Protein Overview: sv-PC

General Information:
Name(s) found:	sv-PC / FBpp0088367 [FlyBase]
Description(s) found: Found 18 descriptions. SHOW ALL	The gene shaven is referred to in FlyBase by the symbol Dmel\sv (CG11049, FBgn0005561). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:1109444..1133943. It has the cytological map location 102F8. It is reported to have molecular function</span>: RNA polymerase II transcription factor activity; transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; neuron development; muscle organ development. 52 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: peripheral nervous system; external compound sense organ; nervous system; organ system; adult segment; compound cell cluster organ; rhabdomere; imaginal precursor; antennal segment; primary pigment cell; cell projection; unguis; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	647 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS]
Biological Process:	muscle organ development [IMP] neuron development [IMP] regulation of transcription [IEA][NAS] compound eye cone cell fate commitment [TAS] dendrite morphogenesis [IMP]
Molecular Function:	DNA binding [IEA] transcription factor activity [TAS] RNA polymerase II transcription factor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIMDIQTST HHIHGLGTHE LQHRILHPHI LHSTQEETLN TSTGQLEHDS QHLQQHHLTH  60
   61 HQQQDVSPTL HNLQNTRTGD SLSTTINTNQ NQHGHQHLSG SNMYTSSQME DKSKANKYDE 120
  121 YSSRTLSNIS DANTTPSANN FITQSQGIEW ITAMNDIQNG AEDSHSSQGS ISGDGHGGVN 180
  181 QLGGVFVNGR PLPDVVRQRI VELAHNGVRP CDISRQLRVS HGCVSKILSR YYETGSFKAG 240
  241 VIGGSKPKVA TPPVVDAIAN YKRENPTMFA WEIRDRLLAE AICSQDNVPS VSSINRIVRN 300
  301 KAAEKAKHVH HHQQHHVSQS LGGGHIATES VDSSTGTIGE PQPPTSNSSA NSVNTNVSAS 360
  361 ASVHASIPTS GTDSVQVSVG HINANSNETT HINSTAEQRT TGYSINGILG IQHGHHSHNN 420
  421 NNNSSVNNNN NTESSCKRKR IEAHDENHDT NIHSDNDDGK RQRMSTYSGD QLYTNIWSGK 480
  481 WCIKDDHKLL AELGNLTAST GNCPATYYEA SNGFSTTPIS GSGATASGND TSMLYDSITT 540
  541 ISQTQSSIYT PAIGPSIGCS SVVPGSDYAY NPAYTQYGGA YGSYGYGTGS GLINSSYYYE 600
  601 SGQTQSPLTH DLRSPLVATR ANSLASAASP GSGSACTKSE SSDIFLA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
transcription regulator activity	5.13863038737912	bayes_pls_golite062009
DNA binding	4.66369707598026	bayes_pls_golite062009
nucleic acid binding	4.51452285155271	bayes_pls_golite062009
transcription factor activity	4.06706589695599	bayes_pls_golite062009
sequence-specific DNA binding	3.5139760613123	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.16896789933192	bayes_pls_golite062009
transcription activator activity	3.10621734076555	bayes_pls_golite062009
binding	3.02779747447702	bayes_pls_golite062009
transcription repressor activity	1.91962622287073	bayes_pls_golite062009
protein binding	1.88087411289001	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.73068440195944	bayes_pls_golite062009
chromatin binding	1.68956710349366	bayes_pls_golite062009
transcription factor binding	1.40653841901929	bayes_pls_golite062009
transcription cofactor activity	0.84983974758882	bayes_pls_golite062009
transcription corepressor activity	0.25931464844298	bayes_pls_golite062009

Term	Confidence	Notes
transcription regulator activity	2.32498104079149	bayes_pls_golite062009
nucleic acid binding	2.0340444056235	bayes_pls_golite062009
DNA binding	1.96520460315172	bayes_pls_golite062009
pseudouridine synthase activity	1.95827425471645	bayes_pls_golite062009
catalytic activity	1.86133205308688	bayes_pls_golite062009
binding	1.39195733615426	bayes_pls_golite062009
transcription activator activity	1.27714242179739	bayes_pls_golite062009
protein binding	1.14602657647498	bayes_pls_golite062009
intramolecular transferase activity	0.667162168337187	bayes_pls_golite062009
isomerase activity	0.567803132409133	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..161]	deduced	N/A	No confident structure predictions are available.
2	View Details	[162..309]	PSI-BLAST	60.0	Pax-5
3	View Details	[310..427]	FFAS03	1.08	Crystal Structure of the Methanococcus jannaschii Cbf5 Nop10 Complex
4	View Details	[428..647]	MSA	8.325995	View MSA. No confident structure predictions are available.

Protein Overview: sv-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: