6911856\|emb\|CAB72156.1\| putative protein [Arabidopsis thaliana], gi\|15230632\|ref\|NP_190104.1\| ubi...	1.0E-29	[1..72]	[1..72]
gi\|151944560 - gi\|151944560\|gb\|EDN62838.1\| conserved protein [Saccharomyces cerevisiae YJM789] gi\|190408970 - gi\|190408970\|gb\|EDV12235.1\| hypothetical protein SCRG_03110 [Saccharomyces cerevisiae RM11-1a] HUB1_YEAST - Ubiquitin-like modifier HUB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HUB1 PE=1 S... HUB1 - Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally compl...	1.0E-27	[1..73]	[1..73]
gi\|85082085 - gi\|85082085\|ref\|XP_956844.1\| hypothetical protein [Neurospora crassa OR74A] gi\|18376369, gi\|... - gi\|32404084\|ref\|XP_322655.1\| hypothetical protein [Neurospora crassa], gi\|28917923\|gb\|EAA27608.1\| hy...	9.0E-24	[1..70]	[185..255]

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Predicted Domain #1

Region A:
Residues: [1-73]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIEVVVNDRL GKKVRVKCLA EDSVGDFKKV LSLQIGTQPN KIVLQKGGSV LKDHISLEDY  60
   61 EVHDQTNLEL YYL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2.045757
Match:	1ud7A_
Description:	Ubiquitin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
small conjugating protein ligase activity	3.47895265760328	bayes_pls_golite062009
ubiquitin-protein ligase activity	2.99122127270119	bayes_pls_golite062009
binding	2.5881743465274	bayes_pls_golite062009
acid-amino acid ligase activity	2.56275248067993	bayes_pls_golite062009
protein tag	2.15059229834935	bayes_pls_golite062009
protein binding	1.76858817153382	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	1.25223828115784	bayes_pls_golite062009
transcription regulator activity	1.11533445164506	bayes_pls_golite062009
RNA binding	1.00651240292915	bayes_pls_golite062009
nucleic acid binding	0.896431097217265	bayes_pls_golite062009
DNA binding	0.859811565165317	bayes_pls_golite062009
SUMO ligase activity	0.80391127659342	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.536856055841234	bayes_pls_golite062009
kinase activity	0.506057697290914	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.410719674374641	bayes_pls_golite062009
protein kinase activity	0.325253662829604	bayes_pls_golite062009
transferase activity	0.236208643697075	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: