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Protein Overview: PSB5_MOUSE

General Information:
Name(s) found: PSB5_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|77415527|gb|AAI06145.1| Proteasome (prosome, macropain) subunit, beta type 5 [Mus musculus] [NCBI NR]
  • gi|74228773|dbj|BAE21876.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|6755204|ref|NP_035316.1| proteasome (prosome, macropain) subunit, beta type 5 [Mus musculus] [NCBI NR]
  • gi|5757659|gb|AAD50536.1|AF060091_1 proteasome subunit X [Mus musculus] [NCBI NR]
  • gi|2897809|dbj|BAA24917.1| PSMB5 [Mus musculus] [NCBI NR]
  • gi|2897806|dbj|BAA24916.1| PSMB5 [Mus musculus] [NCBI NR]
  • gi|187608891|sp|O55234.3|PSB5_MOUSE RecName: Full=Proteasome subunit beta type-5; AltName: Full=Proteasome epsilon chain; AltName: Full=Macropain epsilon chain; AltName: Full=Multicatalytic endopeptidase complex epsilon chain; AltName: Full=Proteasome sub [NCBI NR]
  • gi|148704392|gb|EDL36339.1| mCG8712, isoform CRA_b [Mus musculus] [NCBI NR]
  • Proteasome subunit beta type-5 OS=Mus musculus GN=Psmb5 PE=1 SV=3 [Swiss-Prot]
  • proteasome (prosome, macropain) subunit, beta type 5; proteasome beta type subunit 5 [HMR_022704-rand.fasta]
  • proteasome (prosome, macropain) subunit, beta type 5 [Mus musculus]gi|5757659|gb|AAD50536.1| proteasome subunit X [Mus musculus]gi|2897809|dbj|BAA24917.1| PSMB5 [Mus musculus]gi|2897806|dbj|BAA24916.1| PSMB5 [Mus musculus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 8 days embryo whole body cDNA, RIKEN full-length enriched library, clone:5730444O07 product:proteasome [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_011186) proteasome (prosome, macropain) subunit, beta type 5; proteasome beta type subunit 5 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • proteasome (prosome, macropain) subunit, beta type 5 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Proteasome subunit beta type-5 precursor (Proteasome epsilon chain) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome subunit X) (Proteasome chain 6) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mCG8712, isoform CRA_b [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • PSMB5 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Proteasome (prosome, macropain) subunit, beta type 5 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • proteasome subunit X [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Psmb5 Proteasome subunit beta type-5 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Psmb5 Proteasome subunit beta type-5 precursor [ipi.MOUSE_jw_12may08.contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Psmb5 proteasome (prosome, macropain) subunit, beta type 5 [zeeyong.fasta]
  • Tax_Id=10090 Gene_Symbol=Psmb5 proteasome (prosome, macropain) subunit, beta type 5 ENSMUSG00000022193 IPI00317902 IPI00875197 IPI00473542 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • proteasome subunit beta type-5 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00317902.3|SWISS-PROT:O55234|ENSEMBL:ENSMUSP00000022803|REFSEQ:NP_035316 Tax_Id=10090 Gene_Symbol=Psmb5 Proteasome subunit beta type-5 [ipi.MOUSE.fasta.20090209]
  • Proteasome subunit beta type-5 OS=Mus musculus GN=Psmb5 [011711_HMR.fasta]
  • sp|O55234|PSB5_MOUSE Proteasome subunit beta type-5 OS=Mus musculus GN=Psmb5 PE=1 SV=3 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 264 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    cytoplasm [IEA]
    proteasome core complex [IDA]
    proteasome complex [IEA]
    Biological Process: response to oxidative stress [IDA]
    proteasomal ubiquitin-dependent protein catabolic process [IDA]
    proteolysis involved in cellular protein catabolic process [IEA]
    Molecular Function: endopeptidase activity [IEA]
    threonine-type endopeptidase activity [IEA]
    peptidase activity [IDA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALASVLQRP MPVNQHGFFG LGGGADLLDL GPGSPGDGLS LAAPSWGVPE EPRIEMLHGT  60
   61 TTLAFKFLHG VIVAADSRAT AGAYIASQTV KKVIEINPYL LGTMAGGAAD CSFWERLLAR 120
  121 QCRIYELRNK ERISVAAASK LLANMVYQYK GMGLSMGTMI CGWDKRGPGL YYVDSEGNRI 180
  181 SGTAFSVGSG SVYAYGVMDR GYSYDLKVEE AYDLARRAIY QATYRDAYSG GAVNLYHVRE 240
  241 DGWIRVSSDN VADLHDKYSS VSVP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264] PSI-BLAST 53.39794 Proteasome beta subunit (catalytic)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • endopeptidase activity
    		•  6.91642761177919 bayes_pls_golite062009
  • peptidase activity
    		•  6.84511694091156 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  6.5973571808298 bayes_pls_golite062009
  • hydrolase activity
    		•  4.47652590304822 bayes_pls_golite062009
  • threonine-type endopeptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • threonine-type peptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009
  • binding
    		•  0.982918122186083 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.448212653390607 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle