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View Structure Prediction Details

Protein: Trc8-PD
Organism: Drosophila melanogaster
Length: 809 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Trc8-PD.

Description E-value Query
Range
Subject
Range
gi|18033962 - gi|18033962|gb|AAL57300.1|AF387786_1 TRC8 [Drosophila melanogaster]
706.0 [0..1] [809..1]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRTKVLGL VDVMMRVPPV MVIDEILKMD MGMQSWLYPD KDKASGALAT PTEAPAVPSG  60
   61 QDPFTSIKEL FSHMTTSAQS VLEQSIEKAS EAAKTHGMLS SGFNSLMNEL SK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [113-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQTLADVLST TTVKFVLCVF AFLSAACIFM LWTRHLVMVY MFLTSLGLTF LSYWSNVSAL  60
   61 ALTERSPSMV EDLMSLNTTR LLDSGGVVMS LAPHLMAQWF MGMLFAYIHL GPRFEHVQRS 120
  121 MPIIFASPIL LAMLPLPAKV VQHLPVVAVF TPIILTKITL MQSAMEASRT VYNGYQYAMN 180
  181 FVSNFGLSAL IENEW

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [308-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRLNVPNVLR VFWTIRLIQG GYALATTESD EPLDLMTATQ KLLVDGCETM TAVLGMTGVI  60
   61 SMFCHYIGRG FQWYLLTYDD EEKSLGTVSA VLFYILALQT GLTSLSPDKR FIRLCRNLCL 120
  121 LMTALLHFLH NIVSPILMSL SAARNPSRKR HVRALSVCAF LVVLSVSLLY HLWSQQSIST 180
  181 WLLAVTAFSV EVVVKVLVSL ATYTLFLLD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [517-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARRQFFWEKL DDYLYYVRAF GNSVEFCFGI LLFINGAWIL IFESAQNATG GGIRAIMMCI  60
   61 HAYFNIWCEA RAGWSVFMKR RSAVHKISAL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [607-727]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEATPAQLQA FDDVCAICYQ EMYSAKITRC RHFFHGVCLR KWLYVQDRCP LCHEIMMYTD  60
   61 KADENAPEAE PAPAAQAEQP MRIYPRDDAN NAAAQRRSPE RAPVEASEQA PATSSSSAAA 120
  121 T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 1rmdA
Description: RAG1 DIMERIZATION DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.15929427993458 bayes_pls_golite062009
protein binding 1.49775478023418 bayes_pls_golite062009
chromatin binding 0.68064699307727 bayes_pls_golite062009
small conjugating protein ligase activity 0.587037280321105 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.457219654632707 bayes_pls_golite062009
transcription factor binding 0.40077737329629 bayes_pls_golite062009
transcription regulator activity 0.181063140818134 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [728-809]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGAEAVSAIV ESAAAVGEAR SLVSVASSSS ATHRISASGS SDSSYMTASA QSPPPTATSA  60
   61 AAVATAAASN TTHMFRMSQD QQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle