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Protein Overview: SDS24

General Information:
Name(s) found: SDS24 / YBR214W [SGD]
Description(s) found:
Found 28 descriptions.
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  • One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; involved in cell separation during budding; may play an indirect role in fluid-phase endocytosis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 527 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: DNA metabolic process [IGILink to PubMed article]
    endocytosis [IMPLink to PubMed article]
    meiosis [IEPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTSNTFPP SQSNSSNNLP TSRHASIVEM LSTPPLLPHV QVNDTDDKEQ PEESTPPTAT  60
   61 AAAPGPGCAA TPAPLRDEKP QFKLSAVPMT QTPSQCLSCV HAQKWQHIPL SQLIEQNKLI 120
  121 FVPGSISVEE AFNTLIKYHL NSIPVESFPG DMNCFTFDYN DLNSYLLLVL NKITVSNKQL 180
  181 TADCQNGKPV PVGEMVKLTP KNPFYKLPEN ESLSTVMGIL GSGVHRVAIT NEEMTKVKGI 240
  241 LSQRRLIKYL WDNARSFTSL EPLLNSSLQD LHIGVLNIQS KPTSRQSRVI SIQGEEPLIM 300
  301 GLYKMHVERI SSIAVIDKQG NLLGNISVTD VKHVTRTSQY PLLHKTCRHF ISVILNSRGL 360
  361 ETGKDSFPIF HVYPSSSLAR TLAKLVATKS HRLWIVQPPE SSTSASSTNL TAANTAANAV 420
  421 SATAQSSANG ATPMSKSSSS TSLNSHSPLM TAMEDPPSPR SSAIAIPPPS PASSTNTPNL 480
  481 FEKEYRTGKL IGVVSLTDII NLLARKQTGN KEVDPQSARR QRGSIAM

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HRT3 PPZ2 SAP155 SDS24 SIT4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SDS24 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] deduced N/A No confident structure predictions are available.
    2 View Details [96..197]
    [333..527]    		 PSI-BLAST 35.045757 Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase
    3 View Details [198..332] PSI-BLAST 35.045757 Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transporter activity
    		•  0.961062314616209 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.807029018941177 bayes_pls_golite062009
  • binding
    		•  0.804248460382476 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.640881170978843 bayes_pls_golite062009
  • protein binding
    		•  0.5290109527055 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.525366315833255 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.440262824681055 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle