Protein Overview: aub-PC

General Information:
Name(s) found:	aub-PC / FBpp0111705 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|161076864\|ref\|NP_001097144.1\| aubergine, isoform C [Drosophila melanogaster] [NCBI NR] gi\|157400143\|gb\|ABV53667.1\| aubergine, isoform C [Drosophila melanogaster] [NCBI NR] The gene aubergine is referred to in FlyBase by the symbol Dmel\aub (CG6137, FBgn0000146). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:10997819..11001489. It has the cytological map location 32C1. There is experimental evidence that it has the molecular function</span>: RNA binding. There is experimental evidence that it is involved in the biological process</span>: pole cell formation; regulation of pole plasm oskar mRNA localization; negative regulation of transposition; oogenesis; RNA interference; targeting of mRNA for destruction involved in RNA interference; pole plasm protein localization; oocyte maturation; chromatin silencing; dorsal appendage formation. 23 alleles are reported. The phenotypes of these alleles are annotated with: spermatid; karyosome; chorion; spermatocyte; dorsal appendage. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] type=protein; loc=2L:complement(10997932..10998832,10998897..10999007,10999061..10999450,10999518..10999672,10999727..10999854,10999914..11000106,11000165..11000658,11000786..11000801); ID=FBpp0111705; name=aub-PC; parent=FBgn0000146,FBtr0112793; dbxref=F [fly-100309-contam.fasta] type=protein; loc=2L:complement(10997932..10998832,10998897..10999007,10999061..10999450,10999518..10999672,10999727..10999854,10999914..11000106,11000165..11000658,11000786..11000801); ID=FBpp0111705; name=aub-PC; parent=FBgn0000146,FBtr0112793; dbxref=FlyBase:FBpp0111705,FlyBase_Annotation_IDs:CG6137-PC,REFSEQ:NP_001097144,GB_protein:ABV53667; MD5=fe8ba41ea7729ac8097bc36a5591bf00; length=795; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(10997932..10998832,10998897..10999007,10999061..10999450,10999518..10999672,10999727..10999854,10999914..11000106,11000165..11000658,11000786..11000801); ID=FBpp0111705; name=aub-PC; parent=FBgn0000146,FBtr0112793; dbxref=FlyBase:FBpp0111705,FlyBase_Annotation_IDs:CG6137-PC,REFSEQ:NP_001097144,GB_protein:ABV53667; MD5=fe8ba41ea7729ac8097bc36a5591bf00; length=795; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Aubergine, isoform C OS=Drosophila melanogaster GN=aub PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:complement(10997932..10998832,10998897..10999007,10999061..10999450,10999518..10999672,10999727..10999854,10999914..11000106,11000165..11000658,11000786..11000801); ID=FBpp0111705; name=aub-PC; parent=FBgn0000146,FBtr0112793; dbxref=FlyBase:FBpp0111705,FlyBase_Annotation_IDs:CG6137-PC,REFSEQ:NP_001097144,GB_protein:ABV53667,FlyMine:FBpp0111705,modMine:FBpp0111705; MD5=fe8ba41ea7729ac8097bc36a5591bf00; length=795; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(join(11000786..11000801,11000165..11000658,10999914..11000106,10999727..10999854,10999518..10999672,10999061..10999450,10998897..10999007,10997932..10998832)); ID=FBpp0111705; name=aub-PC; parent=FBgn0000146,FBtr0112793; dbxref=FlyBase:FBpp0111705,FlyBase_Annotation_IDs:CG6137-PC,REFSEQ:NP_001097144,GB_protein:ABV53667,FlyMine:FBpp0111705,modMine:FBpp0111705; MD5=fe8ba41ea7729ac8097bc36a5591bf00; length=795; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(11000786..11000801,11000165..11000658,10999914..11000106,10999727..10999854,10999518..10999672,10999061..10999450,10998897..10999007,10997932..10998832)); ID=FBpp0111705; name=aub-PC; parent=FBgn0000146,FBtr0112793; dbxref=FlyBase:FBpp0111705,FlyBase_Annotation_IDs:CG6137-PC,REFSEQ:NP_001097144,GB_protein:ABV53667,FlyMine:FBpp0111705,modMine:FBpp0111705; MD5=fe8ba41ea7729ac8097bc36a5591bf00; length=795; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of O76922, Isoform C of Protein aubergine OS=Drosophila melanogaster GN=aub [DROME.fasta.20160308] FBpp0111705 type=protein; loc=2L:complement(join(11000786..11000801,11000165..11000658,10999914..11000106,10999727..10999854,10999518..10999672,10999061..10999450,10998897..10999007,10997932..10998832)); ID=FBpp0111705; name=aub-PC; parent=FBgn0000146,FBtr0112793; dbxref=FlyBase:FBpp0111705,FlyBase_Annotation_IDs:CG6137-PC,REFSEQ:NP_001097144,GB_protein:ABV53667,FlyMine:FBpp0111705,modMine:FBpp0111705; MD5=fe8ba41ea7729ac8097bc36a5591bf00; length=795; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(11000786..11000801,11000165..11000658,10999914..11000106,10999727..10999854,10999518..10999672,10999061..10999450,10998897..10999007,10997932..10998832)); ID=FBpp0111705; name=aub-PC; parent=FBgn0000146,FBtr0112793; dbxref=FlyBase:FBpp0111705,FlyBase_Annotation_IDs:CG6137-PC,REFSEQ:NP_001097144,GB_protein:ABV53667,FlyMine:FBpp0111705,modMine:FBpp0111705; MD5=fe8ba41ea7729ac8097bc36a5591bf00; length=795; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	795 amino acids
Gene Ontology:
Cellular Component:	catalytic step 2 spliceosome [IDA] cytoplasm [IDA] precatalytic spliceosome [IDA] P granule [IDA]
Biological Process:	cystoblast division [ISS] dorsal appendage formation [IMP] pole cell formation [IGI] chromatin silencing [IMP] regulation of translational initiation [ISS] nuclear mRNA splicing, via spliceosome [IC] regulation of pole plasm oskar mRNA localization [IMP] oocyte maturation [IMP] pole plasm protein localization [IMP] oogenesis [IMP][TAS] regulation of oskar mRNA translation [TAS] maintenance of pole plasm mRNA location [TAS] negative regulation of transposition [IMP] positive regulation of oskar mRNA translation [NAS][TAS] karyosome formation [TAS] stem cell division [ISS] RNA interference [IMP][TAS] targeting of mRNA for destruction involved in RNA interference [IMP]
Molecular Function:	RNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKSEGDPRG SVRGRRLITD LVYSRPPGMT SKKGVVGTHI TVQANYFKVL KRPNWTIYQY  60
   61 RVDFTPDVEA TRLRRSFLYE HKGILGGYIF DGTNMFCINQ FKAVQDSPYV LELVTKSRAG 120
  121 ENIEIKIKAV GSVQSTDAEQ FQVLNLILRR AMEGLDLKLV SRYYYDPQAK INLENFRMQL 180
  181 WPGYQTSIRQ HENDILLCSE ICHKVMRTET LYNILSDAIR DSDDYQSTFK RAVMGMVILT 240
  241 DYNNKTYRID DVDFQSTPLC KFKTNDGEIS YVDYYKKRYN IIIRDLKQPL VMSRPTDKNI 300
  301 RGGNDQAIMI IPELARATGM TDAMRADFRT LRAMSEHTRL NPDRRIERLR MFNKRLKSCK 360
  361 QSVETLKSWN IELDSALVEI PARVLPPEKI LFGNQKIFVC DARADWTNEF RTCSMFKNVH 420
  421 INRWYVITPS RNLRETQEFV QMCIRTASSM KMNICNPIYE EIPDDRNGTY SQAIDNAAAN 480
  481 DPQIVMVVMR SPNEEKYSCI KKRTCVDRPV PSQVVTLKVI APRQQKPTGL MSIATKVVIQ 540
  541 MNAKLMGAPW QVVIPLHGLM TVGFDVCHSP KNKNKSYGAF VATMDQKESF RYFSTVNEHI 600
  601 KGQELSEQMS VNMACALRSY QEQHRSLPER ILFFRDGVGD GQLYQVVNSE VNTLKDRLDE 660
  661 IYKSAGKQEG CRMTFIIVSK RINSRYFTGH RNPVPGTVVD DVITLPERYD FFLVSQAVRI 720
  721 GTVSPTSYNV ISDNMGLNAD KLQMLSYKMT HMYYNYSGTI RVPAVCHYAH KLAFLVAESI 780
  781 NRAPSAGLQN QLYFL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: aub-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: