| Protein: | gi|18204201, gi|... |
| Organism: | Homo sapiens |
| Length: | 598 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|18204201, gi|....
| Description | E-value | Query Range |
Subject Range |
|
|
4.0E-76 | [1..598] | [2..592] |
|
|
6.0E-75 | [1..598] | [2..599] |
|
|
8.0E-75 | [1..598] | [2..599] |
|
|
2.0E-73 | [1..598] | [211..801] |
|
|
9.0E-70 | [1..598] | [1..576] |
|
|
2.0E-69 | [1..598] | [1..554] |
|
Region A: Residues: [1-79] |
1 11 21 31 41 51
| | | | | |
1 MNKLYIGNLS PAVTADDLRQ LFGDRKLPLA GQVLLKSGYA FVDYPDQNWA IRAIETLSGK 60
61 VELHGKIMEV DYSVSKKLR
|
| Detection Method: |  |
| Confidence: | 10.522879 |
| Match: | 2cqhA |
| Description: | Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleic acid binding | 4.51665560478175 | bayes_pls_golite062009 |
| binding | 3.64400841800969 | bayes_pls_golite062009 |
| mRNA binding | 3.27529715028622 | bayes_pls_golite062009 |
| RNA binding | 2.92438188845619 | bayes_pls_golite062009 |
| protein phosphatase 2B binding | 1.92951040618845 | bayes_pls_golite062009 |
| transcription regulator activity | 1.7776932219095 | bayes_pls_golite062009 |
| DNA binding | 1.65208390030564 | bayes_pls_golite062009 |
| structural molecule activity | 1.56805212547627 | bayes_pls_golite062009 |
| mRNA 5'-UTR binding | 1.30855696645617 | bayes_pls_golite062009 |
| protein binding | 1.12215421354121 | bayes_pls_golite062009 |
| transcription repressor activity | 0.998305828880243 | bayes_pls_golite062009 |
| mRNA 3'-UTR binding | 0.824614388276642 | bayes_pls_golite062009 |
| transcription factor activity | 0.795084003256395 | bayes_pls_golite062009 |
| translation repressor activity, nucleic acid binding | 0.461000905454505 | bayes_pls_golite062009 |
| translation regulator activity | 0.38120065819101 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.304235325881492 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.244426435307114 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.218661712638756 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.204324812791075 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.19367873260838 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.193140622784969 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.128616879457381 | bayes_pls_golite062009 |
|
Region A: Residues: [80-272] |
1 11 21 31 41 51
| | | | | |
1 SRKIQIRNIP PHLQWEVLDG LLAQYGTVEN VEQVNTDTET AVVNVTYATR EEAKIAMEKL 60
61 SGHQFENYSF KISYIPDEEV SSPSPPQRAQ RGDHSSREQG HAPGGTSQAR QIDFPLRILV 120
121 PTQFVGAIIG KEGLTIKNIT KQTQSRVDIH RKENSGAAEK PVTIHATPEG TSEACRMILE 180
181 IMQKEADETK LAE
|
| Detection Method: | |
| Confidence: | 4.16 |
| Match: | 2adcA |
| Description: | Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleic acid binding | 4.24798168496203 | bayes_pls_golite062009 |
| binding | 3.48033873254013 | bayes_pls_golite062009 |
| mRNA binding | 2.85410641023409 | bayes_pls_golite062009 |
| RNA binding | 2.51560202858525 | bayes_pls_golite062009 |
| transcription regulator activity | 1.80010182784796 | bayes_pls_golite062009 |
| protein phosphatase 2B binding | 1.77161287074147 | bayes_pls_golite062009 |
| DNA binding | 1.65820497285332 | bayes_pls_golite062009 |
| structural molecule activity | 1.57693236253086 | bayes_pls_golite062009 |
| protein binding | 1.05805521997665 | bayes_pls_golite062009 |
| transcription repressor activity | 1.00459347347517 | bayes_pls_golite062009 |
| mRNA 5'-UTR binding | 0.953943296217791 | bayes_pls_golite062009 |
| transcription factor activity | 0.816233215115795 | bayes_pls_golite062009 |
| mRNA 3'-UTR binding | 0.462558743683805 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.254075792503149 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.247717852494858 | bayes_pls_golite062009 |
| translation regulator activity | 0.246220338604608 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.228597520924969 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.21401455640554 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.203379911534284 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.202841445688688 | bayes_pls_golite062009 |
| translation repressor activity, nucleic acid binding | 0.147208072406136 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.0127733116412899 | bayes_pls_golite062009 |
|
Region A: Residues: [273-598] |
1 11 21 31 41 51
| | | | | |
1 EIPLKILAHN GLVGRLIGKE GRNLKKIEHE TGTKITISSL QDLSIYNPER TITVKGTVEA 60
61 CASAEIEIMK KLREAFENDM LAVNQQANLI PGLNLSALGI FSTGLSVLSP PAGPRGAPPA 120
121 APYHPFTTHS GYFSSLYPHH QFGPFPHHHS YPEQEIVNLF IPTQAVGAII GKKGAHIKQL 180
181 ARFAGASIKI APAEGPDVSE RMVIITGPPE AQFKAQGRIF GKLKEENFFN PKEEVKLEAH 240
241 IRVPSSTAGR VIGKGGKTVN ELQNLTSAEV IVPRDQTPDE NEEVIVRIIG HFFASQTAQR 300
301 KIREIVQQVK QQEQKYPQGV ASQRSK
|
| Detection Method: | |
| Confidence: | 34.09691 |
| Match: | 1e3hA |
| Description: | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| structural constituent of ribosome | 3.39508649382543 | bayes_pls_golite062009 |
| structural molecule activity | 3.17894283951424 | bayes_pls_golite062009 |
| transcription regulator activity | 1.90728659801871 | bayes_pls_golite062009 |
| nucleic acid binding | 1.75408506104351 | bayes_pls_golite062009 |
| DNA binding | 1.50208874269692 | bayes_pls_golite062009 |
| binding | 1.50032731466041 | bayes_pls_golite062009 |
| catalytic activity | 0.878454819018611 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.816735708111222 | bayes_pls_golite062009 |
| transcription termination factor activity | 0.76362333646107 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.74386510772174 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.724034237880801 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.723781436250512 | bayes_pls_golite062009 |
| hydrolase activity | 0.470557276000139 | bayes_pls_golite062009 |
| mRNA binding | 0.396503273803591 | bayes_pls_golite062009 |
| protein binding | 0.191135371876197 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.1757578095579 | bayes_pls_golite062009 |
