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Protein Overview: gi|18204201, gi|...

General Information:
Name(s) found: gi|4191610 [NCBI NR]
gi|27552766 [NCBI NR]
gi|18204201 [NCBI NR]
Description(s) found:
Found 14 descriptions.
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  • gi|4191610|gb|AAD09827.1| IGF-II mRNA-binding protein 2 [Homo sapiens] [NCBI NR]
  • ref|NP_006539.2| IGF-II mRNA-binding protein 2 [Homo sapiens] [NCBI NR]
  • gi|18204201|gb|AAH21290.1| Insulin-like growth factor 2 mRNA binding protein 2 [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 598 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKLYIGNLS PAVTADDLRQ LFGDRKLPLA GQVLLKSGYA FVDYPDQNWA IRAIETLSGK  60
   61 VELHGKIMEV DYSVSKKLRS RKIQIRNIPP HLQWEVLDGL LAQYGTVENV EQVNTDTETA 120
  121 VVNVTYATRE EAKIAMEKLS GHQFENYSFK ISYIPDEEVS SPSPPQRAQR GDHSSREQGH 180
  181 APGGTSQARQ IDFPLRILVP TQFVGAIIGK EGLTIKNITK QTQSRVDIHR KENSGAAEKP 240
  241 VTIHATPEGT SEACRMILEI MQKEADETKL AEEIPLKILA HNGLVGRLIG KEGRNLKKIE 300
  301 HETGTKITIS SLQDLSIYNP ERTITVKGTV EACASAEIEI MKKLREAFEN DMLAVNQQAN 360
  361 LIPGLNLSAL GIFSTGLSVL SPPAGPRGAP PAAPYHPFTT HSGYFSSLYP HHQFGPFPHH 420
  421 HSYPEQEIVN LFIPTQAVGA IIGKKGAHIK QLARFAGASI KIAPAEGPDV SERMVIITGP 480
  481 PEAQFKAQGR IFGKLKEENF FNPKEEVKLE AHIRVPSSTA GRVIGKGGKT VNELQNLTSA 540
  541 EVIVPRDQTP DENEEVIVRI IGHFFASQTA QRKIREIVQQ VKQQEQKYPQ GVASQRSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] PSI-BLAST 10.522879 Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2
    2 View Details [80..272] FFAS03 4.16 Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
    3 View Details [273..598] PSI-BLAST 34.09691 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleic acid binding
    		•  4.51665560478175 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • mRNA binding
    		•  3.27529715028622 bayes_pls_golite062009
  • RNA binding
    		•  2.92438188845619 bayes_pls_golite062009
  • protein phosphatase 2B binding
    		•  1.92951040618845 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.7776932219095 bayes_pls_golite062009
  • DNA binding
    		•  1.65208390030564 bayes_pls_golite062009
  • structural molecule activity
    		•  1.56805212547627 bayes_pls_golite062009
  • mRNA 5'-UTR binding
    		•  1.30855696645617 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.998305828880243 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • transcription factor activity
    		•  0.795084003256395 bayes_pls_golite062009
  • translation repressor activity, nucleic acid binding
    		•  0.461000905454505 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.304235325881492 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.244426435307114 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.218661712638756 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.204324812791075 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.19367873260838 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.193140622784969 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009
    2
    Term Confidence Notes
  • nucleic acid binding
    		•  4.24798168496203 bayes_pls_golite062009
  • binding
    		•  3.48033873254013 bayes_pls_golite062009
  • mRNA binding
    		•  2.85410641023409 bayes_pls_golite062009
  • RNA binding
    		•  2.51560202858525 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.80010182784796 bayes_pls_golite062009
  • protein phosphatase 2B binding
    		•  1.77161287074147 bayes_pls_golite062009
  • DNA binding
    		•  1.65820497285332 bayes_pls_golite062009
  • structural molecule activity
    		•  1.57693236253086 bayes_pls_golite062009
  • protein binding
    		•  1.05805521997665 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.00459347347517 bayes_pls_golite062009
  • mRNA 5'-UTR binding
    		•  0.953943296217791 bayes_pls_golite062009
  • transcription factor activity
    		•  0.816233215115795 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.462558743683805 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.254075792503149 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.247717852494858 bayes_pls_golite062009
  • translation regulator activity
    		•  0.246220338604608 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.228597520924969 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.21401455640554 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.203379911534284 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.202841445688688 bayes_pls_golite062009
  • translation repressor activity, nucleic acid binding
    		•  0.147208072406136 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.0127733116412899 bayes_pls_golite062009
    3
    Term Confidence Notes
  • structural constituent of ribosome
    		•  3.39508649382543 bayes_pls_golite062009
  • structural molecule activity
    		•  3.17894283951424 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.90728659801871 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.75408506104351 bayes_pls_golite062009
  • DNA binding
    		•  1.50208874269692 bayes_pls_golite062009
  • binding
    		•  1.50032731466041 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.816735708111222 bayes_pls_golite062009
  • transcription termination factor activity
    		•  0.76362333646107 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.74386510772174 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.724034237880801 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.723781436250512 bayes_pls_golite062009
  • hydrolase activity
    		•  0.470557276000139 bayes_pls_golite062009
  • mRNA binding
    		•  0.396503273803591 bayes_pls_golite062009
  • protein binding
    		•  0.191135371876197 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.1757578095579 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle