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Protein Overview: TXNIP_RAT

General Information:
Name(s) found: TXNIP_RAT [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Thioredoxin-interacting protein OS=Rattus norvegicus GN=Txnip PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 394 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    mitochondrial intermembrane space [IDA]
    cytoplasm [UNKNOWN][IDA]
    Biological Process: response to progesterone stimulus [IEP]
    platelet-derived growth factor receptor signaling pathway [UNKNOWN][IEA]
    response to hydrogen peroxide [IEP]
    regulation of transcription [IEA]
    cell cycle [IEA]
    regulation of cell proliferation [IDA]
    response to mechanical stimulus [IEP]
    negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    response to oxidative stress [UNKNOWN][IEA]
    keratinocyte differentiation [UNKNOWN][IEA]
    response to glucose stimulus [IEP]
    protein import into nucleus [UNKNOWN][IEA]
    response to drug [IEP]
    response to calcium ion [IEP]
    positive regulation of apoptosis [IMP]
    response to estradiol stimulus [IEP]
    Molecular Function: protein binding [UNKNOWN][IEA]
    enzyme inhibitor activity [UNKNOWN][IEA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMFKKIKSF EVVFNDPEKV YGSGEKVAGR VTVEVCEVTR VKAVRILACG VAKVLWMQGS  60
   61 QQCKQTLDYL RYEDTLLLED QPTGENEMVI MRPGNKYEYK FGFELPQGPL GTSFKGKYGC 120
  121 VDYWVKAFLD RPSQPTQEAK KNFEVMDLVD VNTPDLMAPV SAKKEKKVSC MFIPDGRVSV 180
  181 SARIDRKGFC EGDDISIHAD FENTCSRIVV PKAAIVARHT YLANGQTKVL TQKLSSVRGN 240
  241 HIISGTCASW RGKSLRVQKI RPSILGCNIL RVEYSLLIYV SVPGSKKVIL DLPLVIGSRS 300
  301 GLSSRTSSMA SRTSSEMSWI DLNIPDTPEA PPCYMDVIPE DHRLESPTTP LLDDVDDSQD 360
  361 SPIFMYAPEF QFMPPPTYTE VDPCVLNNNN NNVQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle