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Protein Overview: FBpp0292445

General Information:
Name(s) found: FBpp0292445 [FlyBase]
Description(s) found:
Found 16 descriptions.
SHOW ALL
  • type=protein; loc=2L:join(5109146..5111021,5117577..5117638,5121676..5121948,5122435..5122601,5122661..5122937,5123016..5125622,5125828..5139015,5139359..5139673,5139779..5140921,5141311..5141517,5141653..5141890,5142003..5144785,5146993..5147298,5148731..5148882,5154248..5155217,5155322..5155534,5155589..5155849,5157874..5157984); ID=FBpp0292445; name=Msp300-PB; parent=FBgn0261836,FBtr0303383; dbxref=FlyBase_Annotation_IDs:CG42768-PB,FlyBase:FBpp0292445,FlyBase:FBpp0078660,FlyBase_Annotation_IDs:CG33715-PB,REFSEQ:NP_001188692,GB_protein:ADV36942,FlyMine:FBpp0292445,modMine:FBpp0292445; MD5=b6233e47bee5def77f6472caffd24c8f; length=8382; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 8382 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDA]
    Z disc [IDA]
    cytoplasm [IDA]
    actin cytoskeleton [IDA]
    integrin complex [IDA]
    Biological Process: cytoskeleton organization [ISS]
    establishment of nucleus localization [IMP]
    skeletal muscle tissue development [IMP]
    mesoderm development [NAS]
    female germline ring canal stabilization [IMP]
    transcription from RNA polymerase II promoter [NAS]
    actin filament organization [IMP]
    cell migration [IMP]
    regulation of Rab GTPase activity [IEA]
    cytoplasmic transport, nurse cell to oocyte [IMP]
    Molecular Function: actin binding [IDA][ISS][NAS]
    RNA polymerase II transcription factor activity [NAS]
    double-stranded RNA binding [NAS]
    Rab GTPase activator activity [IEA]
    cytoskeletal protein binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADSGGPGSK HMDPTTIDAG GGGAGAAGGD DVPPVPAVRR RRAHEQKSSR EQVLEEEKSQ  60
   61 QLETSTVTRT YMKTITTSLT TSSSSNVEEF ILGEHAAGAA AAPSPNQQRL RQKVAQYEKV 120
  121 WSDGSSPVKR PAEQSSDELR LTDDQDEYDA ENPFEIDVHE IERRLRQERQ RGLAEAEAAK 180
  181 LAFQQVQLRH TTPPRRVEVT SDQVASPFNV TLRTTSRMSP GAEHGNVEEH LAPFNVTLRT 240
  241 TRRTKKKEFK ELENFLEGER TVREVPSADG VRTIITSSMT SDGGYAEEKI YRHGEGYVSP 300
  301 RDSPSWSRSS YSSERSSVTP PRSVDLTAGG RRILIKLEQE SELTEENQTR DETDLSFGRQ 360
  361 EVAMATGNID ITVGGSNPRR RLYQQTTVQV GGGNRTSPQD STPQRPRDLD LAGTTKTMLT 420
  421 STPIGTKEQP QTGPKTLVSP AATCQLRGSS TEEPRKIVSH KTITSTTTKS TSSSTSATSS 480
  481 SSTSRKLIET SPVVVGKIAQ IRTGKSNASD NDIDIDNDSD TEGRPASSIV IVSTPTRPTT 540
  541 PATASVSASA VTPSASISAT AAHALSGIGT FSKSLRQDYQ TLATQSGRSN ESPSDQEYQE 600
  601 FQSTMASINY ARSNSQYDSH IKEKREEQER VQKKTFTNWI NSYLLKRVPP LRIDDLINDL 660
  661 RDGTKLIALL EVLSGERLPV EKGRVLRRPH FLSNANTALQ FLASKRIKLV NINPADLVDG 720
  721 RPPVVLGLIW TIILYFQIEE NSRNLEYLGH GIGGSVSSLD SVGNQKHGDL KAEKWKQGAR 780
  781 KTLLNWVTNA LPKDSGVEVK DFGASWRDGV AFLALIDAIK ANLVNLAELK KTSNRQRLET 840
  841 AFDVAESKLG IAKLLDAEDV DVPKPDEKSI MTYVAQFLHK YPEPKGASRD QSHVQQEADE 900
  901 LRRFLVEKTT EYEPMVMMSS FPRDFGEYLL ARSEVDAHLA AYNRLKQLIE SQSGFLQVSR 960
  961 QSWEEINELW QRLQYQMMYW LWLLDSELPG DFGTVGKWLA EAEKLLMDND IPNAMNEETA1020
 1021 AVISRKLEEH KLFFADLPRI LAMFDNAKRS PVAQQIPLEQ LRNMERRLQE VGPKAAERRI1080
 1081 RLKFLEHKCC LIAFLNLVEN KMRGWTGKYG HEEKVAQQLE QYKNFVSRNK IFQEFQKAFV1140
 1141 DMQQVVEEYK RDGNVPRKEI NDIDRFMYET EERWKRVSME LKCCQNSLEE VVNCWRSWNQ1200
 1201 LAPTCEEWLQ LAEQKVNQSE DERLDFFQDI PVWKDKFDAL ASSANYLIAS CEEPIAQQLR1260
 1261 QRHGALSERF ERLFANTKQY MHAGDIIRSR QEYKSGIEQL SRWLRGAESV LDQRQVLGNS1320
 1321 EQVKEYGQQL QQLASEIDDN EELFKTISRN FQSLIQDLSR DEVDKMMKLL KQEKESLVRI1380
 1381 RAQLPAKLHL FHQLQIQQES LEAGQKEIHQ WLSEAEQLLG THNLSGGRDA INEQLHKHKT1440
 1441 YFSRTVYYRS MLESKNKVFQ NLLKAVSSDD KIDTAPASQQ MQQLNERFNY VIQNAQQWEQ1500
 1501 RLDSAAGGWS NFKDNERVVS EWLTQAESML VEKHIESKTT IETQKYFFEQ VNDRWMNDLV1560
 1561 QSAQQLLTTL PAQEQPAVVH SVEQLQSRWK NVLSQAPLHL LKLEFRLDEN AFYQSLKDVE1620
 1621 KELQLEQQAL NRNEDVDSIL QRNQQFLLQQ DVVPRLERCL QNMQRLAQAH RQQQPGDISL1680
 1681 DQAYDNAKSQ WQLLSNKLGD MRQTLQQIPA QWQGYHLKFN DMVDWMNGVD QSLKNIVNEV1740
 1741 NTMEEFEKEK VVFQKICQDA DNKREDMKWL VKTLDSLLSY ATEDEANLEQ KKLEDLIARY1800
 1801 KNLIPTIEIT MVKTEVFSKC YTYRREVHEV VCLLSKVKDQ TANIPAPDSL DRVNRLIEEQ1860
 1861 QYAINQLDHQ RPHIMSMLQR GRDLIKDVHA PAFVNAEVKN LETGWNQAYT ETSDKLQALK1920
 1921 GTQAVWSEFV DQKNDIFSML QTAETELRSL TPLQTDPKNV SQDLKSKRDL NVQLQQASHQ1980
 1981 LLPKLHALKS ELAPLAAPDK RPILEKEVTE VEKMFFNTME HVKDRVGYLE DYSAKWNNYK2040
 2041 TRLAELQEWA NKVAPKNIEA LQSEDLTPEE RVVKVQAFKR ILGDRMKQLD LLAADASELA2100
 2101 PKEGNIAEAK RLKGEITKLQ EVLSAINRNV DHQAQAVQED LVNWQQFQAG LQQIKPAVEQ2160
 2161 SEVKVNNVVS KPISLEEAVA MQQNAQQFET QCQEQLDKLH GISNISHKML CKTNAPDELD2220
 2221 AMHSRWTAVH ENAKQASAKL EKLVANWKSF DADAAKLEDW VGQGEQQMSR RPAVLNTPHI2280
 2281 DKLEKELVKL KSFNNEISQQ QAKLVTLGQN ADQISLHLAP EGAAALKDRV NQMKGKLQKL2340
 2341 SEATRGHINE VSDAIISRQD FNAKLVNFSN WMEQLRNQVT QVEEINPERV ETSLHVIHAL2400
 2401 LQEHADKKPS FNAIYDEVKQ LALGATPEES NALNDAYTAL VVNYQNLETN MLQKKAALEK2460
 2461 WTELLGWKND TESHLNYLKH QLDKPEGPAA EELSKVIDEI DNLGQGIGYW KGQAKEIDEN2520
 2521 PAIQLRDALS RRPLIATQIV NDVENKLENL KLRSQSQQQQ IQQMTVRKDK FHALEHNFGQ2580
 2581 ALQENRAKLD EILRQHPTLN NIDQIIADLV ALNDALKYQA DLKNRIHDEG SLLMREDIAS2640
 2641 MPAIQESLLI MDKNYDSLQN EIADRIQKYN LISQALREYA DSKDKFSKEL KKAEDLYNAI2700
 2701 PQQPRDETEL HQASEKTRKT MEQLRKSKLS LDELERRGNN VGKLFSAIGE PIPQEVPQEV2760
 2761 TAAKQHWQDL HDKTAKNAHV YETEAVIWSQ IEDAKKDLLP WLSETNQGLC DAADNSIEIE2820
 2821 FGPMRLSKYR TELPSYQALK DSIVEKTNDL VKINKGAEIP ALSALNKLLS EQFAEVNNNA2880
 2881 DRLSAITTSF NDQEQELRRR SKEAGERVSK LREQLIKCDD MSGDNNKIME RLQQCRALRG2940
 2941 ELDNSGNEID NIKQKVDELR NLYPTFSESI IPKELNNVQK RYENVDLYAK KIESSLLQFL3000
 3001 KKFHADKVGM LKRIIATQRE KVAWCQPESS SDKYNLDVKK SSLQEVSKSI DDCKARHAET3060
 3061 LKSLEMLKAV ESPQNLAELT SDAELLRKDM QALQDSFDQI KGILDENVDL WSQYEQSNEQ3120
 3121 ISNWLRDVEG RVKAETSSQV NLSEVPQKLQ ELSILQQDVL AHEPIINNLE QTSQQLIEKN3180
 3181 PEARIGQFVT HLVQRYQAVS KALTSYIDKI RGAQLSNANF AKAAKDFNEW FGDAKIEFQE3240
 3241 LARMGSPGSS SATAQQLQTV KNYIKTFDNG QILLNNAVDI GEALYPVVSP DNRERIRADL3300
 3301 RQMREKFDYL RDEANAFMQQ VEGVLIQKTS IEESYTQVSH YLNESKAKVP TTDELYPTLA3360
 3361 TKKAALQNYK TQLQEITLHK NALKQLHDKA VTLCDDESER KTDESIQEYN TLSKKISDRI3420
 3421 TTVGNHVVKH EAYDQVLEKA QDWLNTIKSE AIDILNETTF EKEGAEEKLL VVENLLQHKP3480
 3481 EGDSIFDTCH KLLETVLTQT HPSGHPALLK GFEEPKQSWE DFMTLCQDSL VKLKQLCSKW3540
 3541 DEFDTIIEEL DNWMKNVEAV VKNQNLKSTA EAKNAHLKQL QDISKDIERR GAAINELMDQ3600
 3601 GREIEGETDL NLKLSRLNTR YQTLKNLCKE SIAKYVNYVK DHESFDKDFD SFKQNLQSSV3660
 3661 DELAKTNEIV GDQSVLQDQQ NKLREMSDKR ILDSTLFEGL IDRGEKLYGH TSPEGREIIR3720
 3721 QQLRALRTLW DNYTDDLNSA TQKIDQCLLQ FNEFSIAQDQ LTKWLKDVDK AMQSHTEPKT3780
 3781 TLQEKRAQLQ NHKLLHQEIT THNVLVDNVC DKAQILVDQI KDNSLNVYLT SIKQLFQSIV3840
 3841 QKSDEILHNL DDCVQKHNEL NNALSSAKTW ISNEKAKLLE CDDAYGEKAD IKRKIETLGQ3900
 3901 LAQNKPQAMK IISDIRDLFE KVKATTSEKG NEVLDKEIEE LETTMKSHFD DIEGIEGKQK3960
 3961 DVLAQWDKFE KALEELTKWC RSAEAVFREQ QLQSTLHEKV EQLEKYKIQR ELILQKEKEI4020
 4021 DAFGDAAHAL LNNCGADRLK TLTTQITNRY QLLQVLSKEV VNRWSNLVDD HQFYQDKYNE4080
 4081 VDLWLQPIES QMAKVLLDEP TQSSNILQVL LSEKEQAESL FAALNAAGEK ALPETSTQGR4140
 4141 EKIRKDLRDI RDRWDKLDEG IRNLEKRQEA QGVQLSSYQD ILNQTVNWLD QVEKLIHNEN4200
 4201 PASWTSAQEI RSKLYKYKAT NQDINSHKRI VEAVNEKAAA LLGSAAPANA DEISKAVAEV4260
 4261 NKRYDQVGQD CAKLVADLDG AFDVYQQFSE LQKAQQDYQK NLWDRLTGYS DYSGNKAALQ4320
 4321 ARLQKINEIQ DALPEGVAKL KSLEDHIEQQ ASNIPARSKE VMARDLANLH ADFEKFGASL4380
 4381 SDVKSGLENR LQQWNDYEIN LDRLITWLGE AENSLKNYNL KSSFEEKEEQ LNGFQSLAQN4440
 4441 LRQNEADFDK VKDDTSELVQ SSGETRIAVN VQQVSSRFQS IQATAKEILK KCEQAVQDHG4500
 4501 HFNDKYKQCA DWLANAQARY DDCCDLSTVA SRDDLLKKQV VIQELLAQQP TATQLLNSTV4560
 4561 ELGEKCYGST ATEGREAIRS QLDDLTFDQL FDNIAITARK IQDKIAKWSG FDEIADSLKS4620
 4621 WLDETENALP ADIELKTTLD EKRNKLQTYR DILNDINNHQ VELGNLQEIA ANLPEKTELV4680
 4681 DQIIKDISDR FGKLQKRAQN YVERYEGIVS AHQQYSKAVM DAQEFIDATL NTVHYWGDLD4740
 4741 LEQISLHTNL DRLKNLKASL ADEFPRVDQV RALGEKVIPG TVDVGQVNIK SQIDTTQQEW4800
 4801 ESLLTTISST IEAIEARLQH WSEYEQLRDQ CLAWIRDTDN NLHAIDLKED LPKKRAQLDA4860
 4861 LKALQGDVRA KELEVDNVTE KAQTLLKGPS SNRASGPELV TKYQQIFHKV KELNNRWQQY4920
 4921 VTSHEDFDNA ISDCSSWINE IKEKLDYCSD MSSMSPKELD KKLATIQDVI LLKDEGSARV4980
 4981 LKILEQAQHV LANTAPGGHE AINKELTDLQ DLWSGIALRI MDVKSNLDDS ITQWSGFLDQ5040
 5041 VQNVRKFNEW LDGQVKELSE HQTTMTEKRA QLDRVKSTEE KVRVEKIDVD ALKIQAKEMI5100
 5101 ASGQQSQAAF QAQKVLDTFD ELFAKTQKLL SHRQDQYRDH RLFKEAYDDL VSWIGRAREK5160
 5161 FPSLKQSSLS DKLAIENAVQ ATEALLNKQA QGELLVEHLV HTGEVVLAST SAQGQEIIRN5220
 5221 DIRALRDSFE GLFREINQQK ENLEVTMVQW RAYKEEYERL MEWLQQIDIL VKNHKLNLCP5280
 5281 NLPEKEKQVA DMKEVMSRLE KGKDDIDKFN ASAASLLKSH LDTYVNNQLR HLSSVYQVQV5340
 5341 NLAKDVLKKV ETNRDQHREY DANMKSAKDW IANAKATIQS AGEGAGSKEA LQRRLEQIQD5400
 5401 LIRNRELGQN LVHTAINNGE KIIRNTRSDG RDAINTEMKE LQTEWDRLVK KMSTAKVQLE5460
 5461 TNLLQWADYS SSYSQLQQWI TDREAKLQQA CEQKIVKSKR GQPGLSSGLS ERKANLRQTN5520
 5521 NIVQDIVSFE PMIQSVTSKA SVLQQGAPGT EISDKYENLT KQAKDLYEKQ KNTIESYQSL5580
 5581 IDAGNEFATW LRNAKERLSK CSEPTGDKQA LAEKTHQLKI LQGELPEGAQ KLKNALEQGE5640
 5641 IACRSAEPED CEIIEQEVAL LQEEFDAYRE ALNKAKDYLE VGIVKWSDYQ DQYTEALEWL5700
 5701 SKTEALVQSY NKLQDSLIQK KVVLEQFQGH LQTLFDWQKT LDDLNMKAQV LLETCSDTRI5760
 5761 SNAIMQLTTK YNALLTLAKE VMRRLEMHYQ EHQQHHSLYE ECQSWIEKTR EKLSECEQIP5820
 5821 GTLNEVQIKL NTVKNLRQGF ETGQNKLRYL LELKEKVIMN TEQNGAAKIQ EDTEALKQDF5880
 5881 DKLLVDLNDV RQKLANRLAQ LEEIFKLYKI LIEWLEDVEP SVKTSDEFLN DLSEKRAALE5940
 5941 KFRVIQRDIN GHNDIVEKIN QRLKEDNSLD LKDFQPGLTK FDDLQTQVNK IIESLENQVN6000
 6001 SHEKYKQAYN ELQDWLRRTR IEVEQCADCH GEKDQVESRL NRLGDIQSSS LEGKALLEAC6060
 6061 EELSQAVIAT SGSEGQDNVA QEIKHLTSEW ETLQTISRDA RSSLESCLAA WQTFLQKFNK6120
 6121 INLWIETMNK RVTKSQEGEN KTPEDLVNAK KLLEEVLAEK DNVEDLNDNC ELLMEQSACT6180
 6181 RIRDQTIETQ ANYTKLLTSA QGLVAKIEKN LSDHTEFLNY KKEMDAWIEK AQQVLDDCST6240
 6241 DGDAAIIAQK LDTVNSLASR LPEGQHLLAL VQDAYSKASN ITPEDKQEKL RELMTKVRED6300
 6301 WDALGLAVKQ KLSDLKQAQN RWNDFAANKD KLEKWLNETE TTLKVAPETK GELSEMKTLL6360
 6361 ERYKTLSNEL KLKGNELEQL QSEARDLGTE VDAVNRLQSR CDKLKNDCSA HITALEQEMF6420
 6421 DYNAYHQSLQ DVEKWLLQIS FQLMAHNSLF ISNREQTQEQ IKQHEALLVE IQKYQTNLDD6480
 6481 LNAKGQAQIK RYESSTPAIR PTVESQLKNI QDSYNSLLQT SVQIKNRLLE SLAKFQEYED6540
 6541 TLDSIMRNLE TYEPIIQTEL DAPATSLELA QNQLRCAQEM QNKLNNEKSR LAAAVQACEA6600
 6601 ATASISRPSS PLETAMQAIP ERELIVRAKL EDLLDQKPPP KTRSSTGGVS TDDDKDEADV6660
 6661 EIQVELSDVN EALLDPIAHE RVKNYRRIVR LNSAHVGKLN ELVAKVQSHL GGLTASVSEL6720
 6721 EQQQKQRAEL QDWVKKQQSS VSDWMMRPCK LRPEAAQQEL VSMNDLLNSI GDKRSQLMLE6780
 6781 MTGSLGDEDT DLDDNIDKLE SELMDAIAKK QAGQNVIDGY RQGMADVQNW FDTLIKRMDV6840
 6841 LDRGSGLNCA QKMAAINEIK NEYELQGHPK IQELKGKAAQ VAEVISNLDG QQVEEQMKSL6900
 6901 DRRFADLGKR IDRKSQLLDV TNKGVEGAKG EIDQLQNWVK QQIEELQAPK PLGYTPKDAE6960
 6961 ARQQKIKSLM KDAEAKQSLA DVLEKRVANM QQELEPVEYS QLESALRNLN TENRNLSGVL7020
 7021 KAELDRALEA SKARKSLEND LDKARQWLKT KISEVRKLPV YHPLTSAEIE KKIQENRKYD7080
 7081 DDAKQFNDSV LTDVQRQAAN IMKDCDDADK AALQQILDEI AADYQTLKDE SSKRGKSLDD7140
 7141 LLQGRKAFED SMKNMGDWLN EMETATEGEL RTTSLPVLEE QLAHYKKLLS DAENKGGLIN7200
 7201 DVSEQGKSIL PTLSNADKLK LNDDIKNMKD RYGRIKNTID DRVNALGDHI KKYKDAKSRL7260
 7261 AECSQFLGNI QQKLRELNRP IGSRIEDVQD LLGAYEGILK ELKDSKSKMG DMQMDDLPEL7320
 7321 QSILAQQDDM IKLIEDQLAH LRQLLLLREQ FIALINEIIA FIMKYTDVII DIENSPDSLE7380
 7381 DKINKYDDVI VKIQECEGVL ASANDKGQKI ASEGNAADKN SITEQLQSLK NQLQNLRKAV7440
 7441 ESQRQKHQLQ LESHKKMAAE LSEILDWLHS HEGAAKSRPL LDRDPESVER ELQKHQSLSQ7500
 7501 DIESYLNKFN KINDGVKTEI GMPSSLLEML SEGRSLVASL PHELEEREKY LKNNRDSRLE7560
 7561 YMQLVAKFND WVHEAELRLQ NSQHGIDYEH LVQDLDEHKI FFGNEAPIRN LVHKQIQEAA7620
 7621 DKIWSSLNNY EQSELSAELA QFQTKLTNTL ANAKTQQSEL EKEAERWREY QQSIDRVKAT7680
 7681 IERTKFVDEP VQNLAGLHFN IQKLSHAIGN VQSQNSDLTL VNQQAQSLIR QADARNRQLI7740
 7741 EQDNAGLNRS WQDLVRSLEQ RRDNLQQLAE HWDGFENSLH AWEKALGRLE DKFRNVDPTV7800
 7801 RSRRHLEDTK NAIQELREES NQLKSSHKEI EALSKSILTF LGEVHKPSAE AIQAKVDKLV7860
 7861 EQQAKLNDTL RDKEQQVSKD LEEIEQVFRR ISQLQDKLNA LHEQLQSVHV YDEHIAQTEQ7920
 7921 LLITLNSQVQ QAAEESKLLV AQTTAHYQAK QNQLPSDIAQ EFTALELLAE RVQVTMETKE7980
 7981 KDFKRAKTVR TEYVDGVDEV QRWLLQAEVQ VQERSLTPTQ MKELLQRINH EITAIYERFT8040
 8041 LVKTNGQLII ENCRNSEEKT LVQTTIDQLA ASLAQVRGWL DEKKQAVGDS LDAWTRFMNL8100
 8101 YQIVMSWASE KRNFIDQTIE LRTLPEARNK LNDYVTSVKS IKPIVKHLSE MDKELEHIGQ8160
 8161 VTTVGDLKDK LQEAEDAKIS VEAVLLERNS LLQEACEEWD QCERKIKDIR SWHEKTKQGL8220
 8221 DSSQQQKKPL RDQLGFCEKT LADINVQKTK LRLSIEKLEV HFRNGMGGDP RLSENVDDLV8280
 8281 RVLDGLGELV KAKSQSLEQT LAQIDVYQQQ MQSLRQRIIQ EEQQLRLVMA PTYLPHDRER8340
 8341 ALAEQQACRE RVKNLHSKIT ARNERIKLLI HRGTPDDAKL EI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle