General Information: |
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Name(s) found: |
PDGFB_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 225 amino acids |
Gene Ontology: |
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Cellular Component: |
platelet alpha granule lumen
[UNKNOWN]
cytoplasm [IDA] membrane [IEA] extracellular region [UNKNOWN][IEA] cell surface [UNKNOWN][IEA] |
Biological Process: |
positive regulation of MAP kinase activity
[UNKNOWN][IEA]
response to estrogen stimulus [IEP] DNA replication [IEP] cell projection assembly [UNKNOWN][IEA] positive regulation of cell proliferation [UNKNOWN] transforming growth factor beta receptor signaling pathway [IMP] response to wounding [UNKNOWN] positive regulation of fibroblast growth factor receptor signaling pathway [UNKNOWN][IEA] positive regulation of DNA replication [UNKNOWN][IEA] epithelial cell proliferation involved in salivary gland morphogenesis [UNKNOWN][IEA] branching involved in salivary gland morphogenesis [UNKNOWN][IEA] cell chemotaxis [UNKNOWN][IEA] positive regulation of smooth muscle cell proliferation [IMP] regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA] wound healing [IEP] response to hypoxia [IEP] response to insulin stimulus [IEP] positive regulation of cell division [IEA] positive regulation of fibroblast proliferation [UNKNOWN][IEA] negative regulation of phosphatidylinositol biosynthetic process [UNKNOWN][IEA] positive regulation of smooth muscle cell migration [UNKNOWN][IMP] response to organic substance [IEP] platelet-derived growth factor receptor signaling pathway [UNKNOWN][IMP] response to organic cyclic substance [IEP] regulation of cell proliferation [IEP] positive regulation of blood vessel endothelial cell migration [UNKNOWN][IEA] monocyte chemotaxis [UNKNOWN][IEA] response to drug [IEP] response to estradiol stimulus [IEP] negative regulation of platelet activation [UNKNOWN][IEA] substrate-bound cell migration [UNKNOWN][IEA] positive regulation of endothelial cell proliferation [UNKNOWN][IEA] actin cytoskeleton organization [UNKNOWN][IEA] positive regulation of chemotaxis [UNKNOWN][IEA] cellular response to mycophenolic acid [IDA] cell growth [IEP] negative regulation of cell migration [UNKNOWN][IEA] |
Molecular Function: |
growth factor activity
[IEA]
protein binding [UNKNOWN] protein homodimerization activity [UNKNOWN][IEA] platelet-derived growth factor receptor binding [UNKNOWN][IMP] collagen binding [UNKNOWN][IEA] protein heterodimerization activity [UNKNOWN][IEA] cell surface binding [UNKNOWN][IEA] platelet-derived growth factor binding [UNKNOWN][IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 LPLCCYLRLV SAEGDPIPEE LYEMLSDHSI RSFDDLQRLL HRDSVDEDGA ELDLNMTRAH 60 61 SGVESESSSR GRRSLGSLAA AEPAVIAECK TRTEVFQISR NLIDRTNANF LVWPPCVEVQ 120 121 RCSGCCNNRN VQCRASQVQM RPVQVRKIEI VRKKPVFKKA TVTLEDHLAC KCETVVTPRP 180 181 VTRSPGTSRE HRAKTPQTRV TVRTVRIRRP PKGKHRKFKH THDKK |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)