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Protein Overview: PWP2

General Information:
Name(s) found: PWP2 [HGNC (HUGO)]
Description(s) found:
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  • gi|7768771|dbj|BAA95553.1| periodic tryptophan protein 2 homolog [Homo sapiens] [NCBI NR]
  • gi|48762926|ref|NP_005040.2| PWP2 periodic tryptophan protein homolog [Homo sapiens] [NCBI NR]
  • gi|2250699|dbj|BAA21137.1| PWP2 protein [Homo sapiens] [NCBI NR]
  • gi|116242740|sp|Q15269.2|PWP2_HUMAN RecName: Full=Periodic tryptophan protein 2 homolog [NCBI NR]
  • PWP2 periodic tryptophan protein homolog (yeast) [HGNC (HUGO)]
  • Periodic tryptophan protein 2 homolog OS=Homo sapiens GN=PWP2 PE=2 SV=2 [Swiss-Prot]
  • periodic tryptophan protein 2 homolog; PWP2 (periodic tryptophan protein, yeast) homolog [071204_hmrz_cont.fasta]
  • periodic tryptophan protein 2 homolog; PWP2 (periodic tryptophan protein, yeast) homolog [Homo sapiens]gi|2250699|dbj|BAA21137.1| PWP2 protein [Homo sapiens]gi|7768771|dbj|BAA95553.1| periodic tryptophan protein 2 homolog [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • PWP2 periodic tryptophan protein homolog [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • periodic tryptophan protein 2 homolog [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Periodic tryptophan protein 2 homolog [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • PWP2 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Periodic tryptophan protein 2 homolog [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PWP2 Periodic tryptophan protein 2 homolog [human-ipi-250309-contam.fasta]
  • IPI:IPI00300078.6|SWISS-PROT:Q15269|TREMBL:B2RAG8|ENSEMBL:ENSP00000291576|REFSEQ:NP_005040|H-INV:HIT000324898|VEGA:OTTHUMP00000109488 Tax_Id=9606 Gene_Symbol=PWP2 Periodic tryptophan protein 2 homolog [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PWP2 Periodic tryptophan protein 2 homolog ENSG00000160220 IPI00300078 IPI00797937 [drosphohumanreversed.fasta]
  • Periodic tryptophan protein 2 homolog OS=Homo sapiens GN=PWP2 PE=1 SV=2 [UniProtHuman070710.fasta]
  • Q15269;B2RAG8;Q96A77; RecName: Full=Periodic tryptophan protein 2 homolog; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Periodic tryptophan protein 2 homolog OS=Homo sapiens GN=PWP2 [011711_HMR.fasta]
  • IPI:IPI00300078.6|SWISS-PROT:Q15269|ENSEMBL:ENSP00000291576|REFSEQ:NP_005040|H-INV:HIT000324898|VEGA:OTTHUMP00000109488 Tax_Id=9606 Gene_Symbol=PWP2 Periodic tryptophan protein 2 homolog [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=PWP2 Synonyms=EHOC-17|PWP2H periodic tryptophan protein 2 homolog [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00300078.6|SWISS-PROT:Q15269|ENSEMBL:ENSP00000291576|REFSEQ:NP_005040|VEGA:OTTHUMP00000109488 Tax_Id=9606 Gene_Symbol=PWP2 Periodic tryptophan protein 2 homolog [ipi.HUMAN.20110912.fasta]
  • Periodic tryptophan protein 2 homolog GN=PWP2 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 919 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFAYRFSNL LGTVYRRGNL NFTCDGNSVI SPVGNRVTVF DLKNNKSDTL PLATRYNVKC  60
   61 VGLSPDGRLA IIVDEGGDAL LVSLVCRSVL HHFHFKGSVH SVSFSPDGRK FVVTKGNIAQ 120
  121 MYHAPGKKRE FNAFVLDKTY FGPYDETTCI DWTDDSRCFV VGSKDMSTWV FGAERWDNLI 180
  181 YYALGGHKDA IVACFFESNS LDLYSLSQDG VLCMWQCDTP PEGLRLKPPA GWKADLLQRE 240
  241 EEEEEEEDQE GDRETTIRGK ATPAEEEKTG KVKYSRLAKY FFNKEGDFNN LTAAAFHKKS 300
  301 HLLVTGFASG IFHLHELPEF NLIHSLSISD QSIASVAINS SGDWIAFGCS GLGQLLVWEW 360
  361 QSESYVLKQQ GHFNSMVALA YSPDGQYIVT GGDDGKVKVW NTLSGFCFVT FTEHSSGVTG 420
  421 VTFTATGYVV VTSSMDGTVR AFDLHRYRNF RTFTSPRPTQ FSCVAVDASG EIVSAGAQDS 480
  481 FEIFVWSMQT GRLLDVLSGH EGPISGLCFN PMKSVLASAS WDKTVRLWDM FDSWRTKETL 540
  541 ALTSDALAVT FRPDGAELAV ATLNSQITFW DPENAVQTGS IEGRHDLKTG RKELDKITAK 600
  601 HAAKGKAFTA LCYSADGHSI LAGGMSKFVC IYHVREQILM KRFEISCNLS LDAMEEFLNR 660
  661 RKMTEFGNLA LIDQDAGQED GVAIPLPGVR KGDMSSRHFK PEIRVTSLRF SPTGRCWAAT 720
  721 TTEGLLIYSL DTRVLFDPFE LDTSVTPGRV REALRQQDFT RAILMALRLN ESKLVQEALE 780
  781 AVPRGEIEVV TSSLPELYVE KVLEFLASSF EVSRHLEFYL LWTHKLLMLH GQKLKSRAGT 840
  841 LLPVIQFLQK SIQRHLDDLS KLCSWNHYNM QYALAVSKQR GTKRSLDPLG SEEEAEASED 900
  901 DSLHLLGGGG RDSEEEMLA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..319] PSI-BLAST 44.0 PAF-AH Holoenzyme: Lis1/Alfa2
    2 View Details [320..455] FFAS03 5.54 No description for 2gnqA was found.
    3 View Details [456..522] PSI-BLAST 48.522879 No description for 2gnqA was found.
    4 View Details [523..812] PSI-BLAST 5.39794 No description for 2oitA was found.
    5 View Details [813..919] Pfam 21.920819 No description for PF04047.5 was found. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
    		• 6.67009948605948 bayes_pls_golite062009
  • snoRNA binding
    		•  6.03079504484743 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
    		•  4.71992275913384 bayes_pls_golite062009
  • actin binding
    		•  3.86142918698875 bayes_pls_golite062009
  • RNA binding
    		•  3.77273677738815 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.25521258308263 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • dynein binding
    		•  2.54821997913979 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • actin filament binding
    		•  2.0735069176589 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.85632145559025 bayes_pls_golite062009
  • dynactin binding
    		•  1.85146647785657 bayes_pls_golite062009
  • transporter activity
    		•  1.65168247201205 bayes_pls_golite062009
  • structural molecule activity
    		•  1.47097979074281 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.42548927439572 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  1.35170368882651 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.22384651674093 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.20712373307552 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • mRNA binding
    		•  1.05053985350578 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.01166033978052 bayes_pls_golite062009
  • myosin binding
    		•  0.989691178611801 bayes_pls_golite062009
  • DNA binding
    		•  0.963493426709289 bayes_pls_golite062009
  • kinase activity
    		•  0.807669232329985 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.805273887494167 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.634547834947756 bayes_pls_golite062009
  • protein kinase activity
    		•  0.544118712921054 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.443846546939402 bayes_pls_golite062009
  • transcription factor activity
    		•  0.435575551078191 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.367729389382533 bayes_pls_golite062009
  • signal transducer activity
    		•  0.367729389382533 bayes_pls_golite062009
  • myosin II binding
    		•  0.33142771724387 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.298055197418849 bayes_pls_golite062009
  • ligase activity
    		•  0.20682813699621 bayes_pls_golite062009
  • transcription factor binding
    		•  0.136928257321035 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.121183207943714 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.0803897416817422 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.00335766408304172 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle