Protein Overview: APOA1_RAT

General Information:
Name(s) found:	APOA1_RAT [Swiss-Prot]
Description(s) found: Found 20 descriptions. SHOW ALL	Apolipoprotein A-I OS=Rattus norvegicus GN=Apoa1 PE=1 SV=2 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	259 amino acids
Gene Ontology:
Cellular Component:	very-low-density lipoprotein particle [UNKNOWN] nucleus [IDA] endoplasmic reticulum lumen [UNKNOWN] endocytic vesicle [UNKNOWN] extracellular space [UNKNOWN][IDA] high-density lipoprotein particle [UNKNOWN][IEA] secretory granule [UNKNOWN] cytoplasmic vesicle [UNKNOWN] spherical high-density lipoprotein particle [UNKNOWN] extracellular region [UNKNOWN][IEA] plasma membrane [UNKNOWN]
Biological Process:	cholesterol import [UNKNOWN] lipid storage [UNKNOWN] response to estrogen stimulus [IEP] [NOT]protein localization [UNKNOWN] cholesterol metabolic process [UNKNOWN][IEA] steroid metabolic process [IEA] lipoprotein metabolic process [IEA] phospholipid metabolic process [UNKNOWN] lipoprotein biosynthetic process [UNKNOWN] cholesterol homeostasis [UNKNOWN] negative regulation of cytokine secretion during immune response [UNKNOWN] positive regulation of hydrolase activity [UNKNOWN] negative regulation of hydrolase activity [UNKNOWN] reverse cholesterol transport [UNKNOWN] Cdc42 protein signal transduction [UNKNOWN] negative regulation of interleukin-1 beta secretion [UNKNOWN] cholesterol transport [UNKNOWN][IDA] regulation of intestinal cholesterol absorption [UNKNOWN] positive regulation of cholesterol esterification [UNKNOWN] adrenal gland development [UNKNOWN] positive regulation of transferase activity [UNKNOWN] axon regeneration in the peripheral nervous system [IEP] high-density lipoprotein particle assembly [UNKNOWN] G-protein coupled receptor protein signaling pathway [UNKNOWN] cholesterol biosynthetic process [UNKNOWN] response to nutrient [IEP] glucocorticoid metabolic process [UNKNOWN] blood vessel endothelial cell migration [UNKNOWN] phosphatidylcholine biosynthetic process [UNKNOWN] negative regulation of catalytic activity [IDA] regulation of protein amino acid phosphorylation [UNKNOWN] negative regulation of very-low-density lipoprotein particle remodeling [UNKNOWN] response to drug [IEP] endothelial cell proliferation [UNKNOWN] phospholipid transport [IDA] cholesterol efflux [UNKNOWN] organ regeneration [IDA] protein stabilization [UNKNOWN] [NOT]axon regeneration [UNKNOWN] phospholipid efflux [UNKNOWN]
Molecular Function:	identical protein binding [UNKNOWN] lipoprotein binding [UNKNOWN] cholesterol binding [UNKNOWN] phosphatidylcholine-sterol O-acyltransferase activator activity [UNKNOWN] lipid binding [UNKNOWN][IEA] high-density lipoprotein binding [UNKNOWN] phospholipid binding [UNKNOWN] apolipoprotein A-I receptor binding [UNKNOWN] beta-amyloid binding [UNKNOWN] apolipoprotein receptor binding [UNKNOWN] protein binding [UNKNOWN] phospholipid transporter activity [IDA] enzyme inhibitor activity [IDA] lipid transporter activity [UNKNOWN] high-density lipoprotein receptor binding [UNKNOWN] cholesterol transporter activity [UNKNOWN][IDA] enzyme binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAAVLAVAL VFLTGCQAWE FWQQDEPQSQ WDRVKDFATV YVDAVKDSGR DYVSQFESST  60
   61 LGKQLNLNLL DNWDTLGSTV GRLQEQLGPV TQEFWANLEK ETDWLRNEMN KDLENVKQKM 120
  121 QPHLDEFQEK WNEEVEAYRQ KLEPLGTELH KNAKEMQRHL KVVAEEFRDR MRVNADALRA 180
  181 KFGLYSDQMR ENLAQRLTEI KNHPTLIEYH TKASDHLKTL GEKAKPALDD LGQGLMPVLE 240
  241 AWKAKIMSMI DEAKKKLNA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: APOA1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: