Protein Overview: HDAC1_RAT

General Information:
Name(s) found:	HDAC1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81918177\|sp\|Q4QQW4.1\|HDAC1_RAT RecName: Full=Histone deacetylase 1; Short=HD1 [NCBI NR] gi\|78174349\|gb\|AAI07477.1\| Histone deacetylase 1 [Rattus norvegicus] [NCBI NR] gi\|70794768\|ref\|NP_001020580.1\| histone deacetylase 1 [Rattus norvegicus] [NCBI NR] gi\|67678279\|gb\|AAH97943.1\| Histone deacetylase 1 [Rattus norvegicus] [NCBI NR] ref\|XP_216349.2\| similar to histone deacetylase [Rattus norvegicus] [NCBI NR] gi\|149024048\|gb\|EDL80545.1\| rCG31110 [Rattus norvegicus] [NCBI NR] Histone deacetylase 1 OS=Rattus norvegicus GN=Hdac1 PE=1 SV=1 [Swiss-Prot] similar to histone deacetylase [HMR_022704-rand.fasta] similar to histone deacetylase [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Histone deacetylase 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Hypothetical protein [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Tax_Id=10116 Similar to hiStone deacetylaSe [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Histone deacetylase 1 (HD1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] histone deacetylase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG31110 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Histone deacetylase 1 (predicted) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SIMILAR TO HISTONE DEACETYLASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Hdac1;Hdac1l Histone deacetylase 1 [rat-ipi-250309-contam.fasta] Histone deacetylase 1 OS=Rattus norvegicus GN=Hdac1 [011711_HMR.fasta] Histone deacetylase 1 OS=Rattus norvegicus GN=Hdac1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	482 amino acids
Gene Ontology:
Cellular Component:	heterochromatin [UNKNOWN] nucleus [UNKNOWN][IDA] Sin3 complex [UNKNOWN] NuRD complex [UNKNOWN] histone deacetylase complex [UNKNOWN] cytosol [UNKNOWN] neuronal cell body [UNKNOWN] protein complex [IDA] chromatin [IDA] cellular_component [ND] nucleoplasm [UNKNOWN]
Biological Process:	chromatin modification [IEA] negative regulation by host of viral transcription [UNKNOWN] biological_process [ND] neuron differentiation [UNKNOWN] endoderm development [UNKNOWN] negative regulation of cell proliferation [IDA] positive regulation of cell proliferation [UNKNOWN] negative regulation of cell cycle [UNKNOWN] protein amino acid deacetylation [UNKNOWN] hippocampus development [UNKNOWN] negative regulation of neuron apoptosis [IMP] negative regulation of transcription [IDA] response to drug [IEP] cellular response to oxidative stress [IDA] [NOT]negative regulation of myotube differentiation [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] histone deacetylation [UNKNOWN] positive regulation of receptor biosynthetic process [UNKNOWN] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] histone H3 deacetylation [IMP]
Molecular Function:	identical protein binding [UNKNOWN] histone deacetylase binding [UNKNOWN] chromatin binding [UNKNOWN] transcription factor binding [UNKNOWN] molecular_function [ND] DNA binding [UNKNOWN] transcription factor activity [UNKNOWN] protein binding [UNKNOWN][IPI] histone deacetylase activity [UNKNOWN][IMP] transcription corepressor activity [UNKNOWN] transcription activator activity [UNKNOWN] transcription repressor activity [UNKNOWN][IDA] protein complex binding [IDA] protein deacetylase activity [UNKNOWN] specific transcriptional repressor activity [UNKNOWN] enzyme binding [UNKNOWN] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQTQGTKRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK MEIYRPHKAN  60
   61 AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRFNVGEDC PVFDGLFEFC QLSTGGSVAS 120
  121 AVKLNKQQTD IAVNWAGGLH HAKKSEASGF CYVNDIVLAI LELLKYHQRV LYIDIDIHHG 180
  181 DGVEEAFYTT DRVMTVSFHK YGEYFPGTGD LRDIGAGKGK YYAVNYPLRD GIDDESYEAI 240
  241 FKPVMSKVME MFQPSAVVLQ CGSDSLSGDR LGCFNLTIKG HAKCVEFVKS FNLPMLMLGG 300
  301 GGYTIRNVAR CWTYETAVAL DTEIPNELPY NDYFEYFGPD FKLHISPSNM TNQNTNEYLE 360
  361 KIKQRLFENL RMLPHAPGVQ MQAIPEDAIP EESGDEDEED PDKRISICSS DKRIACEEEF 420
  421 SDSDEEGEGG RKNSSNFKKA KRVKTEDEKE KDPEEKKEVT EEEKTKEEKP EAKGVKEEVK 480
  481 MA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HDAC1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: