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View Structure Prediction Details

Protein: Trc8-PD
Organism: Drosophila melanogaster
Length: 809 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Trc8-PD.

Description E-value Query
Range
Subject
Range
gi|18033962 - gi|18033962|gb|AAL57300.1|AF387786_1 TRC8 [Drosophila melanogaster]
706.0 [0..1] [809..1]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRTKVLGL VDVMMRVPPV MVIDEILKMD MGMQSWLYPD KDKASGALAT PTEAPAVPSG  60
   61 QDPFTSIKEL FSHMTTSAQS VLEQSIEKAS EAAKTHGMLS SGFNSLMNEL SK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [113-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQTLADVLST TTVKFVLCVF AFLSAACIFM LWTRHLVMVY MFLTSLGLTF LSYWSNVSAL  60
   61 ALTERSPSMV EDLMSLNTTR LLDSGGVVMS LAPHLMAQWF MGMLFAYIHL GPRFEHVQRS 120
  121 MPIIFASPIL LAMLPLPAKV VQHLPVVAVF TPIILTKITL MQSAMEASRT VYNGYQYAMN 180
  181 FVSNFGLSAL IENEW

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [308-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRLNVPNVLR VFWTIRLIQG GYALATTESD EPLDLMTATQ KLLVDGCETM TAVLGMTGVI  60
   61 SMFCHYIGRG FQWYLLTYDD EEKSLGTVSA VLFYILALQT GLTSLSPDKR FIRLCRNLCL 120
  121 LMTALLHFLH NIVSPILMSL SAARNPSRKR HVRALSVCAF LVVLSVSLLY HLWSQQSIST 180
  181 WLLAVTAFSV EVVVKVLVSL ATYTLFLLD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [517-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARRQFFWEKL DDYLYYVRAF GNSVEFCFGI LLFINGAWIL IFESAQNATG GGIRAIMMCI  60
   61 HAYFNIWCEA RAGWSVFMKR RSAVHKISAL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [607-727]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEATPAQLQA FDDVCAICYQ EMYSAKITRC RHFFHGVCLR KWLYVQDRCP LCHEIMMYTD  60
   61 KADENAPEAE PAPAAQAEQP MRIYPRDDAN NAAAQRRSPE RAPVEASEQA PATSSSSAAA 120
  121 T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 1rmdA
Description: RAG1 DIMERIZATION DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.15929427993458 bayes_pls_golite062009
protein binding 1.49775478023418 bayes_pls_golite062009
chromatin binding 0.68064699307727 bayes_pls_golite062009
small conjugating protein ligase activity 0.587037280321105 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.457219654632707 bayes_pls_golite062009
transcription factor binding 0.40077737329629 bayes_pls_golite062009
transcription regulator activity 0.181063140818134 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [728-809]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGAEAVSAIV ESAAAVGEAR SLVSVASSSS ATHRISASGS SDSSYMTASA QSPPPTATSA  60
   61 AAVATAAASN TTHMFRMSQD QQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle