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Protein Overview: Trc8-PD

General Information:
Name(s) found: Trc8-PD / FBpp0089379 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene Trc8 is referred to in FlyBase by the symbol Dmel\Trc8 (CG2304, FBgn0039668). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25324562..25329519. It has the cytological map location 99B1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of growth; ventral midline development. 3 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 809 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDA]
    Biological Process: ventral midline development [IMP]
    negative regulation of growth [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRTKVLGL VDVMMRVPPV MVIDEILKMD MGMQSWLYPD KDKASGALAT PTEAPAVPSG  60
   61 QDPFTSIKEL FSHMTTSAQS VLEQSIEKAS EAAKTHGMLS SGFNSLMNEL SKDQTLADVL 120
  121 STTTVKFVLC VFAFLSAACI FMLWTRHLVM VYMFLTSLGL TFLSYWSNVS ALALTERSPS 180
  181 MVEDLMSLNT TRLLDSGGVV MSLAPHLMAQ WFMGMLFAYI HLGPRFEHVQ RSMPIIFASP 240
  241 ILLAMLPLPA KVVQHLPVVA VFTPIILTKI TLMQSAMEAS RTVYNGYQYA MNFVSNFGLS 300
  301 ALIENEWQRL NVPNVLRVFW TIRLIQGGYA LATTESDEPL DLMTATQKLL VDGCETMTAV 360
  361 LGMTGVISMF CHYIGRGFQW YLLTYDDEEK SLGTVSAVLF YILALQTGLT SLSPDKRFIR 420
  421 LCRNLCLLMT ALLHFLHNIV SPILMSLSAA RNPSRKRHVR ALSVCAFLVV LSVSLLYHLW 480
  481 SQQSISTWLL AVTAFSVEVV VKVLVSLATY TLFLLDARRQ FFWEKLDDYL YYVRAFGNSV 540
  541 EFCFGILLFI NGAWILIFES AQNATGGGIR AIMMCIHAYF NIWCEARAGW SVFMKRRSAV 600
  601 HKISALPEAT PAQLQAFDDV CAICYQEMYS AKITRCRHFF HGVCLRKWLY VQDRCPLCHE 660
  661 IMMYTDKADE NAPEAEPAPA AQAEQPMRIY PRDDANNAAA QRRSPERAPV EASEQAPATS 720
  721 SSSAAATIGA EAVSAIVESA AAVGEARSLV SVASSSSATH RISASGSSDS SYMTASAQSP 780
  781 PPTATSAAAV ATAAASNTTH MFRMSQDQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] deduced N/A No confident structure predictions are available.
    2 View Details [113..307] MSA 1.026975 View MSA. No confident structure predictions are available.
    3 View Details [308..516] MSA 2.203977 View MSA. No confident structure predictions are available.
    4 View Details [517..606] deduced N/A No confident structure predictions are available.
    5 View Details [607..727] PSI-BLAST 12.69897 RAG1 DIMERIZATION DOMAIN
    6 View Details [728..809] MSA 1.400995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  2.15929427993458 bayes_pls_golite062009
  • protein binding
    		•  1.49775478023418 bayes_pls_golite062009
  • chromatin binding
    		•  0.68064699307727 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.587037280321105 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.457219654632707 bayes_pls_golite062009
  • transcription factor binding
    		•  0.40077737329629 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.181063140818134 bayes_pls_golite062009
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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